PDB: 36939 件ウェブページステータス検索Chemie searchBIRD

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4BV5	Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV. 分子名称: 4-(aminomethyl)-N-(benzenesulfonyl)cyclohexanecarboxamide, APOLIPOPROTEIN(A) 著者 Sandmark, J, Althage, M, Andersson, G.M.K, Antonsson, T, Blaho, S, Bodin, C, Bostrom, J, Chen, Y, Dahlen, A, Eriksson, P.O, Evertsson, E, Fex, T, Fjellstrom, O, Gustafsson, D, Hallberg, C, Hicks, R, Jarkvist, E, Johansson, C, Kalies, I, Kang, D, Svalstedt Karlsson, B, Kartberg, F, Legnehed, A, Lindqvist, A.M, Martinsson, S.A, Moberg, A, Petersson, A.U, Ridderstrom, M, Thelin, A, Tigerstrom, A, Vinblad, J, Xu, B, Knecht, W. 登録日 2013-06-25 公開日 2014-07-09 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A) To be Published
3OO3	Crystal Structure of the Orf6* (CYP165D3) Monooxygenase Involved in Teicoplanin Biosynthesis 分子名称: Oxy protein, PROTOPORPHYRIN IX CONTAINING FE 著者 Li, Z, Nair, S.K. 登録日 2010-08-30 公開日 2011-01-05 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesis. Proteins, 79, 2011
4C3U	Extensive counter-ion interactions with subtilisin in aqueous medium, Cs derivative 分子名称: CALCIUM ION, CESIUM ION, CHLORIDE ION, ... 著者 Cianci, M, Negroni, J, Helliwell, J.R, Halling, P.J. 登録日 2013-08-27 公開日 2014-08-20 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Extensive Counter-Ion Interactions Seen at the Surface of Subtilisin in an Aqueous Medium Rsc Adv, 2014
3OR0	Semi-synthetic ribonuclease S: cyanylated homocysteine at position 13 分子名称: Ribonuclease pancreatic 著者 Fafarman, A.T, Boxer, S.G. 登録日 2010-09-05 公開日 2010-10-20 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Nitrile bonds as infrared probes of electrostatics in ribonuclease S. J.Phys.Chem.B, 114, 2010
7FHT	Crystal structure of DYRK1A in complex with RD0448 分子名称: (5~{Z})-5-[(3-ethynyl-4-methoxy-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A 著者 Kikuchi, M, Sumida, Y, Hosoya, T, Kii, I, Umehara, T. 登録日 2021-07-30 公開日 2022-03-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. Eur.J.Med.Chem., 227, 2022
3OJ1	Structure of the H55D mutant of dehaloperoxidase-hemoglobin A from Amphitrite ornata 分子名称: Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION 著者 Zhao, J, De Serrano, V.S, Franzen, S. 登録日 2010-08-20 公開日 2011-08-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Effect of the H55D mutation on the kinetics and structure of dehaloperoxidase-hemoglobin A To be Published
3OJP	D52N Mutant of Hen Egg White Lysozyme (HEWL) 分子名称: ACETATE ION, CHLORIDE ION, Lysozyme C, ... 著者 O'Meara, F, Bradley, J, O'Rourke, P.E, Webb, H, Tynan-Connolly, B.M, Nielsen, J.E. 登録日 2010-08-23 公開日 2011-03-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 D52N Mutant of Hen Egg White Lysozyme (HEWL) TO BE PUBLISHED
6FBL	NMR Solution Structure of MINA-1(254-334) 分子名称: MINA-1 著者 Michel, E, Allain, F. 登録日 2017-12-19 公開日 2019-01-30 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans. Cell Death Differ., 26, 2019
7FHS	Crystal structure of DYRK1A in complex with RD0392 分子名称: (5~{Z})-5-[(3-ethoxy-4-oxidanyl-phenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, GLYCEROL 著者 Kikuchi, M, Sumida, T, Hosoya, T, Kii, I, Umehara, T. 登録日 2021-07-30 公開日 2022-03-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Structure-activity relationship for the folding intermediate-selective inhibition of DYRK1A. Eur.J.Med.Chem., 227, 2022
3OV1	Crystal Structure of the Grb2 SH2 Domain in Complex with a pYXN-Derived Tripeptide 分子名称: FORMIC ACID, GLYCEROL, Growth factor receptor-bound protein 2, ... 著者 Clements, J.H, Martin, S.F. 登録日 2010-09-15 公開日 2011-11-02 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Protein-ligand interactions: thermodynamic effects associated with increasing nonpolar surface area. J.Am.Chem.Soc., 133, 2011
6EST	INTERACTION OF THE PEPTIDE CF3-LEU-ALA-NH-C6H4-CF3(TFLA) WITH PORCINE PANCREATIC ELASTASE. X-RAY STUDIES AT 1.8 ANGSTROMS 分子名称: CALCIUM ION, DIMETHYLFORMAMIDE, PORCINE PANCREATIC ELASTASE, ... 著者 Prange, T, Li De Lasierra, I. 登録日 1990-06-15 公開日 1991-10-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Interaction of the peptide CF3-Leu-Ala-NH-C6H4-CF3 (TFLA) with porcine pancreatic elastase. X-ray studies at 1.8 A. J.Mol.Recog., 3, 1990
7FCW	X-ray structure of H2O-solvent lysozyme 分子名称: CHLORIDE ION, Lysozyme C, NICKEL (II) ION 著者 Chatake, T, Tanaka, I, Kusaka, K, Fujiwara, S. 登録日 2021-07-15 公開日 2022-04-06 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Protonation states of hen egg-white lysozyme observed using D/H contrast neutron crystallography. Acta Crystallogr D Struct Biol, 78, 2022
