PDB: 55698 件ウェブページステータス検索Chemie searchBIRD

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5OJY	Co-complex structure of regulator protein 2 (PamR2) with pamamycin 607 from Streptomyces alboniger 分子名称: CITRIC ACID, GLYCEROL, Pamamycin 607, ... 著者 Schmelz, S, Rebets, Y, Luzhetskyy, A, Scrima, A. 登録日 2017-07-24 公開日 2018-04-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Design, development and application of whole-cell based antibiotic-specific biosensor. Metab. Eng., 47, 2018
1TDB	STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE 分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE 著者 Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M. 登録日 1993-02-15 公開日 1993-07-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate. Biochemistry, 32, 1993
1BJ9	EFFECT OF UNNATURAL HEME SUBSTITUTION ON KINETICS OF ELECTRON TRANSFER IN CYTOCHROME C PEROXIDASE 分子名称: CYTOCHROME C PEROXIDASE, [7,12-DEACETYL-3,8,13,17-TETRAMETHYL-21H,23H-PORPHINE-2,18-DIPROPANOATO(2-)-N21,N22,N23,N24]-IRON 著者 Miller, M.A, Kraut, J. 登録日 1998-07-03 公開日 1999-01-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Effect of Unnatural Heme Substitution on Kinetics of Electron Transfer in Cytochrome C Peroxidase To be Published
5OY7	Structure of the 4_601_157 tetranucleosome (P1 form) 分子名称: CHLORIDE ION, DNA (619-MER), Histone H2A, ... 著者 Ekundayo, B, Richmond, T.J, Schalch, T. 登録日 2017-09-07 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (5.774 Å) 主引用文献 Capturing Structural Heterogeneity in Chromatin Fibers. J. Mol. Biol., 429, 2017
1V54	Bovine heart cytochrome c oxidase at the fully oxidized state 分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... 著者 Tsukihara, T, Shimokata, K, Katayama, Y, Shimada, H, Muramoto, K, Aoyama, H, Mochizuki, M, Shinzawa-Itoh, K, Yamashita, E, Yao, M, Ishimura, Y, Yoshikawa, S. 登録日 2003-11-21 公開日 2003-12-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process. Proc.Natl.Acad.Sci.Usa, 100, 2003
1T7J	crystal structure of inhibitor amprenavir in complex with a multi-drug resistant variant of HIV-1 protease (L63P/V82T/I84V) 分子名称: ACETATE ION, Pol Polyprotein, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER 著者 King, N.M, Prabu-Jeyabalan, M, Nalivaika, E.A, Wigerinck, P.B.T.P, De Bethune, M.-P, Schiffer, C.A. 登録日 2004-05-10 公開日 2005-05-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor J.Med.Chem., 48, 2005
1DKF	CRYSTAL STRUCTURE OF A HETERODIMERIC COMPLEX OF RAR AND RXR LIGAND-BINDING DOMAINS 分子名称: 4-[(4,4-DIMETHYL-1,2,3,4-TETRAHYDRO-[1,2']BINAPTHALENYL-7-CARBONYL)-AMINO]-BENZOIC ACID, OLEIC ACID, PROTEIN (RETINOIC ACID RECEPTOR-ALPHA), ... 著者 Bourguet, W, Vivat, V, Wurtz, J.M, Chambon, P, Gronemeyer, H, Moras, D, Structural Proteomics in Europe (SPINE) 登録日 1999-12-07 公開日 2000-04-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a heterodimeric complex of RAR and RXR ligand-binding domains. Mol.Cell, 5, 2000
2CHN	Bacteroides thetaiotaomicron hexosaminidase with O-GlcNAcase activity- NAG-thiazoline complex 分子名称: 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, CALCIUM ION, GLUCOSAMINIDASE, ... 著者 Dennis, R.J, Taylor, E.J, Macauley, M.S, Stubbs, K.A, Turkenburg, J.P, Hart, S.J, Black, G.N, Vocadlo, D.J, Davies, G.J. 登録日 2006-03-15 公開日 2006-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity Nat.Struct.Mol.Biol., 13, 2006
1Q8A	Cobalamin-dependent methionine synthase (1-566) from Thermotoga maritima (Cd2+:L-Hcy complex, Se-Met) 分子名称: 2-AMINO-4-MERCAPTO-BUTYRIC ACID, 5-methyltetrahydrofolate S-homocysteine methyltransferase, CADMIUM ION 著者 Evans, J.C, Huddler, D.P, Hilgers, M.T, Romanchuk, G, Matthews, R.G, Ludwig, M.L. 登録日 2003-08-20 公開日 2004-03-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase. Proc.Natl.Acad.Sci.Usa, 101, 2004
