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6LUO
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BU of 6luo by Molmil
Structure of nurse shark beta-2-microglobulin
分子名称: Beta-2-microglobulin
著者Xia, C, Wu, Y.
登録日2020-01-30
公開日2021-04-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献The Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between beta 2 -Microglobulin and H Chain Conserved in Evolution.
J Immunol., 2021
6LUP
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BU of 6lup by Molmil
Crystal structure of shark MHC CLASS I for 2.3 angstrom
分子名称: Beta-2-microglobulin, MHC class I protein, PHE-ALA-ASN-PHE-PHE-ILE-ARG-GLY-LEU
著者Wu, Y, Xia, C.
登録日2020-01-30
公開日2021-04-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.302 Å)
主引用文献The Structure of a Peptide-Loaded Shark MHC Class I Molecule Reveals Features of the Binding between beta 2 -Microglobulin and H Chain Conserved in Evolution.
J Immunol., 2021
4Z78
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BU of 4z78 by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2015-04-06
公開日2015-06-24
最終更新日2015-08-12
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
4KVC
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BU of 4kvc by Molmil
2H2 Fab fragment of immature Dengue virus
分子名称: Ig heavy chain V region MOPC 21, Igh protein, Ig kappa chain V-V region MOPC 21, ...
著者Wang, Z, Rossmann, M.G.
登録日2013-05-22
公開日2013-07-24
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (2.306 Å)
主引用文献Obstruction of Dengue Virus Maturation by Fab Fragments of the 2H2 Antibody.
J.Virol., 87, 2013
4WWI
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BU of 4wwi by Molmil
Crystal structure of the C domain of staphylococcal protein A in complex with the Fc fragment of human IgG at 2.3 Angstrom resolution
分子名称: Ig gamma-3 chain C region, Immunoglobulin G-binding protein A
著者Deis, L.N, Oas, T.G.
登録日2014-11-11
公開日2015-07-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.307 Å)
主引用文献Suppression of conformational heterogeneity at a protein-protein interface.
Proc.Natl.Acad.Sci.USA, 112, 2015
6BGA
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BU of 6bga by Molmil
2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 peptide,MHC I-Ek B chain, ...
著者Gee, M.H, Sibener, L.V, Birnbaum, M.E, Jude, K.M, Garcia, K.C.
登録日2017-10-27
公開日2018-07-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.307 Å)
主引用文献Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8ED1
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BU of 8ed1 by Molmil
Bovine Fab 5C1
分子名称: 5C1 Fab heavy chain, 5C1 Fab light chain, GLYCEROL, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2022-09-02
公開日2023-09-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc.Natl.Acad.Sci.USA, 120, 2023
6A6H
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BU of 6a6h by Molmil
Crystal Structure of Swine Major Histocompatibility Complex Class I SLA-2*040202 For 2.3 Angstrom
分子名称: Beta-2-microglobulin, MET-THR-ALA-HIS-ILE-VAL-VAL-PRO-TYR, MHC class I antigen
著者Ning, S, Wang, Z.B.
登録日2018-06-28
公開日2019-07-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Crystallization of SLA-2*04:02:02 complexed with a CTL epitope derived from FMDV.
Res. Vet. Sci., 128, 2019
8D5F
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BU of 8d5f by Molmil
The complex of Gtf2b neoantigen TGAARFDEF Presented by H2-Dd
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Custodio, J.M.F, Baker, B.M.
登録日2022-06-04
公開日2022-07-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural and physical features that distinguish tumor-controlling from inactive cancer neoepitopes.
Proc.Natl.Acad.Sci.USA, 120, 2023
6P6D
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BU of 6p6d by Molmil
HUMAN IGG1 FC FRAGMENT, C239 INSERTION MUTANT
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CYSTEINE, IgG1 Fc fragment
著者Gallagher, D.T, Dimasi, N, McCullough, C.
登録日2019-06-03
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structure and Dynamics of a Site-Specific Labeled Fc Fragment with Altered Effector Functions.
Pharmaceutics, 11, 2019
3V5K
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BU of 3v5k by Molmil
HLA2.1 KVAELVWFL
分子名称: Beta-2-microglobulin, GLYCEROL, HIV-based altered-peptide ligand KVAELVWFL, ...
著者Collins, E.J, Lee, H.Y.
登録日2011-12-16
公開日2012-12-19
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Prediction of Immunogenicity of altered-peptide ligands to HIV bound to MHC
To be Published
4PV8
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BU of 4pv8 by Molmil
Crystal Structure of H2Kb-Q600F complex
分子名称: ACETATE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Twist, K.-A, Rossjohn, J, Gras, S.
