8Q25

Outward-facing, open1 proteoliposome complex I at 2.8 A, after deactivation treatment. Initially purified in LMNG.

Summary for 8Q25

• Entry DOI: 10.2210/pdb8q25/pdb
• Related: 8Q1P 8Q1U 8Q1Y
• EMDB information: 18066 18067 18068 18069
• Descriptor: NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (60 entities in total)
• Functional Keywords: complex i, oxidoreductase, proteoliposomes, membrane-bound, metabolism, membrane protein
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 45
• Total formula weight: 1104242.89

Authors

Grba, D.N.,Hirst, J. (deposition date: 2023-08-01, release date: 2024-06-05)

• Primary citation: Grba, D.N.,Wright, J.J.,Fisher, W.,Yin, Z.,Hirst, J.; Structure of complex I embedded in liposomes reveals mechanism of active/deactive transition; Science, 2024; DOI: 10.1126/science.ado2075

Experimental method

ELECTRON MICROSCOPY (2.8 Å)