PDB: 72236 件ウェブページステータス検索Chemie searchBIRD

---

7KKC	Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to 5-Hydroxyindoleacetic acid 分子名称: (5-hydroxy-1H-indol-3-yl)acetic acid, SULFATE ION, Transcriptional regulator, ... 著者 Walton, W.G, Redinbo, M.R, Dangl, J.L. 登録日 2020-10-27 公開日 2021-12-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
7KJL	Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to Salicylic acid 分子名称: 2-HYDROXYBENZOIC ACID, SULFATE ION, Transcriptional regulator, ... 著者 Walton, W.G, Redinbo, M.R, Dangl, J.L. 登録日 2020-10-26 公開日 2021-12-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
6AR4	Crystal structure of PICK1 in complex with the small molecule inhibitor 1o 分子名称: N-[4-(4-bromophenyl)-1-{[2-(trifluoromethyl)phenyl]methyl}piperidine-4-carbonyl]-3-cyclopropyl-L-alanine, PRKCA-binding protein 著者 Marcotte, D. 登録日 2017-08-21 公開日 2018-08-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction. Sci Rep, 8, 2018
6ARC	Monoclinic EutL - structure determined from merged "Group 1" data 分子名称: CHLORIDE ION, Ethanolamine utilization protein, SODIUM ION 著者 Thompson, M.C, Cascio, D, Yeates, T.O. 登録日 2017-08-22 公開日 2017-10-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta Crystallogr D Struct Biol, 74, 2018
7KRH	Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus with S28A and R46A mutations 分子名称: SULFATE ION, Transcriptional regulator, MarR family 著者 Walton, W.G, Redinbo, M.R, Dangl, J.L. 登録日 2020-11-19 公開日 2021-12-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
7KKI	Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to 2,4-Dichlorophenoxyacetic acid 分子名称: (2,4-DICHLOROPHENOXY)ACETIC ACID, SULFATE ION, Transcriptional regulator, ... 著者 Walton, W.G, Redinbo, M.R, Dangl, J.L. 登録日 2020-10-27 公開日 2021-12-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
7KIG	Crystal structure of the MarR family transcriptional regulator from Variovorax paradoxus bound to Indole-3-butyric acid 分子名称: 3-INDOLEBUTYRIC ACID, SULFATE ION, Transcriptional regulator, ... 著者 Walton, W.G, Redinbo, M.R, Dangl, J.L. 登録日 2020-10-23 公開日 2021-12-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
1SCA	ENZYME CRYSTAL STRUCTURE IN A NEAT ORGANIC SOLVENT 分子名称: CALCIUM ION, SODIUM ION, SUBTILISIN CARLSBERG 著者 Fitzpatrick, P.A, Steinmetz, A.C.U, Ringe, D, Klibanov, A.M. 登録日 1993-07-19 公開日 1994-01-31 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Enzyme crystal structure in a neat organic solvent. Proc.Natl.Acad.Sci.USA, 90, 1993
6B5X	Beta-Lactamase, unmixed shards crystal form 分子名称: Beta-lactamase, PHOSPHATE ION 著者 Pandey, S. 登録日 2017-09-29 公開日 2018-06-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography. BMC Biol., 16, 2018
7KYM	Crystal structure of the MarR family transcriptional regulator from Bradyrhizobium japonicum 分子名称: MarR family transcriptional regulator, PHOSPHATE ION 著者 Walton, W.G, Redinbo, M.R, Dangl, J.L. 登録日 2020-12-08 公開日 2021-12-15 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
6B6F	Beta-Lactamase, mixed with Ceftriaxone, needles crystal form, 2sec 分子名称: Beta-lactamase, Ceftriaxone 著者 Pandey, S, Schmidt, M. 登録日 2017-10-01 公開日 2018-06-27 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography. BMC Biol., 16, 2018
6B97	Crystal structure of PDE2 in complex with complex 9 分子名称: 1,2-ETHANEDIOL, 6-chloro-1-methyl-N-{(1R)-1-[4-(trifluoromethyl)phenyl]ethyl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine, MAGNESIUM ION, ... 著者 Lu, J. 登録日 2017-10-10 公開日 2017-11-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 The identification of a novel lead class for phosphodiesterase 2 inhibition by fragment-based drug design. Bioorg. Med. Chem. Lett., 27, 2017
6BA2	Crystal structure of MYST acetyltransferase domain in complex with inhibitor 分子名称: 4-fluoro-5-methyl-N'-(phenylsulfonyl)[1,1'-biphenyl]-3-carbohydrazide, CHLORIDE ION, GLYCEROL, ... 著者 Hermans, S.J, Chung, M.C, Peat, T.S, Baell, J.B, Thomas, T, Parker, M.W. 登録日 2017-10-11 公開日 2018-08-01 最終更新日 2020-01-08 実験手法 X-RAY DIFFRACTION (1.85003817 Å) 主引用文献 Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. Nature, 560, 2018
