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2M5Q
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BU of 2m5q by Molmil
Solution structure of lipidated glucagon analog in d-TFE
分子名称: GAMMA-L-GLUTAMIC ACID, Glucagon, PALMITIC ACID
著者Ward, B.P, Ma, D.
登録日2013-03-04
公開日2013-03-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural Changes Associated with Peptide Lipidation Broaden Biological Function
To be Published
2MD2
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BU of 2md2 by Molmil
Fragment based approach and binding behavior of LFampinB with Lipopolysaccharide: biophysical aspects
分子名称: Lactotransferrin
著者Bhunia, A, Chatterjee, S, Ghosh, A, Jana, J.
登録日2013-08-29
公開日2013-09-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Sequence context induced antimicrobial activity: insight into lipopolysaccharide permeabilization.
Mol Biosyst, 10, 2014
2ME8
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BU of 2me8 by Molmil
Solution Structure of BCL-xL in its p53-bound conformation determined with selective isotope labelling of I,L,V sidechains
分子名称: Bcl-2-like protein 1
著者Viacava Follis, A, Grace, C.R, Kriwacki, R.W.
登録日2013-09-25
公開日2014-04-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The DNA-binding domain mediates both nuclear and cytosolic functions of p53.
Nat.Struct.Mol.Biol., 21, 2014
2M58
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BU of 2m58 by Molmil
Structure of 2'-5' AG1 lariat forming ribozyme in its inactive state
分子名称: RNA (59-MER)
著者Carlomagno, T, Amata, I, Codutti, L, Falb, M, Fohrer, J, Simon, B.
登録日2013-02-18
公開日2013-04-03
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural principles of RNA catalysis in a 2'-5' lariat-forming ribozyme.
J.Am.Chem.Soc., 135, 2013
2M92
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BU of 2m92 by Molmil
Structure of d[AGGGTGGGTGCTGGGGCGCGAAGCATTCGCGAGG] quadruplex-duplex hybrid
分子名称: 34-MER DNA
著者Lim, K.W, Phan, A.T.
登録日2013-05-30
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA quadruplex-duplex junction formation.
Angew.Chem.Int.Ed.Engl., 52, 2013
2M1H
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BU of 2m1h by Molmil
Solution structure of a PWWP domain from Trypanosoma brucei
分子名称: Transcription elongation factor S-II
著者Wang, R, Fan, K, Liao, S, Zhang, J, Tu, X.
登録日2012-11-28
公開日2013-12-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of TbTFIIS2-1 PWWP domain from Trypanosoma brucei.
Proteins, 84, 2016
2LV3
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BU of 2lv3 by Molmil
Structure-functional characterization of Grx domain of Mus musculus TGR
分子名称: Thioredoxin reductase 3
著者Dobrovolska, O, Shumilina, E, Gladyshev, V, Dikiy, A.
登録日2012-06-28
公開日2013-05-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural analysis of glutaredoxin domain of Mus musculus thioredoxin glutathione reductase
Plos One, 7, 2012
2M91
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BU of 2m91 by Molmil
Structure of d[GGGAAGGGCGCGAAGCATTCGCGAGGTAGG] quadruplex-duplex hybrid
分子名称: 30-MER DNA
著者Lim, K.W, Phan, A.T.
登録日2013-05-30
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA quadruplex-duplex junction formation.
Angew.Chem.Int.Ed.Engl., 52, 2013
2M90
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BU of 2m90 by Molmil
Structure of d[GCGCGAAGCATTCGCGGGGAGGTGGGGAAGGG] quadruplex-duplex hybrid
分子名称: 32-MER DNA
著者Lim, K.W, Phan, A.T.
登録日2013-05-30
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA quadruplex-duplex junction formation.
Angew.Chem.Int.Ed.Engl., 52, 2013
2MJR
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BU of 2mjr by Molmil
Anoplin R5W structure in DPC micelles
分子名称: Anoplin, UNKNOWN ATOM OR ION, dodecyl 2-(trimethylammonio)ethyl phosphate
著者Uggerhoej, L, Poulsen, T.J, Wimmer, R.
登録日2014-01-16
公開日2014-12-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Rational Design of Alpha-Helical Antimicrobial Peptides: Do's and Don'ts.
Chembiochem, 16, 2015
2M8I
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BU of 2m8i by Molmil
Structure of Pin1 WW domain
分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Luh, L.M, Kirchner, D.K, Loehr, F, Haensel, R, Doetsch, V.
登録日2013-05-22
公開日2014-04-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition.
