PDB: 45176 件ウェブページステータス検索Chemie searchBIRD

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5IF0	Crystal structure of VRC01c-HuGL2 Fab from an HIV-1 naive donor in complex with with a germline-targeting gp120 engineered outer domain eOD-GT8 at 2.44 A 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain eOD-GT8, PHOSPHATE ION, ... 著者 Sarkar, A, Wilson, I.A. 登録日 2016-02-25 公開日 2016-04-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen. Science, 351, 2016
5I7F	Crystal structure of B. pseudomallei FabI in complex with NAD and PT405 分子名称: 5-ethyl-4-fluoro-2-(2-fluorophenoxy)phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Eltschkner, S, Tonge, P.J, Kisker, C. 登録日 2016-02-17 公開日 2017-02-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Rationalizing the Binding Kinetics for the Inhibition of the Burkholderia pseudomallei FabI1 Enoyl-ACP Reductase. Biochemistry, 56, 2017
5I43	Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelator water-soluble inhibitor (DC32). 分子名称: (2R)-2-[({1-[3-({(2R,3R,4R,5S,6R)-3-(acetylamino)-4,5-bis(acetyloxy)-6-[(acetyloxy)methyl]tetrahydro-2H-pyran-2-yl}oxy)propyl]-1H-1,2,3-triazol-4-yl}methyl)(biphenyl-4-ylsulfonyl)amino]-3-methylbutanoic acid (non-preferred name), 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A. 登録日 2016-02-11 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors. Chemmedchem, 11, 2016
3IT8	Crystal structure of TNF alpha complexed with a poxvirus MHC-related TNF binding protein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2L protein, Tumor necrosis factor 著者 Yang, Z, West Jr, A.P, Bjorkman, P.J. 登録日 2009-08-27 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of TNFalpha complexed with a poxvirus MHC-related TNF binding protein Nat.Struct.Mol.Biol., 16, 2009
4XY7	Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with N-acetylglucosamine at 2.5 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ribosome inactivating protein 著者 Yamini, S, Pandey, S, Kaur, P, Sharma, S, Singh, T.P. 登録日 2015-02-02 公開日 2015-09-23 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the complex of ribosome inactivating protein from Momordica balsamina with N- acetylglucosamine at 2.5 A resolution To Be Published
4XYK	Crystal structure of human phosphofructokinase-1 in complex with ADP, Northeast Structural Genomics Consortium Target HR9275 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent 6-phosphofructokinase, platelet type, ... 著者 Forouhar, F, Webb, B.A, Szu, F.-E, Seetharaman, J, Barber, D.L, Tong, L, Northeast Structural Genomics Consortium (NESG) 登録日 2015-02-02 公開日 2015-05-06 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structures of human phosphofructokinase-1 and atomic basis of cancer-associated mutations. Nature, 523, 2015
6COX	CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A SELECTIVE INHIBITOR, SC-558 IN I222 SPACE GROUP 分子名称: 1-PHENYLSULFONAMIDE-3-TRIFLUOROMETHYL-5-PARABROMOPHENYLPYRAZOLE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOOXYGENASE-2, ... 著者 Kurumbail, R, Stallings, W. 登録日 1996-12-18 公開日 1997-12-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature, 384, 1996
6CGT	HOXA COMPLEX OF CYCLODEXTRIN GLYCOSYLTRANSFERASE MUTANT 分子名称: 4-amino-4,6-dideoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose, CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE, ... 著者 Parsiegla, G, Schulz, G.E. 登録日 1998-06-06 公開日 1998-10-14 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Substrate binding to a cyclodextrin glycosyltransferase and mutations increasing the gamma-cyclodextrin production. Eur.J.Biochem., 255, 1998
8AAC	African cichlid nackednavirus capsid at pH 7.5 分子名称: C protein 著者 Pfister, S, Rabl, J, Boehringer, D, Meier, B.H. 登録日 2022-07-01 公開日 2023-04-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style. Nat Commun, 14, 2023
4YAU	Reduced CYPOR mutant - G141del/E142N 分子名称: ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Xia, C, Kim, J.J.P. 登録日 2015-02-17 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone. J.Biol.Chem., 291, 2016
4YN3	Crystal structure of Cucumisin complex with pro-peptide 分子名称: CHLORIDE ION, Cucumisin, DI(HYDROXYETHYL)ETHER, ... 著者 Murayama, K, Kato-Murayama, M, Yokoyama, S, Arima, K, Shirouzu, M. 登録日 2015-03-09 公開日 2016-03-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis of cucumisin protease activity regulation by its propeptide J. Biochem., 161, 2017
4YVF	Structure of S-adenosyl-L-homocysteine hydrolase 分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-{[5-chloro-2-(4-chlorophenoxy)phenyl](2-{[2-(methylamino)ethyl]amino}-2-oxoethyl)amino}-N-(1,3-dihydro-2H-isoindol-2-yl)-N-methylacetamide, Adenosylhomocysteinase 著者 Akiko, K. 登録日 2015-03-20 公開日 2015-11-25 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery and structural analyses of S-adenosyl-L-homocysteine hydrolase inhibitors based on non-adenosine analogs. Bioorg.Med.Chem., 23, 2015
