PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

---

6NR9	hTRiC-hPFD Class5 分子名称: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... 著者 Gestaut, D, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. 登録日 2019-01-23 公開日 2019-06-19 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (8.5 Å) 主引用文献 The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
6NRD	hTRiC-hPFD Class4 分子名称: Prefoldin subunit 1, Prefoldin subunit 2, Prefoldin subunit 3, ... 著者 Gestaut, D.R, Roh, S.H, Ma, B, Pintilie, G, Joachimiak, L.A, Leitner, A, Walzthoeni, T, Aebersold, R, Chiu, W, Frydman, J. 登録日 2019-01-23 公開日 2019-06-19 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (8.2 Å) 主引用文献 The Chaperonin TRiC/CCT Associates with Prefoldin through a Conserved Electrostatic Interface Essential for Cellular Proteostasis. Cell, 177, 2019
6NU5	Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine 分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYSTEINE, ... 著者 Srivastava, D, Nandi, S, Dey, M. 登録日 2019-01-30 公開日 2019-08-21 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2. Biochemistry, 58, 2019
3NSY	The multi-copper oxidase CueO with six Met to Ser mutations (M358S,M361S,M362S,M364S,M366S,M368S) 分子名称: Blue copper oxidase cueO, COPPER (II) ION, CU-O-CU LINKAGE 著者 Roberts, S.A, Montfort, W.R, Singh, S.K. 登録日 2010-07-02 公開日 2011-08-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of multicopper oxidase CueO bound to copper(I) and silver(I): functional role of a methionine-rich sequence. J. Biol. Chem., 286, 2011
5OOB	COMPLEX OF HUMAN NUCLEAR CAP-BINDING COMPLEX WITH M7GTP AND NELF-E C-TERMINAL PEPTIDE 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Negative elongation factor E, Nuclear cap-binding protein subunit 1, ... 著者 Cusack, S, Schulze, W.M. 登録日 2017-08-07 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2. Nat Commun, 8, 2017
5OO6	Complex of human nuclear cap-binding complex with ARS2 C-terminal peptide 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... 著者 Cusack, S, Schulze, W.M. 登録日 2017-08-06 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for mutually exclusive co-transcriptional nuclear cap-binding complexes with either NELF-E or ARS2. Nat Commun, 8, 2017
6O09	Structure of AtPCNA in complex with the PIP motif of ATXR6 分子名称: Proliferating cellular nuclear antigen 1, Uncharacterized protein 著者 Couture, J.F, Davarinejad, H. 登録日 2019-02-15 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 ATXR5/6 Forms Alternative Protein Complexes with PCNA and the Nucleosome Core Particle. J. Mol. Biol., 431, 2019
4HAL	Multicopper Oxidase CueO mutant E506I 分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION, ... 著者 Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y. 登録日 2012-09-26 公開日 2013-10-30 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Multicopper Oxidase CueO mutant E506I TO BE PUBLISHED
3UAC	Multicopper Oxidase CueO mutant C500SE506Q (data4) 分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION, ... 著者 Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y. 登録日 2011-10-21 公開日 2012-04-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 An O-centered structure of the trinuclear copper center in the Cys500Ser/Glu506Gln mutant of CueO and structural changes in low to high X-ray dose conditions. Angew.Chem.Int.Ed.Engl., 51, 2012
5OR8	Crystal Structure of BAZ2A bromodomain in complex with 1,3-dimethyl-benzimidazolone compound 1 分子名称: Bromodomain adjacent to zinc finger domain protein 2A, ~{N}-[(4-fluorophenyl)methyl]-1,3,6-trimethyl-2-oxidanylidene-benzimidazole-5-sulfonamide 著者 Lolli, G, Dalle Vedove, A, Marchand, J.-R, Caflisch, A. 登録日 2017-08-15 公開日 2017-09-13 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking. J Chem Inf Model, 57, 2017
3T3Z	Human Cytochrome P450 2E1 in complex with pilocarpine 分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Meneely, K.M, DeVore, N.M, Scott, E.E. 登録日 2011-07-25 公開日 2011-12-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
3PAV	The reduced form of CueO 分子名称: Blue copper oxidase cueO, COPPER (II) ION 著者 Montfort, W.R, Roberts, S.A, Singh, S.K. 登録日 2010-10-19 公開日 2011-10-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The reduced form of CueO To be Published
