6QSZ

Crystal structure of the Sir4 H-BRCT domain in complex with Esc1 pS1450 peptide

Summary for 6QSZ

Entry DOI	10.2210/pdb6qsz/pdb
Descriptor	Regulatory protein SIR4, Silent chromatin protein ESC1, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	heterochromatin, nuclear protein
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	16
Total formula weight	134973.60
Authors	Deshpande, I.,Keusch, J.J.,Challa, K.,Iesmantavicius, V.,Gasser, S.M.,Gut, H. (deposition date: 2019-02-22, release date: 2019-09-18, Last modification date: 2019-10-23)
Primary citation	Deshpande, I.,Keusch, J.J.,Challa, K.,Iesmantavicius, V.,Gasser, S.M.,Gut, H. The Sir4 H-BRCT domain interacts with phospho-proteins to sequester and repress yeast heterochromatin. Embo J., 38:e101744-e101744, 2019 Cited by PubMed: 31515872 DOI: 10.15252/embj.2019101744 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation