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1U2Y

In situ extension as an approach for identifying novel alpha-amylase inhibitors, structure containing D-gluconhydroximo-1,5-lactam

Summary for 1U2Y
Entry DOI10.2210/pdb1u2y/pdb
Related1CPU 1U30 1U33
DescriptorAlpha-amylase, pancreatic, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (6 entities in total)
Functional Keywordsglycosidase, human pancreatic alpha-amylase, acarbose, inhibitor, glucosidase, enzyme mechanism, hydrolase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight56420.21
Authors
Numao, S.,Li, C.,Damager, I.,Wrodnigg, T.M.,Begum, A.,Overall, C.M.,Brayer, G.D.,Withers, S.G. (deposition date: 2004-07-20, release date: 2004-09-07, Last modification date: 2020-07-29)
Primary citationNumao, S.,Damager, I.,Li, C.,Wrodnigg, T.M.,Begum, A.,Overall, C.M.,Brayer, G.D.,Withers, S.G.
In Situ Extension as an Approach for Identifying Novel alpha-Amylase Inhibitors.
J.Biol.Chem., 279:48282-48291, 2004
Cited by
PubMed: 15304511
DOI: 10.1074/jbc.M406804200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

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