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2IWM
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BU of 2iwm by Molmil
precursor mutant Cys1Ser of Penicillin V Acylase from Bacillus sphaericus
分子名称: PENICILLIN ACYLASE
著者Chandra, P.M, Dodson, G, Suresh, C.G.
登録日2006-07-01
公開日2007-08-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Precursor Mutant Cys1Ser of Penicillin V Acylase from Bacilus Sphaericus
To be Published
2IXV
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BU of 2ixv by Molmil
Crystal structure of the modular Cpl-1 endolysin complexed with a peptidoglycan analogue (E94Q mutant)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-alpha-muramic acid, ALANINE, D-GLUTAMINE, ...
著者Perez-Dorado, I, Hermoso, J.A.
登録日2006-07-11
公開日2007-07-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Elucidation of the Molecular Recognition of Bacterial Cell Wall by Modular Pneumococcal Phage Endolysin Cpl-1.
J.Biol.Chem., 282, 2007
6DI4
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BU of 6di4 by Molmil
Rational Modification of Vanillin Derivatives to Stereospecifically Destabilize Sickle Hemoglobin Polymer Formation
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Pagare, P.P, Musayev, F.N.
登録日2018-05-22
公開日2018-09-05
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Rational modification of vanillin derivatives to stereospecifically destabilize sickle hemoglobin polymer formation.
Acta Crystallogr D Struct Biol, 74, 2018
6O6C
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BU of 6o6c by Molmil
RNA polymerase II elongation complex arrested at a CPD lesion
分子名称: DNA (27-MER), DNA (5'-D(P*GP*GP*AP*GP*AP*AP*GP*GP*AP*GP*CP*AP*GP*AP*GP*C)-3'), DNA-directed RNA polymerase II subunit RPB1, ...
著者Lahiri, I, Leshziner, A.E.
登録日2019-03-05
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献3.1 angstrom structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids.
J.Struct.Biol., 207, 2019
6OD7
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BU of 6od7 by Molmil
Herpes simplex virus type 1 (HSV-1) pUL6 portal protein, dodecameric complex
分子名称: Portal protein
著者Liu, Y.T, Jih, J, Dai, X.H, Bi, G.Q, Zhou, Z.H.
登録日2019-03-26
公開日2019-06-19
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Cryo-EM structures of herpes simplex virus type 1 portal vertex and packaged genome.
Nature, 570, 2019
8JND
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BU of 8jnd by Molmil
The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-06
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
8JNE
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BU of 8jne by Molmil
The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome without the linker DNA binding
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-06
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.68 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
8JNF
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BU of 8jnf by Molmil
The cryo-EM structure of the RAD51 filament bound to the nucleosome
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-06-06
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.91 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
3LNX
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BU of 3lnx by Molmil
Second PDZ domain from human PTP1E
分子名称: IODIDE ION, THIOCYANATE ION, Tyrosine-protein phosphatase non-receptor type 13
著者Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2010-02-03
公開日2010-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.642 Å)
主引用文献Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010
5XM0
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BU of 5xm0 by Molmil
The mouse nucleosome structure containing H2A, H2B type3-A, H3.3, and H4
分子名称: DNA (146-MER), Histone H2A type 1-B, Histone H2B type 3-A, ...
著者Taguchi, H, Horikoshi, N, Kurumizaka, H.
登録日2017-05-12
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.874 Å)
主引用文献Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration.
Nat Commun, 9, 2018
5XNF
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BU of 5xnf by Molmil
Crystal structure of the branched-chain polyamine synthase (BpsA) from Thermococcus kodakarensis
分子名称: FE (III) ION, GLYCEROL, N(4)-bis(aminopropyl)spermidine synthase, ...
著者Mizohata, E, Tse, K.M, Fujita, J, Inoue, T.
登録日2017-05-22
公開日2018-08-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine.
FEBS J., 284, 2017
5K9M
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BU of 5k9m by Molmil
Crystal Structure of PriB Binary Complex with Product Diphosphate
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYROPHOSPHATE 2-, PriB Prenyltransferase
著者Cao, H, Elshahawi, S, Benach, J, Wasserman, S.R, Morisco, L.L, Koss, J.W, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2016-06-01
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure and specificity of a permissive bacterial C-prenyltransferase.
Nat. Chem. Biol., 13, 2017
6OQQ
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BU of 6oqq by Molmil
Legionella pneumophila SidJ/Saccharomyces cerevisiae calmodulin complex
分子名称: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, CALCIUM ION, ...
著者Tomchick, D.R, Tagliabracci, V.S, Black, M, Osinski, A.
登録日2019-04-28
公開日2019-05-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases.