6USX	Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer 分子名称: 1-{4-[2-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}-7-(naphthalen-1-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl}propan-1-one, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Vigers, G.P, Smith, D.J. 登録日 2019-10-28 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Identification of the Clinical Development CandidateMRTX849, a Covalent KRASG12CInhibitor for the Treatment of Cancer. J.Med.Chem., 63, 2020
6UXF	Structure of V. metoecus NucC, hexamer form 分子名称: Vibrio meotecus sp. RC341 NucC 著者 Ye, Q, Corbett, K.D. 登録日 2019-11-07 公開日 2019-12-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity. Mol.Cell, 77, 2020
7L19	Crystal structure of the MarR family transcriptional regulator from Enterobacter soli strain LF7 bound to Indole 3 acetic acid 分子名称: 1H-INDOL-3-YLACETIC ACID, MarR family transcriptional regulator, NICKEL (II) ION 著者 Lietzan, A.D, Walton, W.G, Redinbo, M.R, Dangl, J.L. 登録日 2020-12-14 公開日 2021-12-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
6Y8F	An inactive (D136N and D137N) variant of alpha-1,6-mannanase, GH76A of Salegentibacter sp. HEL1_6 in complex with alpha-1,6-mannotriose 分子名称: Alpha-1,6-endo-mannanase GH76A mutant, CALCIUM ION, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose 著者 Hehemann, J.H, Solanki, V.A. 登録日 2020-03-04 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.472 Å) 主引用文献 Glycoside hydrolase from the GH76 family indicates that marine Salegentibacter sp. Hel_I_6 consumes alpha-mannan from fungi. Isme J, 2022
7L1I	Crystal structure of the MarR family transcriptional regulator from Acineotobacter baumannii bound to Indole 3 acetic acid 分子名称: 1H-INDOL-3-YLACETIC ACID, MarR family multidrug resistance pump transcriptional regulator, NICKEL (II) ION 著者 Walton, W.G, Lietzan, A.D, Redinbo, M.R, Dangl, J.L. 登録日 2020-12-14 公開日 2022-02-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
7KQL	Anti-Tim3 antibody Fab complex 分子名称: GLYCEROL, Hepatitis A virus cellular receptor 2, Tim3.18 Fab heavy chain, ... 著者 Deng, X.A, West, S.M, Strop, P. 登録日 2020-11-16 公開日 2022-02-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Tim-3 mediates T cell trogocytosis to limit antitumor immunity. J.Clin.Invest., 132, 2022
6MJ6	Crystal structure of the mCD1d/xxx (JJ166) /iNKTCR ternary complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Zajonc, D.M, Bitra, A, Janssens, J. 登録日 2018-09-20 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies. ChemMedChem, 14, 2019
6AXZ	Segment from bank vole prion protein 168-176 QYNNQNNFV 分子名称: Major prion protein 著者 Glynn, C, Rodriguez, J.A, Boyer, D.R, Gallagher-Jones, M. 登録日 2017-09-07 公開日 2018-01-17 最終更新日 2024-03-13 実験手法 ELECTRON CRYSTALLOGRAPHY (0.75 Å) 主引用文献 Sub-angstrom cryo-EM structure of a prion protofibril reveals a polar clasp. Nat. Struct. Mol. Biol., 25, 2018
6MGN	mouse Id1 (51-104) - human hE47 (348-399) complex 分子名称: DNA-binding protein inhibitor ID-1, Transcription factor E2-alpha 著者 Benezra, R, Pavletich, N.P, Gall, A.-L, Goldgur, Y. 登録日 2018-09-14 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep, 29, 2019
6V4J	Structure of TrkH-TrkA in complex with ATP 分子名称: Potassium uptake protein TrkA, Trk system potassium uptake protein TrkH 著者 Zhou, M, Zhang, H. 登録日 2019-11-27 公開日 2020-02-12 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun, 11, 2020
6MGM	Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1 分子名称: DNA-binding protein inhibitor ID-1 著者 Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L. 登録日 2018-09-14 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.791 Å) 主引用文献 A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep, 29, 2019
1RP1	DOG PANCREATIC LIPASE RELATED PROTEIN 1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PANCREATIC LIPASE RELATED PROTEIN 1 著者 Roussel, A, Cambillau, C. 登録日 1998-04-02 公開日 1998-06-17 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Reactivation of the totally inactive pancreatic lipase RP1 by structure-predicted point mutations. Proteins, 32, 1998

<588589590591592593594595596597598599600601602603>