7FCU	X-ray structure of D2O-solvent lysozyme 分子名称: CHLORIDE ION, Lysozyme C, NICKEL (II) ION 著者 Chatake, T, Tanaka, I, Kusaka, K, Fujiwara, S. 登録日 2021-07-15 公開日 2022-04-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Protonation states of hen egg-white lysozyme observed using D/H contrast neutron crystallography. Acta Crystallogr D Struct Biol, 78, 2022
3OO4	R-state human hemoglobin: nitriheme modified at alpha 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, NITRITE ION, ... 著者 Yi, J, Thormas, L.M, Richter-Addo, G.B. 登録日 2010-08-30 公開日 2011-09-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic Trapping of Heme Loss Intermediates during the Nitrite-Induced Degradation of Human Hemoglobin. Biochemistry, 50, 2011
6FOI	Human Cys57/156Ala superoxide dismutase-1 (SOD1), as isolated. 分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION 著者 Wright, G.S.A, Sala, F.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S. 登録日 2018-02-07 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS. Plos Biol., 17, 2019
3OO1	Structure of E. Coli CheY mutant A113P in the absence of Sulfate 分子名称: Chemotaxis protein CheY, MAGNESIUM ION 著者 Immormino, R.M, Bourret, R.B. 登録日 2010-08-30 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Exploring the effect of an allosteric site on conformational coupling in CheY To be Published
3OIA	Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C8GluEtg-Bio 分子名称: Camphor 5-monooxygenase, N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-N'-(8-{[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-ylcarbonyl]amino}octyl)pentanediamide, POTASSIUM ION, ... 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-08-18 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-C8GluEtg-Bio To be Published
7EOD	MITF HLHLZ Delta AKE 分子名称: GLYCEROL, Isoform M1 of Microphthalmia-associated transcription factor 著者 Li, P, Liu, Z, Fang, P, Wang, J. 登録日 2021-04-22 公開日 2022-04-27 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
4C9P	Structure of camphor bound T260A mutant of CYP101D1 分子名称: CAMPHOR, CYTOCHROME P450, GLYCEROL, ... 著者 Batabyal, D, L Poulos, T. 登録日 2013-10-02 公開日 2013-12-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1. Biochemistry, 52, 2013
4CAA	CLEAVED ANTICHYMOTRYPSIN T345R 分子名称: ANTICHYMOTRYPSIN 著者 Lukacs, C.M, Christianson, D.W. 登録日 1997-08-14 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
3OL5	Crystal Structure of Cytochrome P450cam crystallized with a tethered substrate analog 3OH-AdaC1-C8-Dans 分子名称: (1R,3S,5R,7S)-N-[8-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)octyl]-3-hydroxytricyclo[3.3.1.1~3,7~]decane-1-carboxamide, Camphor 5-monooxygenase, POTASSIUM ION, ... 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-08-25 公開日 2010-11-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized with a tethered substrate analog 3OH-AdaC1-C8-Dans To be Published
4C7Q	Solution structure of the Nt. GR-RBP1 RRM domain 分子名称: RNA-BINDING GLYCINE-RICH PROTEIN 著者 Kahn, F, Boelens, R, Saqlan, S.M.S, van Ingen, H. 登録日 2013-09-24 公開日 2013-10-02 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structural Basis of Nucleic Acid Binding by Nicotiana Tabacum Glycine-Rich RNA Binding Protein: Implications for its RNA Chaperone Function Nucleic Acids Res., 42, 2014
3OTF	Structural basis for the cAMP-dependent gating in human HCN4 channel 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 著者 Xu, X, Vysotskaya, Z.V, Liu, Q, Zhou, L. 登録日 2010-09-11 公開日 2010-10-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for the cAMP-dependent gating in the human HCN4 channel. J.Biol.Chem., 285, 2010
6FQF	THE X-RAY STRUCTURE OF FERRIC-BETA4 HUMAN HEMOGLOBIN 分子名称: Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE 著者 Mazzarella, L, Merlino, A, Balasco, N, Balsamo, A, Vergara, A. 登録日 2018-02-14 公開日 2018-06-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the ferric homotetrameric beta4human hemoglobin. Biophys. Chem., 240, 2018
3OTS	MDR769 HIV-1 protease complexed with MA/CA hepta-peptide 分子名称: MA/CA substrate peptide, Multi-drug resistant HIV-1 protease 著者 Liu, Z, Wang, Y, Brunzelle, J, Kovari, I.A, Kovari, L.C. 登録日 2010-09-13 公開日 2011-03-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Nine Crystal Structures Determine the Substrate Envelope of the MDR HIV-1 Protease. Protein J., 30, 2011

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