J.Am.Chem.Soc., 135, 2013
2M8Y
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BU of 2m8y by Molmil
Structure of d[CGCGAAGCATTCGCG] hairpin
分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*GP*CP*AP*TP*TP*CP*GP*CP*G)-3')
著者Lim, K.W, Phan, A.T.
登録日2013-05-30
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis of DNA quadruplex-duplex junction formation.
Angew.Chem.Int.Ed.Engl., 52, 2013
6BFX
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BU of 6bfx by Molmil
BACE crystal structure with hydroxy pyrrolidine inhibitor
分子名称: Beta-secretase 1, GLYCEROL, N-{(1S,2S)-3-(3,5-difluorophenyl)-1-[(3R,5S,6R)-6-(2,2-dimethylpropoxy)-5-methylmorpholin-3-yl]-1-hydroxypropan-2-yl}acetamide
著者Timm, D.E.
登録日2017-10-27
公開日2017-11-15
最終更新日2017-12-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.
J. Med. Chem., 60, 2017
6BFE
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BU of 6bfe by Molmil
BACE crystal structure with hydroxy pyrrolidine inhibitor
分子名称: Beta-secretase 1, GLYCEROL, N-[(1R,2S)-1-[(2R,4R)-4-(cyclohexylmethoxy)pyrrolidin-2-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide
著者Timm, D.E.
登録日2017-10-26
公開日2017-11-15
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.
J. Med. Chem., 60, 2017
6BFD
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BU of 6bfd by Molmil
BACE crystal structure with hydroxy pyrrolidine inhibitor
分子名称: 2-{[(2S)-butan-2-yl]amino}-N-{(1R,2S)-1-hydroxy-3-phenyl-1-[(2R)-pyrrolidin-2-yl]propan-2-yl}-6-(methylsulfonyl)pyridine-4-carboxamide, Beta-secretase 1, GLYCEROL
著者Timm, D.E.
登録日2017-10-26
公開日2017-11-15
最終更新日2017-12-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.
J. Med. Chem., 60, 2017
6BFW
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BU of 6bfw by Molmil
BACE crystal structure with hydroxy morpholine inhibitor
分子名称: Beta-secretase 1, GLYCEROL, N-[(1S,2S)-1-[(3R,6R)-6-(cyclohexylmethoxy)morpholin-3-yl]-3-(3,5-difluorophenyl)-1-hydroxypropan-2-yl]acetamide
著者Timm, D.E.
登録日2017-10-27
公開日2017-11-15
最終更新日2017-12-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.
J. Med. Chem., 60, 2017
2BIO
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BU of 2bio by Molmil
human p53 core domain mutant M133L-V203A-N239Y-R249S-N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIP
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BU of 2bip by Molmil
human p53 core domain mutant M133L-H168R-V203A-N239Y-R249S-N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIN
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BU of 2bin by Molmil
human p53 core domain mutant M133L-H168R-V203A-N239Y-N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIM
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BU of 2bim by Molmil
human p53 core domain mutant M133L-V203A-N239Y-N268D-R273H
分子名称: CELLULAR TUMOR ANTIGEN P53, SULFATE ION, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
2BIQ
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BU of 2biq by Molmil
human p53 core domain mutant T123A-M133L-H168R-V203A-N239Y-R249S- N268D
分子名称: CELLULAR TUMOR ANTIGEN P53, ZINC ION
著者Joerger, A.C, Fersht, A.R.
登録日2005-01-25
公開日2005-01-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of P53 Cancer Mutants and Mechanism of Rescue by Second-Site Suppressor Mutations
J.Biol.Chem., 280, 2005
4WRQ
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BU of 4wrq by Molmil
Crystal Structure of 14-3-3 zeta with Chibby peptide
分子名称: 14-3-3 protein zeta/delta, Chibby
著者Killoran, R.C, Shilton, B.H, Choy, W.Y.
登録日2014-10-24
公開日2015-05-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.409 Å)
主引用文献Structural Analysis of the 14-3-3 zeta /Chibby Interaction Involved in Wnt/ beta-Catenin Signaling.
Plos One, 10, 2015
4KEJ
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BU of 4kej by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R169Q
分子名称: Ryanodine receptor 2
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.553 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEI
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BU of 4kei by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S
分子名称: Ryanodine receptor 2
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013
4KEK
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BU of 4kek by Molmil
Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R176Q
分子名称: Ryanodine receptor 2, SULFATE ION
著者Kimlicka, L, Van Petegem, F.
登録日2013-04-25
公開日2013-09-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.146 Å)
主引用文献Type 2 Ryanodine Receptor Domain A Contains a Unique and Dynamic alpha-Helix That Transitions to a beta-Strand in a Mutant Linked with a Heritable Cardiomyopathy.
J.Mol.Biol., 425, 2013

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