PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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2FIL	Crystal Structure Analysis of the A-DNA Decamer GCGT-2'OMeA-faT-ACGC, with Incorporated 2'-O-Methylated-Adenosine (2'OMeA) and 2'-Fluoroarabino-Thymidine (faT) 分子名称: 5'-D(*GP*CP*GP*TP*(A2M)P*(TAF)P*AP*CP*GP*C)-3', COBALT HEXAMMINE(III) 著者 Egli, M, Li, F. 登録日 2005-12-29 公開日 2006-05-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. Biochemistry, 45, 2006
7YOZ	Cryo-EM structure of human subnucleosome (intermediate form) 分子名称: Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... 著者 Nozawa, K, Takizawa, Y, Kurumizaka, H. 登録日 2022-08-02 公開日 2022-11-16 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
7N9H	Structure of the mammalian importin a1 bound to the TDP-43 NLS 分子名称: Importin subunit alpha-1, TAR DNA-binding protein 43 著者 Doll, S.G, Lokareddy, R.K, Cingolani, G. 登録日 2021-06-17 公開日 2022-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta. Cell Rep, 39, 2022
5W7V	CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril 分子名称: TAR DNA-binding protein 43 著者 Guenther, E.L, Ge, P, Eisenberg, D.S. 登録日 2017-06-20 公開日 2018-03-14 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25, 2018
5WKB	MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317 分子名称: TAR DNA-binding protein 43 著者 Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. 登録日 2017-07-24 公開日 2018-05-23 最終更新日 2024-03-13 実験手法 ELECTRON CRYSTALLOGRAPHY (1 Å) 主引用文献 Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
6JRF	Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium 分子名称: CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ... 著者 Lin, Z, Lin, H, Zhang, D, Yuan, C. 登録日 2019-04-03 公開日 2019-10-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.047 Å) 主引用文献 Structural basis of sequence-specific Holliday junction cleavage by MOC1. Nat.Chem.Biol., 15, 2019
5WKD	Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 分子名称: TAR DNA-binding protein 43 著者 Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. 登録日 2017-07-25 公開日 2018-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
5WHP	Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317 分子名称: Segment of TAR DNA-binding protein 43 著者 Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. 登録日 2017-07-17 公開日 2018-05-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
5WIQ	Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402 分子名称: TAR DNA-binding protein 43 著者 Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. 登録日 2017-07-19 公開日 2018-04-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
7X58	Cryo-EM structure of human subnucleosome (open form) 分子名称: Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... 著者 Nozawa, K, Takizawa, Y, Kurumizaka, H. 登録日 2022-03-04 公開日 2022-11-16 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.93 Å) 主引用文献 Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
7X57	Cryo-EM structure of human subnucleosome (closed form) 分子名称: Histone H3.1, Histone H4, Widom601 DNA FW (145-MER), ... 著者 Nozawa, K, Takizawa, Y, Kurumizaka, H. 登録日 2022-03-04 公開日 2022-11-16 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.63 Å) 主引用文献 Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B. Proc.Natl.Acad.Sci.USA, 119, 2022
5WHN	Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317 分子名称: Segment of TAR DNA-binding protein 43 著者 Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. 登録日 2017-07-17 公開日 2018-04-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
6E8D	Crystal structure of the Bacillus subtilis sliding clamp-MutL complex. 分子名称: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL 著者 Guarne, A, Almawi, A.W. 登録日 2018-07-28 公開日 2019-05-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific. Nucleic Acids Res., 47, 2019
1AY9	WILD-TYPE UMUD' FROM E. COLI 分子名称: UMUD PROTEIN 著者 Peat, T.S, Frank, E.G, Mcdonald, J.P, Levine, A.S, Woodgate, R, Hendrickson, W.A. 登録日 1997-11-15 公開日 1998-01-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The UmuD' protein filament and its potential role in damage induced mutagenesis. Structure, 4, 1996
