1T1F
Crystal Structure of Native Antithrombin in its Monomeric Form
Summary for 1T1F
Entry DOI | 10.2210/pdb1t1f/pdb |
Descriptor | Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | serine-cysteine proteinase inhibitor; thrombin; human; x-ray crystallography, blood clotting |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space: P01008 |
Total number of polymer chains | 3 |
Total formula weight | 154520.50 |
Authors | Johnson, D.J.D.,Huntington, J.A. (deposition date: 2004-04-16, release date: 2005-10-04, Last modification date: 2023-08-23) |
Primary citation | Johnson, D.J.D.,Langdown, J.,Li, W.,Luis, S.A.,Baglin, T.P.,Huntington, J.A. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation J.Biol.Chem., 281:35478-35486, 2006 Cited by PubMed: 16973611DOI: 10.1074/jbc.M607204200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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