3UAA	Multicopper Oxidase CueO mutant C500SE506Q (data1) 分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION, ... 著者 Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y. 登録日 2011-10-21 公開日 2012-04-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 An O-centered structure of the trinuclear copper center in the Cys500Ser/Glu506Gln mutant of CueO and structural changes in low to high X-ray dose conditions. Angew.Chem.Int.Ed.Engl., 51, 2012
3UAE	Multicopper Oxidase CueO mutant C500SE506Q (data6) 分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION, ... 著者 Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y. 登録日 2011-10-21 公開日 2012-04-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 An O-centered structure of the trinuclear copper center in the Cys500Ser/Glu506Gln mutant of CueO and structural changes in low to high X-ray dose conditions. Angew.Chem.Int.Ed.Engl., 51, 2012
3PAU	CueO in the resting oxidized state 分子名称: Blue copper oxidase cueO, COPPER (II) ION, CU-O-CU LINKAGE 著者 Roberts, S.A, Singh, S, Montfort, W.R. 登録日 2010-10-19 公開日 2011-10-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 CueO in the resting oxidized state To be Published
4HAK	Multicopper Oxidase CueO mutant E506A 分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION, ... 著者 Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y. 登録日 2012-09-26 公開日 2013-10-30 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Multicopper Oxidase CueO mutant E506A TO BE PUBLISHED
3UAD	Multicopper Oxidase CueO mutant C500SE506Q (data5) 分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION, ... 著者 Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y. 登録日 2011-10-21 公開日 2012-04-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 An O-centered structure of the trinuclear copper center in the Cys500Ser/Glu506Gln mutant of CueO and structural changes in low to high X-ray dose conditions. Angew.Chem.Int.Ed.Engl., 51, 2012
3UAB	Multicopper Oxidase CueO mutant C500SE506Q (data2) 分子名称: ACETATE ION, Blue copper oxidase CueO, COPPER (II) ION, ... 著者 Komori, H, Kataoka, K, Sakurai, T, Higuchi, Y. 登録日 2011-10-21 公開日 2012-04-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 An O-centered structure of the trinuclear copper center in the Cys500Ser/Glu506Gln mutant of CueO and structural changes in low to high X-ray dose conditions. Angew.Chem.Int.Ed.Engl., 51, 2012
9BF0	MID domain of human Argo2 bound to UTP 分子名称: Protein argonaute-2, URIDINE 5'-TRIPHOSPHATE 著者 Harp, J.M, Egli, M. 登録日 2024-04-16 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
9BF2	MID domain of Ago2 bound to UMP 分子名称: Protein argonaute-2, URIDINE-5'-MONOPHOSPHATE 著者 Harp, J.M, Egli, M. 登録日 2024-04-16 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
8BV1	Peptide inhibitor P4 in complex with ASF1 histone chaperone 分子名称: GLYCEROL, Histone chaperone ASF1A, P4 peptide inhibitor of histone chaperone ASF1 著者 Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. 登録日 2022-12-01 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.834 Å) 主引用文献 Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
6TTI	PKM2 in complex with Compound 6 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, DIMETHYL SULFOXIDE, Pyruvate kinase PKM, ... 著者 Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A. 登録日 2019-12-27 公開日 2020-01-15 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.5 Å) 主引用文献 Fragment-based drug discovery using cryo-EM. Drug Discov Today, 25, 2020
6TKR	Tankyrase 2 in complex with an inhibitor (OM-1704) 分子名称: Tankyrase-2, ZINC ION, ~{N}-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]-1,5-naphthyridine-2-carboxamide 著者 Sowa, S.T, Lehtio, L. 登録日 2019-11-28 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Preclinical Lead Optimization of a 1,2,4-Triazole Based Tankyrase Inhibitor. J.Med.Chem., 63, 2020
5R8J	PanDDA analysis group deposition INTERLEUKIN-1 BETA -- Fragment Z355728146 in complex with INTERLEUKIN-1 BETA 分子名称: 2-[(2~{R},5~{S})-2,5-dimethylmorpholin-4-yl]-~{N}-ethyl-ethanamide, Interleukin-1 beta, SULFATE ION 著者 De Nicola, G.F, Nichols, C.E. 登録日 2020-03-03 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020
5R8Z	PanDDA analysis group deposition Form1 MAP kinase p38-alpha -- Fragment N01381c in complex with MAP kinase p38-alpha 分子名称: 6-methoxypyridine-3-carbothioamide, ACETATE ION, CHLORIDE ION, ... 著者 De Nicola, G.F, Nichols, C.E. 登録日 2020-03-04 公開日 2020-07-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1 beta-IL1R and p38 alpha-TAB1 Complexes. J.Med.Chem., 63, 2020

<551552553554555556557558559560561562563564565566>