4Y9U	rat CYPOR mutant - G143del 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Xia, C, Kim, J.J.P. 登録日 2015-02-17 公開日 2016-03-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone. J.Biol.Chem., 291, 2016
6BOK	E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Korostelev, A.A. 登録日 2017-11-20 公開日 2018-05-23 最終更新日 2019-12-25 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Conformational Control of Translation Termination on the 70S Ribosome. Structure, 26, 2018
3KLF	Crystal structure of wild-type HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA 分子名称: DNA (5'-D(*A*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(2DA))-3'), DNA (5'-D(*AP*T*GP*CP*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*GP*TP*G)-3'), GLYCEROL, ... 著者 Tu, X, Das, K, Sarafianos, S.G, Arnold, E. 登録日 2009-11-07 公開日 2010-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Structural basis of HIV-1 resistance to AZT by excision. Nat.Struct.Mol.Biol., 17, 2010
6CP4	P450CAM D251N MUTANT 分子名称: CAMPHOR, CYTOCHROME P450CAM, GLYCEROL, ... 著者 Li, H, Poulos, T.L. 登録日 1998-05-28 公開日 1998-09-16 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Understanding the role of the essential Asp251 in cytochrome p450cam using site-directed mutagenesis, crystallography, and kinetic solvent isotope effect. Biochemistry, 37, 1998
3KLE	Crystal structure of AZT-resistant HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA 分子名称: DNA (25-MER), DNA (5'-D(*AP*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)P*CP*GP*CP*CP*(2DA))-3'), GLYCEROL, ... 著者 Tu, X, Das, K, Sarafianos, S.G, Arnold, E. 登録日 2009-11-07 公開日 2010-09-22 最終更新日 2021-10-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis of HIV-1 resistance to AZT by excision. Nat.Struct.Mol.Biol., 17, 2010
4Y7C	rat CYPOR mutant - G141del/E142N 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Xia, C, Kim, J.J.P. 登録日 2015-02-13 公開日 2016-02-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone. J.Biol.Chem., 291, 2016
4YAF	rat CYPOR with 2'-AMP 分子名称: ADENOSINE-2'-MONOPHOSPHATE, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Xia, C, Kim, J.J.P. 登録日 2015-02-17 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone. J.Biol.Chem., 291, 2016
4YK8	Crystal structure of the Atg101-Atg13 complex from fission yeast 分子名称: Autophagy protein 13, Meiotically up-regulated gene 66 protein 著者 Suzuki, H, Noda, N.N. 登録日 2015-03-04 公開日 2015-06-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiation. Nat.Struct.Mol.Biol., 22, 2015
4YWU	Structural insight into the substrate inhibition mechanism of NADP+-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes 分子名称: 4-oxobutanoic acid, SULFATE ION, Succinic semialdehyde dehydrogenase 著者 Jang, E.H, Park, S.A, Chi, Y.M, Lee, K.S. 登録日 2015-03-21 公開日 2015-05-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insight into the substrate inhibition mechanism of NADP(+)-dependent succinic semialdehyde dehydrogenase from Streptococcus pyogenes. Biochem.Biophys.Res.Commun., 461, 2015
4Y9R	rat CYPOR mutant - G141del 分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Xia, C, Kim, J.J.P. 登録日 2015-02-17 公開日 2016-03-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone. J.Biol.Chem., 291, 2016
6CZ2	Structure of the PTK6 kinase domain 分子名称: Protein-tyrosine kinase 6 著者 Gajiwala, K.S, Johnson, E, Cronin, C.N. 登録日 2018-04-07 公開日 2018-06-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Small molecule inhibitors reveal PTK6 kinase is not an oncogenic driver in breast cancers. PLoS ONE, 13, 2018
4WQT	Thermus thermophilus RNA polymerase complexed with an RNA cleavage stimulating factor (a GreA/Gfh1 chimeric protein) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murayama, Y, Sekine, S, Yokoyama, S. 登録日 2014-10-22 公開日 2015-02-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 The Ratcheted and Ratchetable Structural States of RNA Polymerase Underlie Multiple Transcriptional Functions. Mol.Cell, 57, 2015
5NSE	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE, H4B-FREE, HYDROXY-ARG COMPLEX 分子名称: ACETATE ION, CACODYLIC ACID, GLYCEROL, ... 著者 Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L. 登録日 1999-01-13 公開日 2002-05-29 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structures of the Heme Domain of Bovine Endothelial Nitric Oxide Synthase Complexed with Arginine Analogues To be Published

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