PDB: 97814 件ウェブページステータス検索Chemie searchBIRD

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6VHW	Klebsiella oxytoca NpsA N-terminal subdomain in complex with 3-hydroxybenzoyl-AMSN 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-deoxy-5'-{[(3-hydroxybenzene-1-carbonyl)sulfamoyl]amino}adenosine, BROMIDE ION, ... 著者 Kreitler, D.F, Gulick, A.M. 登録日 2020-01-10 公開日 2020-06-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Biosynthesis, Mechanism of Action, and Inhibition of the Enterotoxin Tilimycin Produced by the Opportunistic PathogenKlebsiella oxytoca. Acs Infect Dis., 6, 2020
2BNK	The structure of phage phi29 replication organizer protein p16.7 分子名称: EARLY PROTEIN GP16.7 著者 Albert, A, Asensio, J.L, Munoz-Espin, D, Gonzalez, C, Hermoso, J.A, Villar, L, Jimenez-Barbero, J, Salas, M, Meijer, W.J.J. 登録日 2005-03-28 公開日 2005-04-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of the Functional Domain of {Varphi}29 Replication Organizer: Insights Into Oligomerization and DNA Binding. J.Biol.Chem., 280, 2005
8GBK	Dri1 hemoprotein variant H79A-R90A with a zinc-mirror heme site 分子名称: HEME B/C, Ssr1698 protein 著者 Yee, E.F, Blaby-Haas, C. 登録日 2023-02-26 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria. Nat Commun, 15, 2024
4OKQ	Crystal structure of the single-stranded RNA binding protein HutP from Geobacillus thermodenitrificans 分子名称: HISTIDINE, Hut operon positive regulatory protein, MAGNESIUM ION 著者 Thiruselvam, V, Ponnuswamy, M.N, Kumarevel, T.S. 登録日 2014-01-22 公開日 2014-03-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the single-stranded RNA binding protein HutP from Geobacillus thermodenitrificans Biochem.Biophys.Res.Commun., 446, 2014
6V3C	K2P2.1(TREK-1)I110D:Ru360 bound channel structure 分子名称: CADMIUM ION, HEXANE, N-OCTANE, ... 著者 Pope, L, Lolicato, M, Minor, D.L. 登録日 2019-11-25 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.51 Å) 主引用文献 Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism. Cell Chem Biol, 2020
8QFD	UFL1 E3 ligase bound 60S ribosome 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Makhlouf, L, Kulathu, Y, Zeqiraj, E. 登録日 2023-09-04 公開日 2024-02-21 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
3JQD	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-4-oxo-6-phenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (DX7) 分子名称: 2-amino-4-oxo-6-phenyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, ACETATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Tulloch, L.B, Hunter, W.N. 登録日 2009-09-06 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
6V7T	Crystal structure of CTX-M-14 E166A/D240G beta-lactamase in complex with ceftazidime 分子名称: ACYLATED CEFTAZIDIME, Beta-lactamase 著者 Brown, C.A, Hu, L, Sankaran, B, Prasad, B.V.V, Palzkill, T.G. 登録日 2019-12-09 公開日 2020-04-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Antagonism between substitutions in beta-lactamase explains a path not taken in the evolution of bacterial drug resistance. J.Biol.Chem., 295, 2020
6VAG	Crystal structure of the oligomerization domain of phosphoprotein from parainfluenza virus 5 分子名称: GLYCEROL, Phosphoprotein 著者 Aggarwal, M, Abdella, R, He, Y, Lamb, R.A. 登録日 2019-12-17 公開日 2020-02-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure of a paramyxovirus polymerase complex reveals a unique methyltransferase-CTD conformation. Proc.Natl.Acad.Sci.USA, 117, 2020
3JQ7	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 6-phenylpteridine-2,4,7-triamine (DX2) 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 6-phenylpteridine-2,4,7-triamine, ACETATE ION, ... 著者 Tulloch, L.B, Hunter, W.N. 登録日 2009-09-06 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
3JQF	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 1,3,5-triazine-2,4,6-triamine (AX2) 分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, 1,3,5-triazine-2,4,6-triamine, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... 著者 Tulloch, L.B, Hunter, W.N. 登録日 2009-09-06 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
6FD0	Human KIBRA C2 domain mutant M734I S735A 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Protein KIBRA 著者 Crennell, S.J, Posner, M.G, Bagby, S. 登録日 2017-12-21 公開日 2018-05-16 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.64215851 Å) 主引用文献 Distinctive phosphoinositide- and Ca2+-binding properties of normal and cognitive performance-linked variant forms of KIBRA C2 domain. J. Biol. Chem., 293, 2018