Science, 364, 2019
4XUI
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BU of 4xui by Molmil
Crystal structure analysis of cruzain bound to the no-covalent analog of WRR-483 (WRR-669)
分子名称: 1,2-ETHANEDIOL, Cruzipain, N-[(2S)-5-(carbamimidamidooxy)-1-oxo-1-{[(1E,3S)-5-phenyl-1-(pyrimidin-2-ylsulfonyl)pent-1-en-3-yl]amino}pentan-2-yl]-4-methylpiperazine-1-carboxamide
著者Tochowicz, A, McKerrow, J.H.
登録日2015-01-26
公開日2015-03-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.508 Å)
主引用文献Synthesis and Evaluation of Oxyguanidine Analogues of the Cysteine Protease Inhibitor WRR-483 against Cruzain.
Acs Med.Chem.Lett., 7, 2016
5XNH
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BU of 5xnh by Molmil
Crystal structure of the branched-chain polyamine synthase (BpsA) in complex with spermidine
分子名称: FE (III) ION, N(4)-bis(aminopropyl)spermidine synthase, SPERMIDINE
著者Mizohata, E, Tse, K.M, Fujita, J, Inoue, T.
登録日2017-05-22
公開日2017-10-04
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine.
FEBS J., 284, 2017
5J43
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BU of 5j43 by Molmil
CdiA-CT from uropathogenic Escherichia coli in complex with CysK
分子名称: Cysteine synthase A, tRNA nuclease CdiA
著者Morse, R.P, Goulding, C.W, Johnson, P.M.
登録日2016-03-31
公開日2016-07-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Unraveling the essential role of CysK in CDI toxin activation.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4KLB
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BU of 4klb by Molmil
Crystal Structure of Cruzain in complex with the non-covalent inhibitor Nequimed176
分子名称: 2-{[(1H-1,2,4-triazol-5-ylsulfanyl)acetyl]amino}thiophene-3-carboxamide, Cruzipain
著者Fernandes, W.B, Montanari, C.A, Mckerrow, J.H.
登録日2013-05-07
公開日2013-09-18
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Non-peptidic Cruzain Inhibitors with Trypanocidal Activity Discovered by Virtual Screening and In Vitro Assay.
Plos Negl Trop Dis, 7, 2013
6ESG
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BU of 6esg by Molmil
Nucleosome breathing : Class 2
分子名称: DNA (141-MER), Histone H2A, Histone H2B 1.1, ...
著者Bilokapic, S, Halic, M.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
3LNY
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BU of 3lny by Molmil
Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide
分子名称: Rap guanine nucleotide exchange factor 6, SULFATE ION, THIOCYANATE ION, ...
著者Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2010-02-03
公開日2010-03-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010
6ESH
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BU of 6esh by Molmil
Nucleosome breathing : Class 3
分子名称: DNA (137-MER), Histone H2A, Histone H2B 1.1, ...
著者Bilokapic, S, Halic, M.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
5XNC
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BU of 5xnc by Molmil
Crystal structure of the branched-chain polyamine synthase (BpsA) in complex with N4-aminopropylspermidine and 5-methylthioadenosine
分子名称: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, DI(HYDROXYETHYL)ETHER, ...
著者Mizohata, E, Tse, K.M, Fujita, J, Inoue, T.
登録日2017-05-22
公開日2018-08-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine.
FEBS J., 284, 2017
6ESI
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BU of 6esi by Molmil
Nucleosome breathing : Class 4
分子名称: DNA (133-MER), Histone H2A, Histone H2B 1.1, ...
著者Bilokapic, S, Halic, M.
登録日2017-10-20
公開日2017-12-20
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Histone octamer rearranges to adapt to DNA unwrapping.
Nat. Struct. Mol. Biol., 25, 2018
5XY3
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BU of 5xy3 by Molmil
Large subunit of Trichomonas vaginalis ribosome
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N.
登録日2017-07-06
公開日2017-08-30
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
8FKY
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BU of 8fky by Molmil
Human nucleolar pre-60S ribosomal subunit (State F)
分子名称: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L10a, ...
著者Vanden Broeck, A, Klinge, S.
登録日2022-12-21
公開日2023-07-12
最終更新日2023-07-19
実験手法ELECTRON MICROSCOPY (2.67 Å)
主引用文献Principles of human pre-60 S biogenesis.
Science, 381, 2023
7KLP
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BU of 7klp by Molmil
Crystal structure of a three-tetrad, parallel, K+ stabilized human telomeric G-quadruplex
分子名称: HEXAETHYLENE GLYCOL, POTASSIUM ION, telomeric DNA
著者Yatsunyk, L.A, Li, K.S, Chen, E.V.
登録日2020-10-30
公開日2020-12-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Water spines and networks in G-quadruplex structures.
Nucleic Acids Res., 49, 2021

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件を2024-09-11に公開中

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