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3Q2Q
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Crystal structure of geranylgeranyl pyrophosphate synthase from Corynebacterium glutamicum complexed with calcium and isoprenyl diphosphate
分子名称: CALCIUM ION, DIMETHYLALLYL DIPHOSPHATE, GLYCEROL, ...
著者Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Poulter, C.D, Gerlt, J.A, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-12-20
公開日2011-01-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
3PDE
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BU of 3pde by Molmil
Crystal structure of geranylgeranyl pyrophosphate synthase from Lactobacillus brevis atcc 367 complexed with isoprenyl diphosphate and magnesium
分子名称: DIMETHYLALLYL DIPHOSPHATE, Farnesyl-diphosphate synthase, GLYCEROL, ...
著者Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Poulter, C.D, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-10-22
公開日2010-11-17
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
7TZH
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BU of 7tzh by Molmil
Structure of human LAG3 domains 3-4 in complex with antibody single chain-variable fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, scFvF7
著者Ming, Q, Tran, T.H, Luca, V.C.
登録日2022-02-15
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
7TZE
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Structure of murine LAG3 domains 1-2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein
著者Ming, Q, Tran, T.H, Luca, V.C.
登録日2022-02-15
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition.
Nat.Immunol., 23, 2022
5A0G
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BU of 5a0g by Molmil
N-terminal thioester domain of surface protein from Clostridium perfringens
分子名称: SURFACE ANCHORED PROTEIN
著者Walden, M, Edwards, J.M, Dziewulska, A.M, Kan, S.-Y, Schwarz-Linek, U, Banfield, M.J.
登録日2015-04-20
公開日2015-06-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献An internal thioester in a pathogen surface protein mediates covalent host binding.
Elife, 4, 2015
4FP4
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BU of 4fp4 by Molmil
Crystal structure of isoprenoid synthase a3mx09 (target efi-501993) from pyrobaculum calidifontis
分子名称: GERAN-8-YL GERAN, Polyprenyl synthetase, UNKNOWN ATOM OR ION, ...
著者Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-06-21
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F62
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BU of 4f62 by Molmil
Crystal structure of a putative farnesyl-diphosphate synthase from Marinomonas sp. MED121 (Target EFI-501980)
分子名称: CHLORIDE ION, GLYCEROL, Geranyltranstransferase, ...
著者Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-05-14
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
1F3W
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BU of 1f3w by Molmil
RECOMBINANT RABBIT MUSCLE PYRUVATE KINASE
分子名称: MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ...
著者Wooll, J.O, Friesen, R.H.E, White, M.A, Watowich, S.J, Fox, R.O, Lee, J.C, Czerwinski, E.W.
登録日2000-06-06
公開日2001-10-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase.
J.Mol.Biol., 312, 2001
1F3X
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S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE
分子名称: MANGANESE (II) ION, POTASSIUM ION, PYRUVATE KINASE, ...
著者Wooll, J.O, Friesen, R.H.E, White, M.A, Watowich, S.J, Fox, R.O, Lee, J.C, Czerwinski, E.W.
登録日2000-06-06
公開日2001-10-03
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase.
J.Mol.Biol., 312, 2001
6O4J
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BU of 6o4j by Molmil
Amyloid Beta KLVFFAENVGS 16-26 D23N Iowa mutation
分子名称: Amyloid-beta precursor protein
著者Griner, S.L, Sawaya, M.R, Rodriguez, J.A, Cascio, D, Gonen, T.
登録日2019-02-28
公開日2019-10-30
最終更新日2023-10-11
実験手法ELECTRON CRYSTALLOGRAPHY (1.402 Å)
主引用文献Structure based inhibitors of Amyloid Beta core suggest a common interface with Tau.
Elife, 8, 2019
3PKO
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BU of 3pko by Molmil
Crystal structure of geranylgeranyl pyrophosphate synthase from lactobacillus brevis atcc 367 complexed with citrate
分子名称: CITRIC ACID, GLYCEROL, Geranylgeranyl pyrophosphate synthase
著者Patskovsky, Y, Toro, R, Rutter, M, Chang, S, Sauder, J.M, Poulter, C.D, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2010-11-11
公開日2010-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
4AWN
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BU of 4awn by Molmil
Structure of recombinant human DNase I (rhDNaseI) in complex with Magnesium and Phosphate.
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Parsiegla, G, Noguere, C, Santell, L, Lazarus, R.A, Bourne, Y.
登録日2012-06-04
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The Structure of Human DNase I Bound to Magnesium and Phosphate Ions Points to a Catalytic Mechanism Common to Members of the DNase I-Like Superfamily.
Biochemistry, 51, 2012
3QQV
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BU of 3qqv by Molmil
Crystal structure of geranylgeranyl pyrophosphate synthase from corynebacterium glutamicum complexed with isoprenyl diphosphate and magnesium
分子名称: DIMETHYLALLYL DIPHOSPHATE, GLYCEROL, Geranylgeranyl pyrophosphate synthase, ...
著者Patskovsky, Y, Toro, R, Sauder, J.M, Poulter, C.D, Gerlt, J.A, Burley, S.K, Almo, S.C, Enzyme Function Initiative (EFI), New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2011-02-16
公開日2011-03-02
最終更新日2021-02-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
2OFJ
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BU of 2ofj by Molmil
Crystal structure of the E190A mutant of o-succinylbenzoate synthase from Escherichia coli
分子名称: O-succinylbenzoate synthase
著者Nagatani, R.A, Gonzalez, A, Shoichet, B.K, Brinen, L.S, Babbitt, P.C.
