PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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3MNR	Crystal Structure of Benzamide SNX-1321 bound to Hsp90 分子名称: 2-[(3,4,5-trimethoxyphenyl)amino]-4-(2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide, Heat shock protein HSP 90-alpha 著者 Veal, J.M, Fadden, P, Huang, K.H, Rice, J, Hall, S.E, Haytstead, T.A. 登録日 2010-04-22 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90. Chem.Biol., 17, 2010
3MH5	HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues 分子名称: DIISOPROPYL PHOSPHONATE, Protease do 著者 Krojer, T, Sawa, J, Huber, R, Clausen, T. 登録日 2010-04-07 公開日 2010-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat.Struct.Mol.Biol., 17, 2010
3MOJ	Structure of the RNA binding domain of the Bacillus subtilis YxiN protein complexed with a fragment of 23S ribosomal RNA 分子名称: ATP-dependent RNA helicase dbpA, RNA (69-MER) 著者 Hardin, J.W, Hu, Y, McKay, D.B. 登録日 2010-04-22 公開日 2010-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 Structure of the RNA binding domain of a DEAD-box helicase bound to its ribosomal RNA target reveals a novel mode of recognition by an RNA recognition motif. J.Mol.Biol., 402, 2010
6QPZ	Crystal structure of as isolated Y323E mutant of haem-Cu containing nitrite reductase from Ralstonia pickettii 分子名称: COPPER (II) ION, Copper-containing nitrite reductase, GLYCEROL, ... 著者 Antonyuk, S.V, Shenoy, R.T, Hedison, T.M, Eady, R.R, Hasnain, S.S, Scrutton, N.S. 登録日 2019-02-16 公開日 2019-11-06 最終更新日 2020-02-26 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Unexpected Roles of a Tether Harboring a Tyrosine Gatekeeper Residue in Modular Nitrite Reductase Catalysis. Acs Catalysis, 9, 2019
3MJ8	Crystal structure of HL4E10 Fab, a hamster Ab stimulatory for gammadelta T cells 分子名称: STIMULATORY HAMSTER ANTIBODY HL4E10 FAB HEAVY CHAIN, STIMULATORY HAMSTER ANTIBODY HL4E10 FAB LIGHT CHAIN 著者 Verdino, P, Wilson, I.A. 登録日 2010-04-12 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 cDNA sequence and Fab crystal structure of HL4E10, a hamster IgG lambda light chain antibody stimulatory for gammadelta T cells. Plos One, 6, 2011
3MQH	crystal structure of the 3-N-acetyl transferase WlbB from Bordetella petrii in complex with CoA and UDP-3-amino-2-acetamido-2,3-dideoxy glucuronic acid 分子名称: (2S,3S,4R,5R,6R)-5-(acetylamino)-4-amino-6-{[(R)-{[(R)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3-hydroxytetrahydro-2H-pyran-2-carboxylic acid, 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 thoden, J.B, holden, H.M. 登録日 2010-04-28 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Molecular structure of WlbB, a bacterial N-acetyltransferase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid . Biochemistry, 49, 2010
3MJS	Structure of A-type Ketoreductases from Modular Polyketide Synthase 分子名称: (2S)-2-hydroxybutanedioic acid, AmphB, D-MALATE, ... 著者 Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. 登録日 2010-04-13 公開日 2010-08-18 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase. Structure, 18, 2010
6QQC	Cryogenic temperature structure of Hen Egg White Lysozyme recorded after an accumulated dose of 110 kGy 分子名称: CHLORIDE ION, Lysozyme C 著者 Gotthard, G, Aumonier, S, Royant, A. 登録日 2019-02-18 公開日 2019-06-19 最終更新日 2019-07-31 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Specific radiation damage is a lesser concern at room temperature. Iucrj, 6, 2019
3MKD	Crystal structure of myosin-2 dictyostelium discoideum motor domain S456Y mutant in complex with adp-orthovanadate 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin-2 heavy chain, ... 著者 Kathmann, D, Diensthuber, R.P, Fedorov, R, Manstein, D.J, Tsiavaliaris, G. 登録日 2010-04-14 公開日 2011-04-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Switch-2 dependent modulation of the myosin power stroke To be Published
3MKW	Structure of sopB(155-272)-18mer complex, I23 form 分子名称: DNA (5'-D(*CP*TP*GP*GP*GP*AP*CP*CP*AP*TP*GP*GP*TP*CP*CP*CP*AP*G)-3'), Protein sopB, SULFATE ION 著者 Schumacher, M.A, Piro, K, Xu, W. 登録日 2010-04-15 公開日 2010-05-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Insight into F plasmid DNA segregation revealed by structures of SopB and SopB-DNA complexes. Nucleic Acids Res., 38, 2010
6DB4	JAK3 with Cyanamide CP34 分子名称: N-[(1S)-6-(5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl]imidoformamide, Tyrosine-protein kinase JAK3 著者 Vajdos, F.F. 登録日 2018-05-02 公開日 2018-11-28 最終更新日 2019-05-01 実験手法 X-RAY DIFFRACTION (1.662 Å) 主引用文献 Identification of Cyanamide-Based Janus Kinase 3 (JAK3) Covalent Inhibitors. J. Med. Chem., 61, 2018
6DC3	RSV prefusion F bound to RSD5 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab RSD5-Germline Heavy Chain, Fab RSD5-Germline Light Chain, ... 著者 Battles, M.B, McLellan, J.S, Jones, H.J. 登録日 2018-05-04 公開日 2019-07-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.501 Å) 主引用文献 Alternative conformations of a major antigenic site on RSV F. Plos Pathog., 15, 2019
