PDB: 237423 件ウェブページステータス検索Chemie searchBIRD

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6DEI	Structure of Dse3-Csm1 complex 分子名称: ACETATE ION, Monopolin complex subunit CSM1, Protein DSE3, ... 著者 Singh, N, Corbett, K.D. 登録日 2018-05-12 公開日 2018-10-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 The budding-yeast RWD protein Csm1 scaffolds diverse protein complexes through a conserved structural mechanism. Protein Sci., 27, 2018
6DEJ	The structure of HcRed7, a brighter and red-shifted HcRed variant 分子名称: CHLORIDE ION, DODECAETHYLENE GLYCOL, GFP-like non-fluorescent chromoprotein, ... 著者 Wannier, T.M, Mayo, S.L. 登録日 2018-05-12 公開日 2018-05-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.6279 Å) 主引用文献 Monomerization of far-red fluorescent proteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DEK	Crystal structure of Candida albicans acetohydroxyacid synthase catalytic subunit 分子名称: Acetolactate synthase, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.971 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DEL	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide chlorimuron ethyl 分子名称: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, (3Z)-4-{[(4-amino-2-methylpyrimidin-5-yl)methyl](formyl)amino}-3-sulfanylpent-3-en-1-yl trihydrogen diphosphate, 2-[[[[(4-CHLORO-6-METHOXY-2-PYRIMIDINYL)AMINO]CARBONYL]AMINO]SULFONYL]BENZOIC ACID ETHYL ESTER, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.119 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DEM	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide bensulfuron methyl 分子名称: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.038 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DEN	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron ethyl 分子名称: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, CARBON DIOXIDE, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.806 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DEO	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide iodomuron methyl 分子名称: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, CARBON DIOXIDE, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.971 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DEP	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide sulfometuron methyl 分子名称: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.149 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DEQ	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide penoxsulam 分子名称: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, 2-(2,2-difluoroethoxy)-N-(5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-yl)-6-(trifluoromethyl)benzenesulfonamide, Acetolactate synthase, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.127 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DER	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide metosulam 分子名称: (3Z)-4-{[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]AMINO}-3-MERCAPTOPENT-3-EN-1-YL TRIHYDROGEN DIPHOSPHATE, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.126 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DES	Crystal structure of Candida albicans acetohydroxyacid synthase in complex with the herbicide propoxycarbazone 分子名称: 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Garcia, M.D, Guddat, L.W. 登録日 2018-05-12 公開日 2018-09-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.402 Å) 主引用文献 Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DET	The crystal structure of Tv2483 bound to L-arginine 分子名称: ARGININE, Tv2483 著者 Brautigam, C.A, Norgard, M.V. 登録日 2018-05-13 公開日 2019-03-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Biophysical insights into a highly selective l-arginine-binding lipoprotein of a pathogenic treponeme. Protein Sci., 27, 2018
6DEU	Human caspase-6 A109T 分子名称: Caspase-6 著者 Tubeleviciute-Aydin, A, Beautrait, A, Lynham, J, Sharma, G, Gorelik, A, Deny, L.J, Soya, N, Lukacs, G.L, Nagar, B, Marinier, A, LeBlanc, A.C. 登録日 2018-05-13 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.796 Å) 主引用文献 Identification of Allosteric Inhibitors against Active Caspase-6. Sci Rep, 9, 2019
6DEV	Human caspase-6 E35K 分子名称: Caspase-6 著者 Tubeleviciute-Aydin, A, Beautrait, A, Lynham, J, Sharma, G, Gorelik, A, Deny, L.J, Soya, N, Lukacs, G.L, Nagar, B, Marinier, A, LeBlanc, A.C. 登録日 2018-05-13 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.348 Å) 主引用文献 Identification of Allosteric Inhibitors against Active Caspase-6. Sci Rep, 9, 2019
6DEW	Structure of human COQ9 protein with bound isoprene. 分子名称: (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, (2Z,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, ... 著者 Bingman, C.A, Lohman, D.C, Smith, R.W, Pagliarini, D.J. 登録日 2018-05-13 公開日 2019-02-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Isoprene Lipid-Binding Protein Promotes Eukaryotic Coenzyme Q Biosynthesis. Mol.Cell, 73, 2019
6DEX	Structure of Eremothecium gossypii Shu1:Shu2 complex 分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, MAGNESIUM ION, Suppressor of hydroxyurea sensitivity protein 1, ... 著者 Singh, N, Corbett, K.D. 登録日 2018-05-13 公開日 2018-05-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of Eremothecium gossypii Shu1:Shu2 complex To Be Published
6DEY	Aspartylglucosaminuria mutant structure and function 分子名称: Glycosylasparaginase, residues 188-331, residues 38-178 著者 Pande, S, Laksminarasimhan, D, Guo, H.C. 登録日 2018-05-13 公開日 2018-08-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Biochemical and structural insights into an allelic variant causing the lysosomal storage disorder - aspartylglucosaminuria. FEBS Lett., 592, 2018
6DEZ	Anti-phosphotyrosine antibody PY20-4D5 Fab complexed with sulfate 分子名称: Anti-phosphotyrosine antibody PY20-4D5 heavy chain, Anti-phosphotyrosine antibody PY20-4D5 light chain, SULFATE ION 著者 Mou, K, Leung, K, Wells, J.A. 登録日 2018-05-13 公開日 2018-11-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J. Am. Chem. Soc., 140, 2018
6DF0	anti-phosphotyrosine antibody 4G10-4D5 Fab complexed with sulfate 分子名称: 4G10-4D5 Antibody Light chain, 4G10-4D5 Antibody heavy chain, SULFATE ION 著者 Mou, K, Leung, K, Wells, J.A. 登録日 2018-05-13 公開日 2018-11-28 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J. Am. Chem. Soc., 140, 2018
6DF1	Anti-phosphotyrosine antibody 4G10-4D5 Fab complexed with phosphotyrosine peptide 分子名称: Anti-phosphotyrosine antibody 4G10-4D5 heavy chain, Anti-phosphotyrosine antibody 4G10-4D5 light chain, LEU-PTR 著者 Mou, K, Leung, K, Wells, J.A. 登録日 2018-05-13 公開日 2018-11-28 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J. Am. Chem. Soc., 140, 2018
6DF2	Improved anti-phosphotyrosine antibody 4G10-S5-4D5 Fab complexed with phosphotyrosine peptide 分子名称: Anti-phosphotyrosine antibody c310-4D5 heavy chain, Anti-phosphotyrosine antibody c310-4D5 light chain, LEU-PTR-LEU 著者 Mou, K, Leung, K, Wells, J.A. 登録日 2018-05-13 公開日 2018-11-28 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif. J. Am. Chem. Soc., 140, 2018
6DF3	Crystal structure of ternary complex of IL-24 with soluble receptors IL-22RA and IL-20RB 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Lubkowski, J, Wlodawer, A. 登録日 2018-05-14 公開日 2018-08-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal Structure of the Labile Complex of IL-24 with the Extracellular Domains of IL-22R1 and IL-20R2. J. Immunol., 201, 2018
6DF4	TAF1-BD2 in complex with Cpd8 (6-(but-3-en-1-yl)-4-(3-(morpholine-4-carbonyl)phenyl)-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one) 分子名称: 6-(but-3-en-1-yl)-4-[3-(morpholine-4-carbonyl)phenyl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one, Transcription initiation factor TFIID subunit 著者 Murray, J.M, Tang, Y. 登録日 2018-05-14 公開日 2018-10-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like. J. Med. Chem., 61, 2018
6DF5	Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS) 分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ... 著者 Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E. 登録日 2018-05-14 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.819 Å) 主引用文献 A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences. Biochemistry, 2020
6DF6	Crystal structure of estrogen receptor alpha in complex with receptor degrader 16ab 分子名称: (8R)-8-(4-{2-[3-(fluoromethyl)azetidin-1-yl]ethoxy}phenyl)-1,8-dihydro-2H-[1]benzopyrano[4,3-d][1]benzoxepine-5,11-diol, Estrogen receptor, GLYCEROL 著者 Kiefer, J.R, Vinogradova, M, Liang, J, Zhang, B, Ortwine, D.F, Nettles, K.W, Nwachukwu, J.C. 登録日 2018-05-14 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. Bioorg. Med. Chem. Lett., 29, 2019

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