登録日2014-03-15
公開日2014-04-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes.
J.Immunol., 192, 2014
4WDI
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BU of 4wdi by Molmil
Weak TCR binding to an unstable insulin epitope drives type 1 diabetes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Rizkallah, P.J, Cole, D.K.
登録日2014-09-08
公開日2015-06-24
最終更新日2015-07-01
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Distortion of the Major Histocompatibility Complex Class I Binding Groove to Accommodate an Insulin-derived 10-Mer Peptide.
J.Biol.Chem., 290, 2015
6J2D
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BU of 6j2d by Molmil
Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1
分子名称: HeV1, Ptal-N*01:01, beta-2 microglobulin
著者Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
登録日2019-01-01
公開日2019-09-18
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.313 Å)
主引用文献Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6IEX
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BU of 6iex by Molmil
Crystal structure of HLA-B*4001 in complex with SARS-CoV derived peptide N216-225 GETALALLLL
分子名称: Beta-2-microglobulin, GLY-GLU-THR-ALA-LEU-ALA-LEU-LEU-LEU-LEU, MHC class I antigen
著者Ji, W, Niu, L, Peng, W, Zhang, Y, Shi, Y, Qi, J, Gao, G.F, Liu, W.J.
登録日2018-09-17
公開日2019-09-18
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (2.314 Å)
主引用文献Salt bridge-forming residues positioned over viral peptides presented by MHC class I impacts T-cell recognition in a binding-dependent manner.
Mol.Immunol., 112, 2019
5VGD
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BU of 5vgd by Molmil
Crystal Structure of HLA-C*0501 in complex with SAE
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, Cw-5 alpha chain, ...
著者Gras, S, Rossjohn, J.
登録日2017-04-11
公開日2017-05-31
最終更新日2017-07-12
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural and regulatory diversity shape HLA-C protein expression levels.
Nat Commun, 8, 2017
5VZY
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BU of 5vzy by Molmil
Crystal structure of crenezumab Fab in complex with Abeta
分子名称: Amyloid beta A4 protein, Crenezumab Fab heavy chain,Immunoglobulin gamma-1 heavy chain, Crenezumab Fab light chain,Immunoblobulin light chain
著者Ultsch, M, Wang, W.
登録日2017-05-29
公開日2017-08-09
最終更新日2017-09-13
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structure of Crenezumab Complex with Abeta Shows Loss of beta-Hairpin.
Sci Rep, 6, 2016
5V43
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BU of 5v43 by Molmil
Engineered human IgG Fc domain aglyco801
分子名称: Ig gamma-1 chain C region
著者Yan, W, Marshall, N, Zhang, Y.J.
登録日2017-03-08
公開日2017-06-21
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
6BLX
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BU of 6blx by Molmil
Crystal structure of IAg7 in complex with insulin mimotope p8G9E
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, Y, Dai, S.
登録日2017-11-11
公開日2017-12-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.323 Å)
主引用文献C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MU3
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BU of 6mu3 by Molmil
Anti-HIV-1 Fab 2G12 + Man7 re-refinement
分子名称: Fab 2G12, heavy chain, light chain, ...
著者Wilson, I.A, Calarese, D.A, Stanfield, R.L.
登録日2018-10-22
公開日2018-10-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.327 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
8QFY
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BU of 8qfy by Molmil
Crystal structure of high affinity TCR in complex with pHLA harbouring bacterial peptide
分子名称: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Pengelly, R.J, Robinson, R.A.
登録日2023-09-05
公開日2024-05-15
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.
Proc.Natl.Acad.Sci.USA, 121, 2024
8SOS
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BU of 8sos by Molmil
Human CD1d presenting sphingomyelin C24:1 in complex with VHH nanobody 1D17
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, ...
著者Shahine, A, Rossjohn, J.
登録日2023-04-29
公開日2023-12-13
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions.
J Immunother Cancer, 11, 2023
5C08
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BU of 5c08 by Molmil
1E6 TCR in Complex with HLA-A0e carrying RQWGPDPAAV
分子名称: 1,2-ETHANEDIOL, 1E6 TCR Alpha Chain, 1E6 TCR Beta Chain, ...
著者Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K.
登録日2015-06-12
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.332 Å)
主引用文献Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
J.Clin.Invest., 126, 2016
6VIU
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BU of 6viu by Molmil
HLA-B*15:02 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2020-01-14
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.334 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published
6VB4
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BU of 6vb4 by Molmil
HLA-B*15:02 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Andring, J, McKenna, R, Ostrov, D.A.
登録日2019-12-18
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.334 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published

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件を2024-07-10に公開中

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