1TEZ	COMPLEX BETWEEN DNA AND THE DNA PHOTOLYASE FROM ANACYSTIS NIDULANS 分子名称: 5'-D(*AP*TP*CP*GP*GP*CP*T*(TCP)P*CP*GP*C)-3', 5'-D(*TP*CP*GP*C)-3', 5'-D(P*CP*GP*AP*AP*GP*CP*CP*GP*A)-3', ... 著者 Essen, L.-O, Carell, T, Mees, A, Klar, T. 登録日 2004-05-26 公開日 2004-12-14 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a photolyase bound to a CPD-like DNA lesion after in situ repair Science, 306, 2004
1AXO	STRUCTURAL ALIGNMENT OF THE (+)-TRANS-ANTI-[BP]DG ADDUCT POSITIONED OPPOSITE DC AT A DNA TEMPLATE-PRIMER JUNCTION, NMR, 6 STRUCTURES 分子名称: 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA DUPLEX D(AAC-[BP]G-CTACCATCC)D(GGATGGTAGC) 著者 Feng, B, Gorin, A.A, Hingerty, B.E, Geacintov, N.E, Broyde, S, Patel, D.J. 登録日 1997-10-16 公開日 1998-07-01 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural alignment of the (+)-trans-anti-benzo[a]pyrene-dG adduct positioned opposite dC at a DNA template-primer junction. Biochemistry, 36, 1997
2CVD	Crystal structure analysis of human hematopoietic prostaglandin D synthase complexed with HQL-79 分子名称: 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE, GLUTATHIONE, GLYCEROL, ... 著者 Aritake, K, Kado, Y, Inoue, T, Miyano, M, Urade, Y. 登録日 2005-06-02 公開日 2006-04-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structural and Functional Characterization of HQL-79, an Orally Selective Inhibitor of Human Hematopoietic Prostaglandin D Synthase. J.Biol.Chem., 281, 2006
1T4E	Structure of Human MDM2 in complex with a Benzodiazepine Inhibitor 分子名称: (4-CHLOROPHENYL)[3-(4-CHLOROPHENYL)-7-IODO-2,5-DIOXO-1,2,3,5-TETRAHYDRO-4H-1,4-BENZODIAZEPIN-4-YL]ACETIC ACID, Ubiquitin-protein ligase E3 Mdm2 著者 Grasberger, B.L, Schubert, C, Koblish, H.K, Carver, T.E, Franks, C.F, Zhao, S.Y, Lu, T, LaFrance, L.V, Parks, D.J. 登録日 2004-04-29 公開日 2005-02-08 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells J.Med.Chem., 48, 2005
2EXA	Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, complexed with FAROM 分子名称: (2R,5R)-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-5-[(2R)-tetrahydrofuran-2-yl]-2,5-dihydro-1,3-thiazole-4-carboxylic acid, GLYCEROL, Penicillin-binding protein 4 著者 Kishida, H, Unzai, S, Roper, D.I, Lloyd, A, Park, S.-Y, Tame, J.R.H. 登録日 2005-11-08 公開日 2006-06-13 最終更新日 2016-10-19 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of penicillin binding protein 4 (dacB) from Escherichia coli, both in the native form and covalently linked to various antibiotics Biochemistry, 45, 2006
2F3F	Crystal Structure of the Bace complex with BDF488, a macrocyclic inhibitor 分子名称: (2R,4S)-N-BUTYL-4-HYDROXY-2-METHYL- 4-((E)-(4AS,12R,15S,17AS)-15-METHYL -14,17-DIOXO-2,3,4,4A,6,9,11,12,13, 14,15,16,17,17A-TETRADECAHYDRO-1H-5 ,10-DITHIA-1,13,16-TRIAZA-BENZOCYCL OPENTADECEN-12-YL)-BUTYRAMIDE, Beta-secretase 1 著者 Rondeau, J.-M. 登録日 2005-11-21 公開日 2006-09-05 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). J.Med.Chem., 49, 2006
2CB8	High resolution crystal structure of liganded human L-ACBP 分子名称: 2-METHOXYETHANOL, ACYL-COA-BINDING PROTEIN, SULFATE ION, ... 著者 Taskinen, J.P, van Aalten, D.M, Knudsen, J, Wierenga, R.K. 登録日 2006-01-03 公開日 2006-10-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 High Resolution Crystal Structures of Unliganded and Liganded Human Liver Acbp Reveal a New Mode of Binding for the Acyl-Coa Ligand. Proteins: Struct., Funct., Bioinf., 66, 2007
1U2Y	In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing D-gluconhydroximo-1,5-lactam 分子名称: (2S,3S,4R,5R)-6-(HYDROXYAMINO)-2-(HYDROXYMETHYL)-2,3,4,5-TETRAHYDROPYRIDINE-3,4,5-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-amylase, ... 著者 Numao, S, Li, C, Damager, I, Wrodnigg, T.M, Begum, A, Overall, C.M, Brayer, G.D, Withers, S.G. 登録日 2004-07-20 公開日 2004-09-07 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors. J.Biol.Chem., 279, 2004