5IZM	The crystal structure of human eEFSec in complex with GDPNP 分子名称: MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Selenocysteine-specific elongation factor 著者 Dobosz-Bartoszek, M, Otwinowski, Z, Simonovic, M. 登録日 2016-03-25 公開日 2016-10-12 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Crystal structures of the human elongation factor eEFSec suggest a non-canonical mechanism for selenocysteine incorporation. Nat Commun, 7, 2016
6WT5	Structure of a bacterial STING receptor from Capnocytophaga granulosa 分子名称: Bacterial STING 著者 Morehouse, B.R, Govande, A.A, Millman, A, Keszei, A.F.A, Lowey, B, Ofir, G, Shao, S, Sorek, R, Kranzusch, P.J. 登録日 2020-05-01 公開日 2020-09-09 最終更新日 2020-10-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 STING cyclic dinucleotide sensing originated in bacteria. Nature, 586, 2020
6MFR	Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3) 分子名称: PHENOL, PHOSPHATE ION, Protein argonaute-2, ... 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-09-12 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6MFN	Human Argonaute2-miR-27a bound to HSUR1 target RNA 分子名称: PHENOL, Protein argonaute-2, RNA (5'-R(P*UP*CP*UP*GP*UP*GP*AP*UP*AP*A)-3'), ... 著者 Sheu-Gruttadauria, J, MacRae, I.J. 登録日 2018-09-11 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6VYA	Crystal structure of NotF in complex with brevianamide F and DMSPP 分子名称: (3S,8aS)-3-(1H-indol-3-ylmethyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dione, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Deoxybrevianamide E synthase notF 著者 Dan, Q, Smith, J.L. 登録日 2020-02-25 公開日 2021-02-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (-)-Eurotiumin A. J.Am.Chem.Soc., 144, 2022
5UP9	Crystal Structure of Zn-bound Human Heavy-Chain ferritin variant 122H-delta C-star with para-xylenedihydroxamate 分子名称: 2,2'-(1,4-phenylene)bis(N-hydroxyacetamide), DI(HYDROXYETHYL)ETHER, Ferritin heavy chain, ... 著者 Bailey, J.B, Zhang, L, Chiong, J.A, Ahn, S, Tezcan, F.A. 登録日 2017-02-01 公開日 2017-09-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Synthetic Modularity of Protein-Metal-Organic Frameworks. J. Am. Chem. Soc., 139, 2017
5J4D	E. coli release factor 1 bound to the 70S ribosome in response to a pseudouridylated stop codon 分子名称: 16S ribosomal RNA, 25S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2016-03-31 公開日 2016-05-18 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural Basis for Translation Termination on a Pseudouridylated Stop Codon. J.Mol.Biol., 428, 2016
8RTY	Structure of the F-actin barbed end bound by Cdc12 and profilin (ring complex) at a resolution of 6.3 Angstrom 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... 著者 Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. 登録日 2024-01-29 公開日 2024-04-10 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (6.25 Å) 主引用文献 Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
3JQA	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-1,9-dihydro-6H-purine-6-thione (DX4) 分子名称: 2-amino-1,9-dihydro-6H-purine-6-thione, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pteridine reductase 1 著者 Tulloch, L.B, Hunter, W.N. 登録日 2009-09-06 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
6BM0	Cryo-EM structure of human CPSF-160-WDR33 complex at 3.8 A resolution 分子名称: Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33 著者 Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L. 登録日 2017-11-12 公開日 2017-11-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6W3N	APE1 exonuclease substrate complex D148E 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(C7R))-3'), ... 著者 Freudenthal, B.D, Whitaker, A.M. 登録日 2020-03-09 公開日 2020-06-10 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Molecular and structural characterization of disease-associated APE1 polymorphisms. DNA Repair (Amst.), 91-92, 2020
3JQC	Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (JU2) 分子名称: 2-amino-6-bromo-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Pteridine reductase 1 著者 Tulloch, L.B, Hunter, W.N. 登録日 2009-09-06 公開日 2009-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-based design of pteridine reductase inhibitors targeting african sleeping sickness and the leishmaniases. J.Med.Chem., 53, 2010
5IT9	Structure of the yeast Kluyveromyces lactis small ribosomal subunit in complex with the cricket paralysis virus IRES. 分子名称: 18S ribosomal RNA, Cricket paralysis virus IRES RNA, MAGNESIUM ION, ... 著者 Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S. 登録日 2016-03-16 公開日 2016-05-18 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural characterization of ribosome recruitment and translocation by type IV IRES. Elife, 5, 2016

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