PDB: 250 件ウェブページステータス検索Chemie searchBIRD

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4RIQ	Crystal structure of DPY-30 dimerization/docking domain in complex with Ash2L Sdc1-DPY-30 Interacting region (SDI) 分子名称: Protein dpy-30 homolog, SULFATE ION, Set1/Ash2 histone methyltransferase complex subunit ASH2 著者 Tremblay, V, Couture, J.-F. 登録日 2014-10-07 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.231 Å) 主引用文献 Molecular Basis for DPY-30 Association to COMPASS-like and NURF Complexes. Structure, 22, 2014
2MUM	Solution structure of the PHD domain of Yeast YNG2 分子名称: Chromatin modification-related protein YNG2, ZINC ION 著者 Taeb, S, Kaustov, L, Lemak, A, Farhadi, S, Sheng, Y. 登録日 2014-09-12 公開日 2014-12-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution structure of the PHD domain of Yeast YNG2 To be Published
4UY4	1.86 A structure of human Spindlin-4 protein in complex with histone H3K4me3 peptide 分子名称: GLYCEROL, HISTONE H3K4ME3, SPINDLIN-4 著者 Talon, R, Gileadi, C, Johansson, C, Burgess-Brown, N, Shrestha, L, von Delft, F, Krojer, T, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Oppermann, U. 登録日 2014-08-28 公開日 2014-09-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.862 Å) 主引用文献 1.86 A Structure of Human Spindlin-4 Protein in Complex with Histone H3K4Me3 Peptide To be Published
4UXN	LSD1(KDM1A)-CoREST in complex with Z-Pro derivative of MC2580 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, REST COREPRESSOR 1, ... 著者 Rodriguez, V, Valente, S, Stazi, G, Lucidi, A, Mercurio, C, Vianello, P, Ciossani, G, Mattevi, A, Botrugno, O.A, Dessanti, P, Minucci, S, Varasi, M, Mai, A. 登録日 2014-08-27 公開日 2015-02-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Pyrrole- and Indole-Containing Tranylcypromine Derivatives as Novel Lysine-Specific Demethylase 1 Inhibitors Active on Cancer Cells Chemmedchem, 6, 2015
4U7P	Crystal structure of DNMT3A-DNMT3L complex 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y. 登録日 2014-07-31 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.821 Å) 主引用文献 Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4U7T	Crystal structure of DNMT3A-DNMT3L in complex with histone H3 分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y. 登録日 2014-07-31 公開日 2014-11-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural insight into autoinhibition and histone H3-induced activation of DNMT3A Nature, 517, 2015
4QL1	Crystal structure of human WDR5 in complex with compound OICR-9429 分子名称: 1,2-ETHANEDIOL, GLYCEROL, N-(4-(4-methylpiperazin-1-yl)-3'-(morpholinomethyl)-[1,1'-biphenyl]-3-yl)-6-oxo-4-(trifluoromethyl)-1,6-dihydropyridine-3-carboxamide, ... 著者 Dong, A, Dombrovski, L, Walker, J.R, Getlik, M, Kuznetsova, E, Smil, D, Barsyte, D, Li, F, Poda, G, Senisterra, G, Marcellus, R, Al-Awar, R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2014-06-10 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Pharmacological targeting of the Wdr5-MLL interaction in C/EBP alpha N-terminal leukemia. Nat.Chem.Biol., 11, 2015
4PLI	Structure of the chromodomain of MRG2 in complex with H3K36me3 分子名称: At1g02740, H3K36me3 著者 Liu, Y, Huang, Y. 登録日 2014-05-18 公開日 2015-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.651 Å) 主引用文献 Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. Plos Genet., 10, 2014
4PLL	Structure of the chromodaomain of MRG2 in complex with H3K36me3 分子名称: At1g02740, H3K36me3 著者 Liu, Y, Huang, Y. 登録日 2014-05-18 公開日 2015-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. Plos Genet., 10, 2014
4PL6	Structure of the chromodomain of MRG2 in complex with H3K4me3 分子名称: At1g02740, H3K4me3 著者 Liu, Y.C, Huang, Y. 登録日 2014-05-16 公開日 2015-07-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.681 Å) 主引用文献 Regulation of arabidopsis flowering by the histone mark readers MRG1/2 via interaction with CONSTANS to modulate FT expression. Plos Genet., 10, 2014
4MZH	Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2s) peptide 分子名称: MAGNESIUM ION, Peptide from Histone H3.2, Spindlin-1 著者 Su, X, Ding, X, Li, H. 登録日 2013-09-30 公開日 2014-03-26 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
