PDB: 12060 件ウェブページステータス検索Chemie searchBIRD

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7DHK	The co-crystal structure of DYRK2 with a small molecule inhibitor 13 分子名称: 2-methoxy-7-phenylmethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-16 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.341 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DHV	The co-crystal structure of DYRK2 with a small molecule inhibitor 8 分子名称: 2,7-dimethoxy-9-(piperidin-4-ylmethylsulfanyl)acridine-4-carboxylic acid, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Wei, T, Xiao, J. 登録日 2020-11-17 公開日 2021-11-17 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.679 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DJO	The co-crystal structure of DYRK2 with a small molecule inhibitor 17 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3S)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol 著者 Wei, T, Xiao, J. 登録日 2020-11-20 公開日 2021-11-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.499 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
7DL6	The co-crystal structure of DYRK2 with a small molecule inhibitor 18 分子名称: Dual specificity tyrosine-phosphorylation-regulated kinase 2, [2,7-dimethoxy-9-[[(3R)-pyrrolidin-3-yl]methylsulfanyl]acridin-4-yl]methanol 著者 Wei, T, Xiao, J. 登録日 2020-11-26 公開日 2021-12-01 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.648 Å) 主引用文献 Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry. Elife, 11, 2022
4IGK	Structure of human BRCA1 BRCT in complex with ATRIP peptide 分子名称: ATRIP peptide, Breast cancer type 1 susceptibility protein, GLYCEROL 著者 Liu, X, Ladias, J.A.A. 登録日 2012-12-17 公開日 2013-10-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1. Biochemistry, 52, 2013
2JAU	Crystal structure of D41N variant of human mitochondrial 5'(3')- deoxyribonucleotidase (mdN) in complex with 3'-azidothymidine 5'- monophosphate 分子名称: 3'-AZIDO-3'-DEOXYTHYMIDINE-5'-MONOPHOSPHATE, 5'(3')-DEOXYRIBONUCLEOTIDASE, MAGNESIUM ION, ... 著者 Wallden, K, Ruzzenente, B, Bianchi, V, Nordlund, P. 登録日 2006-11-30 公開日 2007-12-11 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of Human and Murine Deoxyribonucleotidases: Insights Into Recognition of Substrates and Nucleotide Analogues. Biochemistry, 46, 2007
5ZTN	The crystal structure of human DYRK2 in complex with Curcumin 分子名称: (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, Dual specificity tyrosine-phosphorylation-regulated kinase 2 著者 Ji, C.G, Xiao, J.Y. 登録日 2018-05-04 公開日 2018-07-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.496 Å) 主引用文献 Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6ZWK	Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody) 分子名称: CHLORIDE ION, Histone H2AX, SODIUM ION, ... 著者 McEwen, A.G, Moeglin, E, Desplancq, D, Weiss, E, Poterszman, A. 登録日 2020-07-28 公開日 2021-07-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A Novel Nanobody Precisely Visualizes Phosphorylated Histone H2AX in Living Cancer Cells under Drug-Induced Replication Stress. Cancers (Basel), 13, 2021
5MNJ	Structure of MDM2-MDMX-UbcH5B-ubiquitin complex 分子名称: E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, Protein Mdm4, ... 著者 Klejnot, M, Huang, D.T. 登録日 2016-12-13 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.16 Å) 主引用文献 Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity. Nat. Struct. Mol. Biol., 24, 2017
8Q1Y	Outward-facing, open2 proteoliposome complex I at 2.6 A, after deactivation treatment. Initially purified in LMNG. 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Grba, D.N, Hirst, J. 登録日 2023-08-01 公開日 2024-06-05 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
8Q25	Outward-facing, open1 proteoliposome complex I at 2.8 A, after deactivation treatment. Initially purified in LMNG. 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Grba, D.N, Hirst, J. 登録日 2023-08-01 公開日 2024-06-05 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
8Q1U	Inward-facing, open1 proteoliposome complex I at 3.3 A, after deactivation treatment. Initially purified in LMNG. 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Grba, D.N, Hirst, J. 登録日 2023-08-01 公開日 2024-06-05 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
8Q1P	Inward-facing, open2 proteoliposome complex I at 2.9 A, after deactivation treatment. Initially purified in LMNG. 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Grba, D.N, Hirst, J. 登録日 2023-08-01 公開日 2024-06-05 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I. Science, 384, 2024
4UXA	Improved variant of (R)-selective manganese-dependent hydroxynitrile lyase from bacteria 分子名称: CUPIN 2 CONSERVED BARREL DOMAIN PROTEIN, MANGANESE (II) ION 著者 Pavkov-Keller, T, Wiedner, R, Kothbauer, B, Gruber-Khadjawi, M, Schwab, H, Steiner, K, Gruber, K. 登録日 2014-08-21 公開日 2015-01-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Improving the Properties of Bacterial R-Selective Hydroxynitrile Lyases for Industrial Applications Chemcatchem, 2015
3DQ1	Structure of the Yellow Fluorescent Protein Citrine Frozen at 4000 Atmospheres Number 2: Structure 24 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQA	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1250 Atmospheres Number 4: Structure 14 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQ6	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1920 Atmospheres Number 2: Structure 18 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQL	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1000 Atmospheres Number 1: Structure 5 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQ3	Structure of the Yellow Fluorescent Protein Citrine Frozen at 2500 Atmospheres: Structure 22 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQD	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1250 Atmospheres Number 2: Structure 12 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQN	Structure of the Yellow Fluorescent Protein Citrine Frozen at 500 Atmospheres: Structure 3 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
5N84	TTK kinase domain in complex with Mps-BAY2b 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, Dual specificity protein kinase TTK, SODIUM ION, ... 著者 Uitdehaag, J, Willemsen-Seegers, N, de Man, J, Buijsman, R.C, Zaman, G.J.R. 登録日 2017-02-22 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Target Residence Time-Guided Optimization on TTK Kinase Results in Inhibitors with Potent Anti-Proliferative Activity. J. Mol. Biol., 429, 2017
3DQH	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1000 Atmospheres Number 5: Structure 9 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQ9	Structure of the Yellow Fluorescent Protein Citrine Frozen at 1500 Atmospheres Number 1: Structure 15 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008
3DQM	Structure of the Yellow Fluorescent Protein Citrine Frozen at 750 Atmospheres: Structure 4 in a Series of 26 High Pressure Structures 分子名称: Green fluorescent protein 著者 Barstow, B, Kim, C.U. 登録日 2008-07-09 公開日 2008-09-23 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Alteration of citrine structure by hydrostatic pressure explains the accompanying spectral shift. Proc.Natl.Acad.Sci.Usa, 105, 2008

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