3MMK	The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification 分子名称: CHLORIDE ION, Fusion of LIM/homeobox protein Lhx4, linker, ... 著者 Gadd, M.S, Langley, D.B, Guss, J.M, Matthews, J.M. 登録日 2010-04-20 公開日 2011-07-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.157 Å) 主引用文献 The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification. J.Biol.Chem., 2011
3M3T	SARS-CoV main protease monomeric Arg298Ala mutant with N-terminal additional residues (Gly-Ser) 分子名称: 3C-like proteinase 著者 Shi, J.H, Song, J.X. 登録日 2010-03-10 公開日 2011-03-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 SARS-CoV main protease with N-terminal extension regulated by mutation on C-terminal domain To be Published
3MP4	Crystal structure of Human lyase R41M mutant 分子名称: Hydroxymethylglutaryl-CoA lyase 著者 Fu, Z, Runquist, J.A, Montgomery, C, Miziorko, H.M, Kim, J.-J.P. 登録日 2010-04-24 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Functional insights into human HMG-CoA lyase from structures of Acyl-CoA-containing ternary complexes. J.Biol.Chem., 285, 2010
3M3Z	Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor 分子名称: 5'-O-(2-amino-2-oxoethyl)-8-(methylamino)adenosine, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein 著者 Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. 登録日 2010-03-10 公開日 2011-01-26 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
6QTX	Crystal structure of an Arabidopsis WD40 domain in complex with a flowering transcription factor homolog 分子名称: E3 ubiquitin-protein ligase COP1, GLYCEROL, SULFATE ION, ... 著者 Hothorn, M, Lau, K. 登録日 2019-02-25 公開日 2019-07-10 最終更新日 2019-10-02 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Plant photoreceptors and their signaling components compete for COP1 binding via VP peptide motifs. Embo J., 38, 2019
6QUM	Thermus thermophilus V/A-type ATPase/synthase, rotational state 1 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, V-type ATP synthase alpha chain, ... 著者 Zhou, L, Sazanov, L. 登録日 2019-02-27 公開日 2019-08-28 最終更新日 2020-09-30 実験手法 ELECTRON MICROSCOPY (3.25 Å) 主引用文献 Structure and conformational plasticity of the intact Thermus thermophilus V/A-type ATPase. Science, 365, 2019
6DU5	Crystal structure of hMettl16 catalytic domain in complex with MAT2A 3'UTR hairpin 6 分子名称: U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase, hp6-RNA (25-MER) 著者 Doxtader, K, Wang, P, Nam, Y. 登録日 2018-06-19 公開日 2018-09-26 最終更新日 2018-10-03 実験手法 X-RAY DIFFRACTION (3.006 Å) 主引用文献 Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor. Mol. Cell, 71, 2018
3MSL	Fragment Based Discovery and Optimisation of BACE-1 Inhibitors 分子名称: (3S)-3-(2-amino-5-chloro-1H-benzimidazol-1-yl)-N-(cyclohexylmethyl)pentanamide, Beta-secretase 1, IODIDE ION 著者 Smith, M, Madden, J, Barker, J. 登録日 2010-04-29 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Fragment-based discovery and optimization of BACE1 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
6QSZ	Crystal structure of the Sir4 H-BRCT domain in complex with Esc1 pS1450 peptide 分子名称: CHLORIDE ION, Regulatory protein SIR4, Silent chromatin protein ESC1 著者 Deshpande, I, Keusch, J.J, Challa, K, Iesmantavicius, V, Gasser, S.M, Gut, H. 登録日 2019-02-22 公開日 2019-09-18 最終更新日 2019-10-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin. Embo J., 38, 2019
3M0B	Ru-Porphyrin Protein Scaffolds for Sensing O2 分子名称: CARBON MONOXIDE, Methyl-accepting chemotaxis protein, [3,3'-(7,12-diethyl-3,8,13,17-tetramethylporphyrin-2,18-diyl-kappa~4~N~21~,N~22~,N~23~,N~24~)dipropanoato(2-)]ruthenium 著者 Winter, M.B, McLaurin, E.J, Reece, S.Y, Olea Jr, C, Nocera, D.G, Marletta, M.A. 登録日 2010-03-02 公開日 2010-04-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ru-porphyrin protein scaffolds for sensing O2. J.Am.Chem.Soc., 132, 2010
3MEC	HIV-1 Reverse Transcriptase in Complex with TMC125 分子名称: 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE, SULFATE ION, p51 Reverse transcriptase, ... 著者 Lansdon, E.B. 登録日 2010-03-31 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of HIV-1 Reverse Transcriptase with Etravirine (TMC125) and Rilpivirine (TMC278): Implications for Drug Design. J.Med.Chem., 53, 2010
6DPS	Crystal Structure of Neisseria meningitidis DsbD n-terminal domain in the oxidised form 分子名称: Thiol:disulfide interchange protein DsbD, ZINC ION 著者 Heras, B, Smith, R.P, Paxman, J.J. 登録日 2018-06-09 公開日 2018-09-12 最終更新日 2018-11-07 実験手法 X-RAY DIFFRACTION (2.556 Å) 主引用文献 Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens. J. Biol. Chem., 293, 2018
3MA2	Complex membrane type-1 matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase-1 (TIMP-1) 分子名称: CALCIUM ION, Matrix metalloproteinase-14, Metalloproteinase inhibitor 1, ... 著者 Grossman, M, Tworowski, D, Dym, O, Lee, M.-H, Levy, Y, Sagi, I. 登録日 2010-03-23 公開日 2010-06-30 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The Intrinsic Protein Flexibility of Endogenous Protease Inhibitor TIMP-1 Controls Its Binding Interface and Affects Its Function. Biochemistry, 49, 2010

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