4MZF	Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide 分子名称: CHLORIDE ION, MAGNESIUM ION, Peptide from Histone H3.2, ... 著者 Su, X, Ding, X, Li, H. 登録日 2013-09-30 公開日 2014-03-26 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
4MZG	Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... 著者 Su, X, Ding, X, Li, H. 登録日 2013-09-30 公開日 2014-03-26 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
4C1Q	Crystal structure of the PRDM9 SET domain in complex with H3K4me2 and AdoHcy. 分子名称: GLYCEROL, HISTONE H3.1, HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9, ... 著者 Mathioudakis, N, Cusack, S, Kadlec, J. 登録日 2013-08-13 公開日 2013-10-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of Prdm9. Cell Rep., 5, 2013
4LLB	Crystal Structure of MOZ double PHD finger histone H3K14ac complex 分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-09 公開日 2013-10-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4LKA	Crystal Structure of MOZ double PHD finger histone H3K9ac complex 分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-07 公開日 2013-10-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4LK9	Crystal Structure of MOZ double PHD finger histone H3 tail complex 分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-07 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4LJN	Crystal Structure of MOZ double PHD finger 分子名称: Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-05 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4L7X	Crystal structure of the DIDO PHD finger in complex with H3K4me3 分子名称: Death-inducer obliterator 1, Histone H3 peptide, ZINC ION 著者 Tong, Q, Gatchalian, J, Kutateladze, T.G. 登録日 2013-06-14 公開日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Dido3 PHD Modulates Cell Differentiation and Division. Cell Rep, 4, 2013
4L58	Crystal structure of the MLL5 PHD finger in complex with H3K4me3 分子名称: Histone H3 peptide, Histone-lysine N-methyltransferase MLL5, ZINC ION 著者 Tong, Q, Ali, M, Kutateladze, T.G. 登録日 2013-06-10 公開日 2013-06-26 最終更新日 2013-07-24 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Molecular basis for chromatin binding and regulation of MLL5. Proc.Natl.Acad.Sci.USA, 110, 2013
2M3H	Structure of Dido PHD domain 分子名称: Death-inducer obliterator 1, ZINC ION 著者 Santiveri, C.M, Perez-Canadillas, J.M, Jimenez, M. 登録日 2013-01-19 公開日 2013-08-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NMR structure note: PHD domain from death inducer obliterator protein and its interaction with H3K4me3. J.Biomol.Nmr, 56, 2013
4II1	Crystal structure of the zinc finger of ZGPAT 分子名称: UNKNOWN ATOM OR ION, ZINC ION, Zinc finger CCCH-type with G patch domain-containing protein 著者 Bian, C, Tempel, W, Dong, A, Chao, X, Fu, M, Wernimont, A.K, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2012-12-19 公開日 2013-02-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal structure of the zinc finger of ZGPAT to be published
2M1R	PHD domain of ING4 N214D mutant 分子名称: Inhibitor of growth protein 4, ZINC ION 著者 Blanco, F.J. 登録日 2012-12-05 公開日 2012-12-26 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Functional impact of cancer-associated mutations in the tumor suppressor protein ING4. Carcinogenesis, 31, 2010
4HSU	Crystal structure of LSD2-NPAC with H3(1-26)in space group P21 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3, Lysine-specific histone demethylase 1B, ... 著者 Chen, F, Dong, Z, Fang, J, Xu, Y. 登録日 2012-10-30 公開日 2013-02-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.988 Å) 主引用文献 Structural insight into substrate recognition by histone demethylase LSD2/KDM1b. Cell Res., 23, 2013
4H75	Crystal structure of human Spindlin1 in complex with a histone H3K4(me3) peptide 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Histone H3, ... 著者 Yang, N, Wang, W, Wang, Y, Wang, M, Zhao, Q, Rao, Z, Zhu, B, Xu, R.M. 登録日 2012-09-20 公開日 2012-10-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1. Proc.Natl.Acad.Sci.USA, 109, 2012

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