5X2S
Direct Observation of Conformational Population Shifts in Hemoglobin: Crystal Structure of Half-Liganded Hemoglobin after Adding 4 mM bezafibrate pH 6.5.
Summary for 5X2S
| Entry DOI | 10.2210/pdb5x2s/pdb |
| Related | 5X2R 5X2T 5X2U |
| Descriptor | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING NI(II), ... (6 entities in total) |
| Functional Keywords | hemoglobin, allostery, allosteric proteins, oxygen binding, bezafibrate, transport protein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 12 |
| Total formula weight | 194020.06 |
| Authors | Ohki, M.,Park, S.-Y. (deposition date: 2017-02-02, release date: 2017-09-27, Last modification date: 2024-03-27) |
| Primary citation | Shibayama, N.,Ohki, M.,Tame, J.R.H.,Park, S.Y. Direct observation of conformational population shifts in crystalline human hemoglobin. J. Biol. Chem., 292:18258-18269, 2017 Cited by PubMed: 28931607DOI: 10.1074/jbc.M117.781146 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
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