3LNY

Second PDZ domain from human PTP1E in complex with RA-GEF2 peptide

Summary for 3LNY

• Entry DOI: 10.2210/pdb3lny/pdb
• Descriptor: Tyrosine-protein phosphatase non-receptor type 13, Rap guanine nucleotide exchange factor 6, THIOCYANATE ION, ... (5 entities in total)
• Functional Keywords: pdz2, structural genomics, protein structure initiative, psi-2, center for eukaryotic structural genomics, cesg, cytoskeleton, cell membrane, guanine-nucleotide releasing factor, signaling protein-signaling protein complex, signaling protein/signaling protein
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton : Q12923; Cytoplasm : Q8TEU7
• Total number of polymer chains: 2
• Total formula weight: 10902.14

Authors

Zhang, J.,Chang, A.,Ke, H.,Phillips Jr., G.N.,Lee, A.L.,Center for Eukaryotic Structural Genomics (CESG) (deposition date: 2010-02-03, release date: 2010-03-23, Last modification date: 2024-02-21)

• Primary citation: Zhang, J.,Sapienza, P.J.,Ke, H.,Chang, A.,Hengel, S.R.,Wang, H.,Phillips, G.N.,Lee, A.L.; Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.; Biochemistry, 49:9280-9291, 2010; PubMed: 20839809; DOI: 10.1021/bi101131f

Experimental method

X-RAY DIFFRACTION (1.3 Å)