2HUB	Structure of Hen Egg-White Lysozyme Determined from crystals grown in pH 7.5 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D(-)-TARTARIC ACID, ... 著者 Frolow, F, Lagziel-Simis, S, Cohen-Hadar, N, Wine, Y, Freeman, A. 登録日 2006-07-26 公開日 2007-07-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.201 Å) 主引用文献 Monitoring influence of pH on the molecular and crystal structure of hen egg-white tetragonal lysozyme To be Published
1UUX	Structure of a molybdopterin-bound cnx1g domain links molybdenum and copper metabolism 分子名称: COPPER (I) ION, FORMIC ACID, IMIDAZOLE, ... 著者 Kuper, J, Llamas, A, Hecht, H.J, Mendel, R.R, Schwarz, G. 登録日 2004-01-12 公開日 2004-08-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of a Molybdopterin-Bound Cnx1G Domain Links Molybdenum and Copper Metabolism Nature, 430, 2004
1UPD	Oxidized STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 分子名称: CYTOCHROME C3, HEME C 著者 Bento, I, Matias, P.M, Baptista, A.M, Da Costa, P.N, Van Dongen, W.M.A.M, Saraiva, L.M, Schneider, T.R, Soares, C.M, Carrondo, M.A. 登録日 2003-09-29 公開日 2004-09-30 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6 Proteins, 54, 2004
1UUY	Structure of a molybdopterin-bound cnx1g domain links molybdenum and copper metabolism 分子名称: ADENOSINE MONOPHOSPHATE, COPPER (I) ION, FORMIC ACID, ... 著者 Kuper, J, Llamas, A, Hecht, H.J, Mendel, R.R, Schwarz, G. 登録日 2004-01-12 公開日 2004-08-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Structure of a Molybdopterin-Bound Cnx1G Domain Links Molybdenum and Copper Metabolism Nature, 430, 2004
2A6U	pH evolution of tetragonal HEWL at 4 degrees Celcius. 分子名称: Lysozyme C 著者 Margiolaki, I. 登録日 2005-07-04 公開日 2006-01-03 最終更新日 2018-04-25 実験手法 POWDER DIFFRACTION 主引用文献 High-throughput phase-diagram mapping via powder diffraction: a case study of HEWL versus pH. Acta Crystallogr.,Sect.D, 61, 2005
1UP9	REDUCED STRUCTURE OF CYTOCHROME C3 FROM DESULFOVIBRIO DESULFURICANS ATCC 27774 AT PH 7.6 分子名称: CYTOCHROME C3, HEME C, SULFATE ION 著者 Bento, I, Matias, P.M, Baptista, A.M, Da Costa, P.N, Van Dongen, W.M.A.M, Saraiva, L.M, Schneider, T.R, Soares, C.M, Carrondo, M.A. 登録日 2003-09-29 公開日 2004-09-30 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Molecular Basis for Redox-Bohr and Cooperative Effects in Cytochrome C3 from Desulfovibrio Desulfuricans Atcc 27774: Crystallographic and Modeling Studies of Oxidized and Reduced High-Resolution Structures at Ph 7.6 Proteins, 54, 2004
1DSA	(+)-DUOCARMYCIN SA COVALENTLY LINKED TO DUPLEX DNA, NMR, 20 STRUCTURES 分子名称: 4-HYDROXY-8-METHYL-6-(4,5,6-TRIMETHOXY-1H-INDOLE-2-CARBONYL)-3,6,7,8-TETRAHYDRO-3,6-DIAZA-AS-INDACENE-2-CARBOXYLIC ACID METHYL ESTER, DNA (5'-D(*GP*AP*CP*TP*AP*AP*TP*TP*GP*AP*C)-3', 5'-D(*GP*TP*CP*AP*AP*TP*TP*AP*GP*TP*C)-3') 著者 Eis, P.S, Smith, J.A, Case, D.A, Chazin, W.J. 登録日 1997-05-08 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 High resolution solution structure of a DNA duplex alkylated by the antitumor agent duocarmycin SA. J.Mol.Biol., 272, 1997
1DSI	Solution structure of a duocarmycin sa-indole-alkylated dna dupleX 分子名称: 4-HYDROXY-6-(1H-INDOLE-2-CARBONYL)-8-METHYL-3,6,7,8-TETRAHYDRO-3,6-DIAZA-AS-INDACENE-2-CARBOXYLIC ACID METHYL ESTER, DNA (5'-D(*GP*AP*CP*TP*AP*AP*TP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*AP*TP*TP*AP*GP*TP*C)-3') 著者 Schnell, J.R, Ketchem, R.R, Boger, D.L, Chazin, W.J. 登録日 1998-07-29 公開日 1998-08-05 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Binding-Induced Activation of DNA Alkylation by Duocarmycin SA: Insights from the Structure of an Indole Derivative-DNA Adduct J.Am.Chem.Soc., 121, 1999

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