7AW4	MerTK kinase domain with type 3 inhibitor from a DNA-encoded library 分子名称: 1,2-ETHANEDIOL, 3-methyl-5-(4-methyl-1,2,3-thiadiazol-5-yl)-N-((R)-1-(((R)-3-(methylamino)-3-oxo-1-(4-(trifluoromethyl)phenyl)propyl)amino)-1-oxo-4-phenylbutan-2-yl)isoxazole-4-carboxamide, CHLORIDE ION, ... 著者 Pflug, A, Nissink, J.W.M, Blackett, C, Goldberg, K, Hennessy, E.J, Hardaker, E, McCoull, W, McMurray, L, Collingwood, O, Overman, R, Preston, M, Rawlins, P, Rivers, E, Schimpl, M, Smith, P, Underwood, E, Truman, C, Warwicker, J, Winter, J, Woodcock, S. 登録日 2020-11-06 公開日 2021-03-03 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy. J.Med.Chem., 64, 2021
380D	BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES 分子名称: 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*CP*GP*(G49)P*(CBR)P*CP*G)-3') 著者 Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J. 登録日 1998-02-18 公開日 1998-07-13 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes. Nucleic Acids Res., 26, 1998
4DM0	TN5 transposase: 20MER OUTSIDE END 2 MN complex 分子名称: 1,2-ETHANEDIOL, DNA NON-TRANSFERRED STRAND, DNA TRANSFERRED STRAND, ... 著者 Klenchin, V.A, Lovell, S, Goryshin, I.Y, Reznikoff, W.R, Rayment, I. 登録日 2012-02-06 公開日 2012-02-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Two-metal active site binding of a TN5 transposase synaptic complex Nat.Struct.Biol., 9, 2002
8DFA	type I-C Cascade bound to ssDNA target 分子名称: CRISPR-associated protein, CT1133 family, TM1801 family, ... 著者 O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W. 登録日 2022-06-21 公開日 2023-02-22 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural snapshots of R-loop formation by a type I-C CRISPR Cascade. Mol.Cell, 83, 2023
6AVK	Streptavidin bound to peptide-like compound KPM-6 分子名称: 1-hydroxydodecan-4-one, N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-({[(2H-1,3-benzodioxol-5-yl)methyl][2-(chloromethyl)-1,3-oxazole-4-carbonyl]amino}methyl)-N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]-1,3-oxazole-4-carboxamide, Streptavidin 著者 Park, H, Shamim, R, McEnaney, P, Kodadek, T. 登録日 2017-09-02 公開日 2018-08-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Efficient Workflow for Screening DNA-encoded One Bead One Compound Libraries Using a Flow Cytometer To be Published
6CFH	SWGMMGMLASQ segment from the low complexity domain of TDP-43 分子名称: TAR DNA-binding protein 43 著者 Guenther, E.L, Rodriguez, J.A, Sawaya, M.R, Eisenberg, D.S. 登録日 2018-02-15 公開日 2018-05-23 最終更新日 2024-05-15 実験手法 ELECTRON CRYSTALLOGRAPHY (1.5 Å) 主引用文献 Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
3HO1	Crystal structure of T. thermophilus Argonaute N546 mutant protein complexed with DNA guide strand and 12-nt RNA target strand 分子名称: 5'-D(P*TP*GP*AP*GP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*TP*AP*T*AP*GP*T)-3', 5'-R(P*CP*CP*UP*AP*CP*UP*AP*CP*CP*UP*CP*G)-3', MAGNESIUM ION, ... 著者 Wang, Y, Li, H, Sheng, G, Patel, D.J. 登録日 2009-06-01 公開日 2009-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature, 461, 2009
7Y5W	Cryo-EM structure of the left-handed Di-tetrasome 分子名称: Histone H3.1, Histone H4, Widom 601 DNA (147-MER) 著者 Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M. 登録日 2022-06-17 公開日 2023-08-16 最終更新日 2023-09-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Science, 381, 2023
2D1K	Ternary complex of the WH2 domain of mim with actin-dnase I 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Chereau, D, Kerff, F, Dominguez, R. 登録日 2005-08-26 公開日 2006-09-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the actin-binding function of missing-in-metastasis Structure, 15, 2007
5W7X	Crystal Structure of FHA domain of human APLF in complex with XRCC1 bisphospho peptide 分子名称: Aprataxin and PNK-like factor, DNA repair protein XRCC1 著者 Pedersen, L.C, Kim, K, London, R.E. 登録日 2017-06-21 公開日 2018-05-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications. Nucleic Acids Res., 45, 2017
1H15	X-ray crystal structure of HLA-DRA1*0101/DRB5*0101 complexed with a peptide from Epstein Barr Virus DNA polymerase 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA POLYMERASE, ... 著者 Lang, H, Jacobsen, H, Ikemizu, S, Andersson, C, Harlos, K, Madsen, L, Hjorth, P, Sondergaard, L, Svejgaard, A, Wucherpfennig, K, Stuart, D.I, Bell, J.I, Jones, E.Y, Fugger, L. 登録日 2002-07-02 公開日 2002-10-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A Functional and Structural Basis for Tcr Cross-Reactivity in Multiple Sclerosis Nat.Immunol., 3, 2002

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