PDB: 41522 件ウェブページステータス検索Chemie searchBIRD

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6E0K	Structure of Rhodothermus marinus CdnE c-UMP-AMP synthase 分子名称: cGAS/DncV-like nucleotidyltransferase in E. coli homolog 著者 Eaglesham, J.B, Whiteley, A.T, de Oliveira Mann, C.C, Morehouse, B.R, Nieminen, E.A, King, D.S, Lee, A.S.Y, Mekalanos, J.J, Kranzusch, P.J. 登録日 2018-07-06 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567, 2019
4UP3	Crystal structure of the mutant C140S,C286Q thioredoxin reductase from Entamoeba histolytica 分子名称: 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Podust, L.M, Vieira, D.F. 登録日 2014-06-11 公開日 2015-07-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action. J.Struct.Biol., 194, 2016
4UF6	UCH-L5 in complex with ubiquitin-propargyl bound to an activating fragment of INO80G 分子名称: NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN, POLYUBIQUITIN-B, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 著者 Sahtoe, D.D, Van Dijk, W.J, El Oualid, F, Ekkebus, R, Ovaa, H, Sixma, T.K. 登録日 2014-12-23 公開日 2015-03-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.69 Å) 主引用文献 Mechanism of Uch-L5 Activation and Inhibition by Deubad Domains in Rpn13 and Ino80G. Mol.Cell, 57, 2015
4UI6	Crystal structure of human tankyrase 2 in complex with TA-47 分子名称: 8-METHOXY-2-[4-(TRIFLUOROMETHYL)PHENYL]-3,4-DIHYDROQUINAZOLIN-4-ONE, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
2REJ	ABC-transporter choline binding protein in unliganded semi-closed conformation 分子名称: PUTATIVE GLYCINE BETAINE ABC TRANSPORTER PROTEIN 著者 Oswald, C, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Le Rudulier, D, Schmitt, L, Bremer, E. 登録日 2007-09-26 公開日 2008-09-16 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states. J.Biol.Chem., 283, 2008
4UMK	The complex of Spo0J and parS DNA in chromosomal partition system 分子名称: DNA, PROBABLE CHROMOSOME-PARTITIONING PROTEIN PARB, SULFATE ION 著者 Chen, B.W, Chu, C.H, Tung, J.Y, Hsu, C.E, Hsiao, C.D, Sun, Y.J. 登録日 2014-05-19 公開日 2015-05-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.096 Å) 主引用文献 Insights into ParB spreading from the complex structure of Spo0J and parS. Proc. Natl. Acad. Sci. U.S.A., 112, 2015
2REX	Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase 分子名称: CALCIUM ION, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Tong, Y, Tempel, W, Shen, L, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2007-09-27 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the effector domain of PLXNB1 bound with Rnd1 GTPase. To be Published
4PVH	Phl p 4 N158H variant, a glucose dehydrogenase 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, Pollen allergen Phl p 4.0202, ... 著者 Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. 登録日 2014-03-17 公開日 2014-04-02 最終更新日 2015-09-02 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
6E18	Crystal structure of Chlamydomonas reinhardtii HAP2 ectodomain provides structural insights of functional loops in green algae. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Baquero, E, Legrand, P, Rey, F.A. 登録日 2018-07-09 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies. Structure, 27, 2019
4UIC	Crystal structure of the S-layer protein rSbsC(31-844) 分子名称: SURFACE LAYER PROTEIN 著者 Pavkov-Keller, T, Dordic, A, Egelseer, E.M, Sleytr, U.B, Keller, W. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 S-Layer Protein Rsbsc(31-844) To be Published
4UI8	Crystal structure of human tankyrase 2 in complex with TA-55 分子名称: 8-HYDROXY-2-[4-(TRIFLUOROMETHYL)PHENYL]-3,4-DIHYDROQUINAZOLIN-4-ONE, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
4UI5	Crystal structure of human tankyrase 2 in complex with TA-41 分子名称: 8-methoxy-2-(4-methylphenyl)-3,4-dihydroquinazolin-4-one, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
