1YKA
| Solution structure of Grx4, a monothiol glutaredoxin from E. coli. | 分子名称: | monothiol glutaredoxin ydhD | 著者 | Fladvad, M, Bellanda, M, Fernandes, A.P, Andresen, C, Mammi, S, Holmgren, A, Vlamis-Gardikas, A, Sunnerhagen, M. | 登録日 | 2005-01-17 | 公開日 | 2005-04-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular mapping of functionalities in the solution structure of reduced Grx4, a monothiol glutaredoxin from Escherichia coli. J.Biol.Chem., 280, 2005
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1YE3
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5WS7
| Crystal structure of human MTH1(G2K/C87A/C104S mutant) in complex with 2-oxo-dATP | 分子名称: | 7,8-dihydro-8-oxoguanine triphosphatase, SODIUM ION, [[(2R,3S,5R)-5-(6-azanyl-2-oxidanylidene-1H-purin-9-yl)-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | 著者 | Nakamura, T, Waz, S, Hirata, K, Nakabeppu, Y, Yamagata, Y. | 登録日 | 2016-12-05 | 公開日 | 2017-01-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Structural and Kinetic Studies of the Human Nudix Hydrolase MTH1 Reveal the Mechanism for Its Broad Substrate Specificity J. Biol. Chem., 292, 2017
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1YFM
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5WEN
| GluA2 bound to GSG1L in digitonin, state 2 | 分子名称: | Digitonin, Glutamate receptor 2,Germ cell-specific gene 1-like protein | 著者 | Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I. | 登録日 | 2017-07-10 | 公開日 | 2017-08-02 | 最終更新日 | 2021-08-25 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | Channel opening and gating mechanism in AMPA-subtype glutamate receptors. Nature, 549, 2017
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6RZX
| Carbonic Anhydrase CAIX mimic in complex with inhibitor FBSA | 分子名称: | 1,1,2,2,3,3,4,4,4-nonakis(fluoranyl)butane-1-sulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Kugler, M, Brynda, J, Rezacova, P. | 登録日 | 2019-06-13 | 公開日 | 2020-06-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Identification of Novel Carbonic Anhydrase IX Inhibitors Using High-Throughput Screening of Pooled Compound Libraries by DNA-Linked Inhibitor Antibody Assay (DIANA). SLAS Discov, 25, 2020
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5SMJ
| Trypanothione reductase | 分子名称: | BROMIDE ION, DIMETHYL SULFOXIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Fiorillo, A, Ilari, A. | 登録日 | 2022-03-05 | 公開日 | 2023-03-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design. Front Mol Biosci, 9, 2022
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3ZIQ
| minor-site specific NLS (B6) | 分子名称: | B6NLS, IMPORTIN SUBUNIT ALPHA-2 | 著者 | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | 登録日 | 2013-01-10 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
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3ZIP
| minor-site specific NLS (A58) | 分子名称: | A58NLS, IMPORTIN SUBUNIT ALPHA-2 | 著者 | Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B. | 登録日 | 2013-01-10 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha Traffic, 14, 2013
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5XIN
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5X2U
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4XR7
| Structure of the Saccharomyces cerevisiae PAN2-PAN3 core complex | 分子名称: | PAB-dependent poly(A)-specific ribonuclease subunit PAN2, PAB-dependent poly(A)-specific ribonuclease subunit PAN3 | 著者 | Schafer, I.B, Rode, M, Bonneau, F, Schussler, S, Conti, E. | 登録日 | 2015-01-20 | 公開日 | 2015-01-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.796 Å) | 主引用文献 | The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase. Nat. Struct. Mol. Biol., 21, 2014
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5X2R
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5X2T
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5XGY
| Crystal structure of peptidoglycan recognition protein (PGRP-S) at 2.45 A resolution | 分子名称: | GLYCEROL, L(+)-TARTARIC ACID, Peptidoglycan recognition protein 1 | 著者 | Shokeen, A, Sharma, P, Singh, P.K, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2017-04-18 | 公開日 | 2017-05-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal structure of peptidoglycan recognition protein (PGRP-S) at 2.45 A resolution To Be Published
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3LW8
| Shigella IpgB2 in complex with human RhoA, GDP and Mg2+ (complex A) | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, IpgB2, MAGNESIUM ION, ... | 著者 | Klink, B.U, Barden, S, Heidler, T.V, Borchers, C, Ladwein, M, Stradal, T.E.B, Rottner, K, Heinz, D.W. | 登録日 | 2010-02-23 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure of Shigella IPGB2 in complex with human RhoA: Implications for the mechanism of bacterial GEF-mimicry J.Biol.Chem., 285, 2010
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6KWW
| HslU from Staphylococcus aureus | 分子名称: | ATP-dependent protease ATPase subunit HslU | 著者 | Ha, N.-C, Jeong, S. | 登録日 | 2019-09-09 | 公開日 | 2020-07-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Cleavage-Dependent Activation of ATP-Dependent Protease HslUV from Staphylococcus aureus . Mol.Cells, 43, 2020
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7OYD
| Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | 登録日 | 2021-06-24 | 公開日 | 2022-07-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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6KR1
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1N1E
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6KPP
| BNC105 in complex with tubulin | 分子名称: | (6-methoxy-2-methyl-7-oxidanyl-1-benzofuran-3-yl)-(3,4,5-trimethoxyphenyl)methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wang, T, Wu, C, Pu, D. | 登録日 | 2019-08-15 | 公開日 | 2020-08-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.74524117 Å) | 主引用文献 | Unraveling the molecular mechanism of BNC105, a phase II clinical trial vascular disrupting agent, provides insights into drug design. Biochem.Biophys.Res.Commun., 2020
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5X2S
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3LDW
| Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound | 分子名称: | 1,2-ETHANEDIOL, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... | 著者 | Wernimont, A.K, Lew, J, Zhao, Y, Kozieradzki, I, Cossar, D, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Structural Genomics Consortium (SGC) | 登録日 | 2010-01-13 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. J.Biol.Chem., 286, 2011
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8SCD
| Crystal structure of sulfonamide resistance enzyme Sul3 in complex with reaction intermediate | 分子名称: | 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, 4-AMINOBENZOIC ACID, CHLORIDE ION, ... | 著者 | Stogios, P.J, Venkatesan, M, Michalska, K, Mesa, N, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2023-04-05 | 公開日 | 2023-05-03 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics. Nat Commun, 14, 2023
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8S9M
| DNA cytosine-N4 methyltransferase (residues 79-324) from the Bdelloid rotifer Adineta vaga | 分子名称: | 1,2-ETHANEDIOL, DNA cytosine-N4 methyltransferase, SINEFUNGIN | 著者 | Zhou, J, Horton, J.R, Cheng, X. | 登録日 | 2023-03-29 | 公開日 | 2023-08-02 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Biochemical and structural characterization of the first-discovered metazoan DNA cytosine-N4 methyltransferase from the bdelloid rotifer Adineta vaga. J.Biol.Chem., 299, 2023
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