登録日2007-01-03
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Stability for Function Trade-Offs in the Enolase Superfamily "Catalytic Module".
Biochemistry, 46, 2007
5H9B
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BU of 5h9b by Molmil
Drosophila CaMKII-wt in complex with a fragment of the Eag potassium channel and Mg2+/AMPPN
分子名称: AMP PHOSPHORAMIDATE, Calcium/calmodulin-dependent protein kinase II, isoform C, ...
著者Castro-Rodrigues, A.F, Morais-Cabral, J.H.
登録日2015-12-27
公開日2017-01-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献The Interaction between the Drosophila EAG Potassium Channel and the Protein Kinase CaMKII Involves an Extensive Interface at the Active Site of the Kinase.
J.Mol.Biol., 430, 2018
3ZQR
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BU of 3zqr by Molmil
NMePheB25 insulin analogue crystal structure
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A.
登録日2011-06-10
公開日2011-08-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface.
J.Biol.Chem., 286, 2011
1TZ3
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BU of 1tz3 by Molmil
crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside
分子名称: 5-AMINOIMIDAZOLE RIBONUCLEOSIDE, POTASSIUM ION, putative sugar kinase
著者Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E.
登録日2004-07-09
公開日2004-10-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily
STRUCTURE, 12, 2004
3ZTC
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BU of 3ztc by Molmil
pVHL54-213-EloB-EloC complex _ (2S,4R)-N-((1,1'-biphenyl)-4-ylmethyl)- 4-hydroxy-1-(2-(3-methylisoxazol-5-yl)acetyl)pyrrolidine-2- carboxamide
分子名称: (4R)-N-(BIPHENYL-4-YLMETHYL)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-L-PROLINAMIDE, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, ...
著者Van Molle, I, Buckley, D.L, Crews, C.M, Ciulli, A.
登録日2011-07-06
公開日2012-07-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface.
Chem.Biol., 19, 2012
3QHC
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BU of 3qhc by Molmil
Crystal structure of Symerythrin from Cyanophora paradoxa, reduced with dithionite
分子名称: FE (III) ION, Symerythrin
著者Cooley, R.B, Arp, D.J, Karplus, P.A.
登録日2011-01-25
公開日2011-08-31
最終更新日2011-10-12
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Symerythrin structures at atomic resolution and the origins of rubrerythrins and the ferritin-like superfamily.
J.Mol.Biol., 413, 2011
3ZS2
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BU of 3zs2 by Molmil
TyrB25,NMePheB26,LysB28,ProB29-insulin analogue crystal structure
分子名称: CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN, ...
著者Antolikova, E, Zakova, L, Turkenburg, J.P, Watson, C.J, Hanclova, I, Sanda, M, Cooper, A, Kraus, T, Brzozowski, A.M, Jiracek, J.A.
登録日2011-06-21
公開日2011-08-31
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Non-Equivalent Role of Inter- and Intramolecular Hydrogen Bonds in the Insulin Dimer Interface.
J.Biol.Chem., 286, 2011
1TZ6
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BU of 1tz6 by Molmil
Crystal structure of aminoimidazole riboside kinase from Salmonella enterica complexed with aminoimidazole riboside and ATP analog
分子名称: 5-AMINOIMIDAZOLE RIBONUCLEOSIDE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E.
登録日2004-07-09
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily
STRUCTURE, 12, 2004
2YB1
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BU of 2yb1 by Molmil
Structure of an amidohydrolase from Chromobacterium violaceum (EFI target EFI-500202) with bound Mn, AMP and phosphate.
分子名称: ADENOSINE MONOPHOSPHATE, AMIDOHYDROLASE, MANGANESE (II) ION, ...
著者Vetting, M.W, Hillerich, B, Foti, R, Seidel, R.D, Zencheck, W.D, Toro, R, Imker, H.J, Raushel, F.M, Gerlt, J.A, Almo, S.C.
登録日2011-02-25
公開日2011-03-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献Prospecting for Unannotated Enzymes: Discovery of a 3',5'-Nucleotide Bisphosphate Phosphatase within the Amidohydrolase Superfamily.
Biochemistry, 53, 2014
1TYY
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BU of 1tyy by Molmil
Crystal structure of aminoimidazole riboside kinase from Salmonella enterica
分子名称: POTASSIUM ION, putative sugar kinase
著者Zhang, Y, Dougherty, M, Downs, D.M, Ealick, S.E.
登録日2004-07-08
公開日2004-10-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal Structure of an Aminoimidazole Riboside Kinase from Salmonella enterica; Implications for the Evolution of the Ribokinase Superfamily
STRUCTURE, 12, 2004
1OIH
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Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase
分子名称: PUTATIVE ALKYLSULFATASE ATSK, SODIUM ION
著者Mueller, I, Kahnert, A, Pape, T, Dierks, T, Meyer-Klauke, W, Kertesz, M, Uson, I.
登録日2003-06-18
公開日2004-03-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) -Ketoglutarate-Dependent Dioxygenase Superfamily
Biochemistry, 42, 2004
6BNP
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BU of 6bnp by Molmil
CryoEM structure of MyosinVI-actin complex in the rigor (nucleotide-free) state
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Gurel, P.S, Alushin, G.A.
登録日2017-11-17
公開日2018-01-10
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Cryo-EM structures reveal specialization at the myosin VI-actin interface and a mechanism of force sensitivity.
Elife, 6, 2017

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