6E0O	Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase with pppA[3'-5']pA 分子名称: MAGNESIUM ION, RNA (5'-D(*(ATP))-R(P*A)-3'), cGAS/DncV-like nucleotidyltransferase in E. coli homolog 著者 Eaglesham, J.B, Whiteley, A.T, de Oliveira Mann, C.C, Morehouse, B.R, Nieminen, E.A, King, D.S, Lee, A.S.Y, Mekalanos, J.J, Kranzusch, P.J. 登録日 2018-07-06 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Bacterial cGAS-like enzymes synthesize diverse nucleotide signals. Nature, 567, 2019
2R8F	Crystal structure of H225A NSP2 and ATP-gS complex 分子名称: Non-structural RNA-binding protein 35, PHOSPHATE ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER 著者 Kumar, M, Prasad, B.V.V. 登録日 2007-09-10 公開日 2007-10-23 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallographic and Biochemical Analysis of Rotavirus NSP2 with Nucleotides Reveals a Nucleoside Diphosphate Kinase-Like Activity J.Virol., 81, 2007
4UI4	Crystal structure of human tankyrase 2 in complex with TA-29 分子名称: BENZYL N-{[4-(4-OXO-3,4-DIHYDROQUINAZOLIN-2-YL)PHENYL]METHYL}CARBAMATE, SULFATE ION, TANKYRASE-2, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
4UI3	Crystal structure of human tankyrase 2 in complex with TA-26 分子名称: 2-[4-(trifluoromethyl)phenyl]-3H-quinazolin-4-one, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
2RKT	Crystal Structure of apo F. graminearum TRI101 分子名称: Trichothecene 3-O-acetyltransferase 著者 Garvey, G.S, Rayment, I. 登録日 2007-10-17 公開日 2007-12-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT J.Biol.Chem., 283, 2008
2RB3	Crystal Structure of Human Saposin D 分子名称: GLYCEROL, Proactivator polypeptide, SULFATE ION 著者 Maier, T, Rossman, M, Saenger, W. 登録日 2007-09-18 公開日 2008-04-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of human saposins C and d: implications for lipid recognition and membrane interactions. Structure, 16, 2008
8FY0	E3:PROTAC:target ternary complex structure (VCB/753b/BCL-xL) 分子名称: Bcl-2-like protein 1, CACODYLIC ACID, Elongin-B, ... 著者 Olsen, S.K, Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D. 登録日 2023-01-25 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
8FY1	E3:PROTAC:target ternary complex structure (VCB/753b/BCL-2) 分子名称: Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... 著者 Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. 登録日 2023-01-25 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
4UI7	Crystal structure of human tankyrase 2 in complex with TA-49 分子名称: 8-HYDROXY-2-(4-METHYLPHENYL)-3,4-DIHYDROQUINAZOLIN-4-ONE, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2015-03-27 公開日 2016-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases. Eur.J.Med.Chem., 118, 2016
8FY2	E3:PROTAC:target ternary complex structure (VCB/WH244/BCL-2) 分子名称: Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... 著者 Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Ruben, E, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. 登録日 2023-01-25 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
4V2B	rat Unc5D Ig domain 1 分子名称: PROTEIN UNC5D 著者 Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R. 登録日 2014-10-08 公開日 2014-11-05 最終更新日 2015-07-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development Neuron, 84, 2014
2M18	Structure of stacked G-quadruplex formed by human TERRA sequence in potassium solution 分子名称: RNA (5'-R(*GP*GP*GP*UP*UP*AP*GP*GP*GP*U)-3') 著者 Martadinata, H, Phan, A.T. 登録日 2012-11-20 公開日 2013-04-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure of Human Telomeric RNA (TERRA): Stacking of Two G-Quadruplex Blocks in K(+) Solution Biochemistry, 52, 2013
4V7F	Arx1 pre-60S particle. 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R. 登録日 2013-12-10 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (8.7 Å) 主引用文献 60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle. Nat Commun, 5, 2014

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