1T1F

Crystal Structure of Native Antithrombin in its Monomeric Form

Summary for 1T1F

Entry DOI	10.2210/pdb1t1f/pdb
Descriptor	Antithrombin-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	serine-cysteine proteinase inhibitor; thrombin; human; x-ray crystallography, blood clotting
Biological source	Homo sapiens (human)
Cellular location	Secreted, extracellular space: P01008
Total number of polymer chains	3
Total formula weight	154520.50
Authors	Johnson, D.J.D.,Huntington, J.A. (deposition date: 2004-04-16, release date: 2005-10-04, Last modification date: 2023-08-23)
Primary citation	Johnson, D.J.D.,Langdown, J.,Li, W.,Luis, S.A.,Baglin, T.P.,Huntington, J.A. Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation J.Biol.Chem., 281:35478-35486, 2006 Cited by PubMed: 16973611 DOI: 10.1074/jbc.M607204200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.75 Å)

Structure validation