PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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6NPD	X-ray crystal structure of TmpA, 2-trimethylaminoethylphosphonate hydroxylase, with Fe, 2OG, and (R)-1-hydroxy-2-trimethylaminoethylphosphonate 分子名称: (2R)-2-hydroxy-N,N,N-trimethyl-2-phosphonoethan-1-aminium, FE (II) ION, TmpA, ... 著者 Rajakovich, L.J, Mitchell, A.J, Boal, A.K. 登録日 2019-01-17 公開日 2019-03-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 A New Microbial Pathway for Organophosphonate Degradation Catalyzed by Two Previously Misannotated Non-Heme-Iron Oxygenases. Biochemistry, 58, 2019
6CEI	Solution NMR Structure of Conotoxin GXIA from Conus geographus 分子名称: GXIA 著者 Armstrong, D.A, Rosengren, K.J. 登録日 2018-02-12 公開日 2018-03-07 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus . Mar Drugs, 19, 2021
8BA5	Crystal structure of the DNMT3A ADD domain 分子名称: 1,2-ETHANEDIOL, DNA (cytosine-5)-methyltransferase 3A, MAGNESIUM ION, ... 著者 Linhard, V, Kunert, S, Wollenhaupt, J, Broehm, A, Schwalbe, H, Jeltsch, A. 登録日 2022-10-11 公開日 2022-11-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site. Protein Sci., 32, 2023
8H0I	Cryo-EM structure of APOBEC3G-Vif complex 分子名称: APOBEC3G, CHLORIDE ION, Core binding factor beta, ... 著者 Kouno, T, Shibata, S, Hyun, J, Kim, T.G, Wolf, M. 登録日 2022-09-29 公開日 2023-07-19 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural insights into RNA bridging between HIV-1 Vif and antiviral factor APOBEC3G. Nat Commun, 14, 2023
7VMB	Crystal structure of IQSEC1-IQ motif, Sec7PH tandem in complex with calmodulin 分子名称: Calmodulin-1, GLYCEROL, IQ motif and SEC7 domain-containing protein 1 著者 Yang, W, Zhang, M. 登録日 2021-10-08 公開日 2022-10-12 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.99777377 Å) 主引用文献 Ca2+-induced release of IQSEC2/BRAG1 autoinhibition under physiological and pathological conditions. J.Cell Biol., 222, 2023
5NQ8	Crystal structure of laccases from Pycnoporus sanguineus, izoform II 分子名称: 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, COPPER (II) ION, Laccase, ... 著者 Orlikowska, M, de J.Rostro-Alanis, M, Bujacz, A, Hernandez-Luna, C, Rubio, R, Parra, R, Bujacz, G. 登録日 2017-04-19 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural studies of two thermostable laccases from the white-rot fungus Pycnoporus sanguineus. Int. J. Biol. Macromol., 107, 2018
6VVN	F6 fused 4-OT wild type asymmetric trimer 分子名称: 4-oxalocrotonate tautomerase, GLYCEROL 著者 Medellin, B.P, Whitman, C.P, Zhang, Y.J. 登録日 2020-02-18 公開日 2020-04-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.39 Å) 主引用文献 Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer. Biochemistry, 59, 2020
6ZBI	Ternary complex of Calmodulin bound to 2 molecules of NHE1 分子名称: CALCIUM ION, Calmodulin-1, Sodium/hydrogen exchanger 1 著者 Prestel, A, Kragelund, B.B, Pedersen, E.S, Pedersen, S.F, Sjoegaard-Frich, L.M. 登録日 2020-06-08 公開日 2021-03-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Dynamic Na + /H + exchanger 1 (NHE1) - calmodulin complexes of varying stoichiometry and structure regulate Ca 2+ -dependent NHE1 activation. Elife, 10, 2021
6CNM	Cryo-EM structure of the human SK4/calmodulin channel complex 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Calmodulin-1, DODECYL-BETA-D-MALTOSIDE, ... 著者 Lee, C.H, MacKinnon, R. 登録日 2018-03-08 公開日 2018-05-02 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Science, 360, 2018
2K9R	Enhancing the activity of insulin by stereospecific unfolding 分子名称: Insulin 著者 Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A. 登録日 2008-10-23 公開日 2008-11-11 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS. J.Biol.Chem., 284, 2009
6NYV	Structure of spastin AAA domain in complex with a quinazoline-based inhibitor 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, N-(3-tert-butyl-1H-pyrazol-5-yl)-2-[(2R)-2-methylpiperazin-1-yl]quinazolin-4-amine, SULFATE ION, ... 著者 Pisa, R, Cupido, T, Kapoor, T.M. 登録日 2019-02-12 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.425 Å) 主引用文献 Designing Allele-Specific Inhibitors of Spastin, a Microtubule-Severing AAA Protein. J. Am. Chem. Soc., 141, 2019
6VVD	Legionella pneumophila Lpg2603 kinase bound to IP6 分子名称: Dot/Icm T4SS effector, INOSITOL HEXAKISPHOSPHATE 著者 Tomchick, D.R, Tagliabracci, V.S, Sreelatha, A. 登録日 2020-02-17 公開日 2020-04-08 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 ALegionellaeffector kinase is activated by host inositol hexakisphosphate. J.Biol.Chem., 295, 2020
6W8J	Structure of DNMT3A (R882H) in complex with CAG DNA 分子名称: CAG DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, ... 著者 Anteneh, H, Song, J. 登録日 2020-03-20 公開日 2020-04-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.445 Å) 主引用文献 Structural basis for impairment of DNA methylation by the DNMT3A R882H mutation. Nat Commun, 11, 2020
