4F1F
 
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-06 | | 公開日 | 2013-05-08 | | 最終更新日 | 2013-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.684 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4F8F
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-17 | | 公開日 | 2013-05-22 | | 最終更新日 | 2013-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.676 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4F1D
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-06 | | 公開日 | 2013-05-08 | | 最終更新日 | 2013-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.637 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4DWX
 | | Crystal Structure of a Family GH-19 Chitinase from rye seeds | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Basic endochitinase C, SULFATE ION, ... | | 著者 | Numata, T, Umemoto, N, Ohnuma, T, Fukamizo, T. | | 登録日 | 2012-02-27 | | 公開日 | 2012-08-15 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure and chitin oligosaccharide-binding mode of a 'loopful' family GH19 chitinase from rye, Secale cereale, seeds
Febs J., 279, 2012
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4F4V
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-11 | | 公開日 | 2013-05-15 | | 最終更新日 | 2013-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.637 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4F51
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-11 | | 公開日 | 2013-05-15 | | 最終更新日 | 2013-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.637 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4EWZ
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-04-29 | | 公開日 | 2013-05-01 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.791 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4F1C
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-06 | | 公開日 | 2013-05-08 | | 最終更新日 | 2013-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4F1B
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-06 | | 公開日 | 2013-05-08 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.591 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4F1G
 | | Human insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-06 | | 公開日 | 2013-05-08 | | 最終更新日 | 2013-12-18 | | 実験手法 | X-RAY DIFFRACTION (1.637 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4FG3
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4EX1
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-04-29 | | 公開日 | 2013-05-01 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.657 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4EY9
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-01 | | 公開日 | 2013-05-01 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.471 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4EYD
 | | Human Insulin | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | | 登録日 | 2012-05-01 | | 公開日 | 2013-05-01 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.471 Å) | | 主引用文献 | Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85, 2013
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4G6J
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4FXE
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4G5Z
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6QGK
 | | Structure of human Bcl-2 in complex with THIQ-phenyl pyrazole compound | | 分子名称: | 1-[2-[[(3~{S})-3-(aminomethyl)-3,4-dihydro-1~{H}-isoquinolin-2-yl]carbonyl]phenyl]-~{N},~{N}-dibutyl-5-methyl-pyrazole-3-carboxamide, ACETATE ION, Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1 | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6QGD
 | | Structure of human Mcl-1 in complex with thienopyrimidine inhibitor | | 分子名称: | 2-[(6-ethyl-5-phenyl-thieno[2,3-d]pyrimidin-4-yl)amino]-3-oxidanyl-propanoic acid, Maltose-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ... | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6QGG
 | | Structure of human Bcl-2 in complex with analogue of ABT-737 | | 分子名称: | Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1, [(3~{R})-3-[[4-[[4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]phenyl]carbonylsulfamoyl]-2-nitro-phenyl]amino]-4-phenylsulfanyl-butyl]-(2-hydroxy-2-oxoethyl)-dimethyl-azanium | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6QFI
 | | Structure of human Mcl-1 in complex with BIM BH3 peptide | | 分子名称: | Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1, ZINC ION | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6QFQ
 | | Structure of human Mcl-1 in complex with indole acid inhibitor | | 分子名称: | 7-(3,5-dimethyl-1~{H}-pyrazol-4-yl)-3-(3-naphthalen-1-yloxypropyl)-1~{H}-indole-2-carboxylic acid, Induced myeloid leukemia cell differentiation protein Mcl-1 | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6QG8
 | | Structure of human Bcl-2 in complex with PUMA BH3 peptide | | 分子名称: | Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1, Bcl-2-binding component 3 | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6QFM
 | | Structure of human Mcl-1 in complex with PUMA BH3 peptide | | 分子名称: | Bcl-2-binding component 3, CHLORIDE ION, Induced myeloid leukemia cell differentiation protein Mcl-1, ... | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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6QGH
 | | Structure of human Bcl-2 in complex with ABT-263 | | 分子名称: | 4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide, Apoptosis regulator Bcl-2,Bcl-2-like protein 1,Apoptosis regulator Bcl-2,Bcl-2-like protein 1 | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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