8WUL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wul by Molmil](/molmil-images/mine/8wul) | Crystal structure of affinity enhanced TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen, ... | 著者 | Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. | 登録日 | 2023-10-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
|
|
8WTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wte by Molmil](/molmil-images/mine/8wte) | Crystal structure of TCR in complex with HLA-A*11:01 bound to KRAS-G12V peptide (VVGAVGVGK) | 分子名称: | Beta-2-microglobulin, KRAS-G12V nonamer peptide, MHC class I antigen (Fragment), ... | 著者 | Zhang, M.Y, Luo, L.J, Xu, W, Guan, F.H, Wang, X.Y, Zhu, P, Zhang, J.H, Zhou, X.Y, Wang, F, Ye, S. | 登録日 | 2023-10-18 | 公開日 | 2024-05-01 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Identification and affinity enhancement of T-cell receptor targeting a KRAS G12V cancer neoantigen. Commun Biol, 7, 2024
|
|
8VSP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vsp by Molmil](/molmil-images/mine/8vsp) | Cryo-EM structure of human invariant chain in complex with HLA-DQ | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, ... | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2024-01-24 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
8VRW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vrw by Molmil](/molmil-images/mine/8vrw) | Cryo-EM structure of human invariant chain in complex with HLA-DR15 | 分子名称: | HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Wang, N, Caveney, N.A, Jude, K.M, Garcia, K.C. | 登録日 | 2024-01-22 | 公開日 | 2024-05-08 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Structural insights into human MHC-II association with invariant chain. Proc.Natl.Acad.Sci.USA, 121, 2024
|
|
8WYI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wyi by Molmil](/molmil-images/mine/8wyi) | T cell receptor delta 2 gamma 9 with TCRD TM domain chimera of TRAC | 分子名称: | Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant,T cell receptor delta variable 2,T cell receptor delta constant,T cell receptor alpha chain constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1,T cell receptor gamma variable 9,T cell receptor gamma constant 1, T-cell surface glycoprotein CD3 delta chain, ... | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-31 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
|
|
8WXE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wxe by Molmil](/molmil-images/mine/8wxe) | Vgamma5Vdelta1 EH TCR-CD3 complex | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 1,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 5,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-28 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
|
|
8WY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8wy0 by Molmil](/molmil-images/mine/8wy0) | T cell receptor delta 2 gamma 9 with F283A, F290A, and F291A | 分子名称: | CHOLESTEROL, Signal peptide,flag tag,T cell receptor delta variable 2,T cell receptor delta constant, Signal peptide,flag tag,T cell receptor gamma variable 9,T cell receptor gamma constant 1, ... | 著者 | Xin, W, Huang, B, Chi, X, Liu, Y, Xu, M, Zhang, Y, Li, X, Su, Q, Zhou, Q. | 登録日 | 2023-10-30 | 公開日 | 2024-05-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of human gamma delta T cell receptor-CD3 complex. Nature, 630, 2024
|
|
6GB5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gb5 by Molmil](/molmil-images/mine/6gb5) | Structure of H-2Db with truncated SEV peptide and GL | 分子名称: | Beta-2-microglobulin, GLY-LEU, GLYCEROL, ... | 著者 | Hafstrand, I, Sandalova, T, Achour, A. | 登録日 | 2018-04-13 | 公開日 | 2019-03-06 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
7XQT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xqt by Molmil](/molmil-images/mine/7xqt) | The structure of FLA-K*00701/KP-FECV-11 | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | 登録日 | 2022-05-08 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
|
|
7XQS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xqs by Molmil](/molmil-images/mine/7xqs) | The structure of FLA-K*00701/KP-CoV-9 | 分子名称: | Beta-2-microglobulin, MHC class I antigen alpha chain, peptide from Spike glycoprotein | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | 登録日 | 2022-05-08 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
|
|
7XQU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7xqu by Molmil](/molmil-images/mine/7xqu) | The structure of FLA-E*00301/EM-FECV-10 | 分子名称: | Beta-2-microglobulin, MHC class I antigen, peptide from Nucleoprotein | 著者 | Qiao, P.W, Yue, C, Peng, W.Y, Liu, K.F, Huo, S.T, Zhang, D, Chai, Y, Qi, J.X, Sun, Z.Y, Gao, G.F, Liu, W.J, Wu, G.Z. | 登録日 | 2022-05-08 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Analysis of the characteristics of feline major histocompatibility complex class I molecules cross-presenting coronavirus peptides To Be Published
|
|