6VZF	Crystal Structure of Atg11 Coiled-Coil 3 分子名称: Autophagy-related protein 11, SULFATE ION 著者 Margolis, H.K, Ragusa, M.J. 登録日 2020-02-28 公開日 2020-09-16 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 The Third Coiled Coil Domain of Atg11 Is Required for Shaping Mitophagy Initiation Sites. J.Mol.Biol., 432, 2020
4WUM	X-ray crystal structure of Chalcone Synthase from Freesia hybrida 分子名称: Chalcone synthase 著者 Almqvist, J, Jiang, W.S, Wang, L, Huang, Y. 登録日 2014-11-02 公開日 2014-11-12 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Molecular and Biochemical Analysis of Chalcone Synthase from Freesia hybrid in Flavonoid Biosynthetic Pathway. Plos One, 10, 2015
2K91	Enhancing the activity of insulin by stereospecific unfolding 分子名称: Insulin 著者 Hua, Q.X, Xu, B, Huang, K, Hu, S.Q, Nakarawa, S, Jia, W.H, Philips, N.F.P, Wittaker, L, Wittaker, J, Katsoyannis, P.G, Weiss, M.A. 登録日 2008-09-29 公開日 2008-11-18 最終更新日 2021-10-20 実験手法 SOLUTION NMR 主引用文献 Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS. J.Biol.Chem., 284, 2009
1KFK	Crystal structure of Tryptophan Synthase From Salmonella Typhimurium 分子名称: PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, TRYPTOPHAN SYNTHASE ALPHA CHAIN, ... 著者 Kulik, V, Weyand, M, Seidel, R, Niks, D, Arac, D, Dunn, M.F, Schlichting, I. 登録日 2001-11-21 公開日 2003-10-21 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 On the role of alphaThr183 in the allosteric regulation and catalytic mechanism of tryptophan synthase. J.Mol.Biol., 324, 2002
1KEY	Crystal Structure of Mouse Testis/Brain RNA-binding Protein (TB-RBP) 分子名称: translin 著者 Pascal, J.M, Hart, P.J, Hecht, N.B, Robertus, J.D. 登録日 2001-11-19 公開日 2002-07-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Crystal Structure of TB-RBP, a Novel RNA-binding and Regulating Protein J.Mol.Biol., 319, 2002
5KDM	Crystal structure of EBV tegument protein BNRF1 in complex with histone chaperone DAXX and histones H3.3-H4 分子名称: Death domain-associated protein 6, Histone H3.3, Histone H4, ... 著者 Huang, H, Patel, D. 登録日 2016-06-08 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural basis underlying viral hijacking of a histone chaperone complex. Nat Commun, 7, 2016
8FC7	Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK2798745 分子名称: 1-({(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl}methyl)-1H-benzimidazole-6-carbonitrile, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Kwon, D.H, Lee, S.-Y, Zhang, F. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. Nat Commun, 14, 2023
8FZZ	Phocaeicola vulgatus type VI secretion system Ntox15 effector and immunity Tde2/Tdi2 分子名称: DUF1851 domain-containing protein, Ntox15 domain-containing protein 著者 Bosch, D.E, Mougous, J.D. 登録日 2023-01-30 公開日 2023-07-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Structural disruption of Ntox15 nuclease effector domains by immunity proteins protects against type VI secretion system intoxication in Bacteroidales. Mbio, 14, 2023
8FC9	Cryo-EM structure of the human TRPV4 - RhoA, apo condition 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA, ... 著者 Kwon, D.H, Lee, S.-Y, Zhang, F. 登録日 2022-12-01 公開日 2023-07-12 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease. Nat Commun, 14, 2023
2H7G	Structure of variola topoisomerase non-covalently bound to DNA 分子名称: 5'-D(*TP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*TP*TP*GP*TP*CP*GP*CP*CP*CP*TP*TP*A)-3', DNA topoisomerase 1 著者 Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. 登録日 2006-06-02 公開日 2006-08-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for specificity in the poxvirus topoisomerase. Mol.Cell, 23, 2006
1KQB	Structure of Nitroreductase from E. cloacae complex with inhibitor benzoate 分子名称: BENZOIC ACID, FLAVIN MONONUCLEOTIDE, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE 著者 Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W. 登録日 2002-01-04 公開日 2002-02-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structures of nitroreductase in three states: effects of inhibitor binding and reduction. J.Biol.Chem., 277, 2002
1KV5	Structure of Trypanosoma brucei brucei TIM with the salt-bridge-forming residue Arg191 mutated to Ser 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-PHOSPHOGLYCOLIC ACID, GLYCEROL, ... 著者 Kursula, I, Partanen, S, Lambeir, A.-M, Wierenga, R.K. 登録日 2002-01-25 公開日 2002-03-29 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The importance of the conserved Arg191-Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis FEBS Lett., 518, 2002

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