8DV1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dv1 by Molmil](/molmil-images/mine/8dv1) | SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to linker variant of affinity matured ACE2 mimetic CVD432 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion,Immunoglobulin gamma-1 heavy chain, Spike glycoprotein | 著者 | QCRG Structural Biology Consortium, Remesh, S.G, Merz, G.E, Brilot, A.F, Chio, U, Verba, K.A. | 登録日 | 2022-07-27 | 公開日 | 2022-08-31 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31, 2023
|
|
8DV2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dv2 by Molmil](/molmil-images/mine/8dv2) | SARS-CoV-2 Wuhan-hu-1-Spike-RBD bound to computationally engineered ACE2 mimetic CVD293 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2,Immunoglobulin gamma-1 heavy chain fusion, Spike glycoprotein | 著者 | QCRG Structural Biology Consortium, Remesh, S.G, Merz, G.E, Brilot, A.F, Chio, U, Verba, K.A. | 登録日 | 2022-07-27 | 公開日 | 2022-08-31 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Computational pipeline provides mechanistic understanding of Omicron variant of concern neutralizing engineered ACE2 receptor traps. Structure, 31, 2023
|
|
7Z50
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7z50 by Molmil](/molmil-images/mine/7z50) | |
6JOZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6joz by Molmil](/molmil-images/mine/6joz) | Crystal structure of BRLF peptide from EBV in complex with HLA-A1101. | 分子名称: | ALA-THR-ILE-GLY-THR-ALA-MET-TYR-LYS, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Huan, X, Xiao, Z, Tadwal, V.S, Ren, E.C. | 登録日 | 2019-03-25 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response. Sci Rep, 9, 2019
|
|
6E1I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e1i by Molmil](/molmil-images/mine/6e1i) | |
6E4X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6e4x by Molmil](/molmil-images/mine/6e4x) | |
8VDD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vdd by Molmil](/molmil-images/mine/8vdd) | Crystal structure of Proinsulin C-peptide bound to HLA-DQ8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, MHC class II HLA-DQ-alpha chain, ... | 著者 | Tran, T.M, Lim, J.J, Loh, T.Y, Mannering, I.S, Rossjohn, J, Reid, H.H. | 登録日 | 2023-12-14 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8. J.Biol.Chem., 2024
|
|
8VD2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vd2 by Molmil](/molmil-images/mine/8vd2) | Human TCR ET650-4 in complex with DQ8-InsC8-15-IAPP1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hybrid insulin peptide (HIP; InsC8-15-IAPP23-29 ), MHC class II HLA-DQ-alpha chain, ... | 著者 | Tran, T.M, Lim, J.J, Loh, T.Y, Mannering, I.S, Rossjohn, J, Reid, H.H. | 登録日 | 2023-12-14 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8. J.Biol.Chem., 2024
|
|
8VCX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vcx by Molmil](/molmil-images/mine/8vcx) | Human TCR A2.13 in complex with DQ8-InsCpep | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | 著者 | Tran, T.M, Lim, J.J, Loh, T.J, Mannering, I.S, Rossjohn, J, Reid, H.H. | 登録日 | 2023-12-14 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8. J.Biol.Chem., 2024
|
|
8VD0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vd0 by Molmil](/molmil-images/mine/8vd0) | Human TCR ET650-4 in complex with DQ8-InsC8-15-IAPP2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hybrid insulin peptide (HIP; InsC8-15-IAPP74-80),MHC class II HLA-DQ-beta-1 chimera, ... | 著者 | Tran, T.M, Lim, J.J, Loh, T.Y, Mannering, I.S, Rossjohn, J, Reid, H.H. | 登録日 | 2023-12-14 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8. J.Biol.Chem., 2024
|
|
8VCY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vcy by Molmil](/molmil-images/mine/8vcy) | Human TCR A2.13 in complex with DQ8-InsC8-15NPY | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Hybrid insulin peptide (HIP; InsC8-15-NPY68-74), ... | 著者 | Tran, T.M, Lim, J.J, Loh, T.Y, Mannering, I.S, Rossjohn, J, Reid, H.H. | 登録日 | 2023-12-14 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8. J.Biol.Chem., 2024
|
|
8VDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8vdu by Molmil](/molmil-images/mine/8vdu) | Crystal structure of hybrid insulin peptide (InsC8-15-IAPP74-80) bound to HLA-DQ8 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Hybrid insulin peptide (HIP; InsC8-15-IAPP74-80), ... | 著者 | Tran, T.M, Lim, J.J, Loh, T.Y, Mannering, I.S, Rossjohn, J, Reid, H.H. | 登録日 | 2023-12-17 | 公開日 | 2024-08-07 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | A structural basis of T cell cross-reactivity to native and spliced self-antigens presented by HLA-DQ8. J.Biol.Chem., 2024
|
|
6H6D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6h6d by Molmil](/molmil-images/mine/6h6d) | |
8E4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e4c by Molmil](/molmil-images/mine/8e4c) | IgM BCR fab truncated form | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain,Yellow fluorescent protein, B-cell antigen receptor complex-associated protein beta chain, ... | 著者 | Dong, Y, Pi, X, Wu, H, Reth, M. | 登録日 | 2022-08-18 | 公開日 | 2022-11-16 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural principles of B cell antigen receptor assembly. Nature, 612, 2022
|
|