PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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5ND4	Microtubule-bound MKLP2 motor domain in the presence of ADP.AlFx 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J, Yu, I.-M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. 登録日 2017-03-07 公開日 2017-10-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
5ND2	Microtubule-bound MKLP2 motor domain in the presence of ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Atherton, J, Yu, I.M, Cook, A, Muretta, J.M, Joseph, A.P, Major, J, Sourigues, Y, Clause, J, Topf, M, Rosenfeld, S.S, Houdusse, A, Moores, C.A. 登録日 2017-03-07 公開日 2017-10-04 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry. Elife, 6, 2017
5NP0	Closed dimer of human ATM (Ataxia telangiectasia mutated) 分子名称: Serine-protein kinase ATM 著者 Baretic, D, Pollard, H.K, Fisher, D.I, Johnson, C.M, Santhanam, B, Truman, C.M, Kouba, T, Fersht, A.R, Phillips, C, Williams, R.L. 登録日 2017-04-13 公開日 2017-05-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of closed and open conformations of dimeric human ATM. Sci Adv, 3, 2017
6N7U	apo-BDBV223 Fab 分子名称: BDBV223 antibody heavy chain, BDBV223 antibody light chain 著者 King, L.B, West, B.R, Saphire, E.O. 登録日 2018-11-28 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun, 10, 2019
7T58	Crystal structure of Miz1 BTB domain 分子名称: DIMETHYL SULFOXIDE, Zinc finger and BTB domain-containing protein 17 著者 Linhares, B.M, Cierpicki, T. 登録日 2021-12-11 公開日 2022-12-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.05333114 Å) 主引用文献 Prediction of BTB domain ligandability guided by protein dynamics To Be Published
6N3D	Structure of HIV Tat-specific factor 1 U2AF Homology Motif (APO-State) 分子名称: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Loerch, S, Jenkins, J.L, Kielkopf, C.L. 登録日 2018-11-15 公開日 2019-01-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
6N3Y	Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[(3-Indolyl)-1-Ethyl]Carbamoyl Guanosine 分子名称: 5'-O-{[2-(1H-indol-3-yl)ethyl]carbamoyl}guanosine, CHLORIDE ION, Histidine triad nucleotide-binding protein 1 著者 Strom, A.M, Finzel, B.C. 登録日 2018-11-16 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chem Neurosci, 10, 2019
7Q33	Solution structure of RBM39 RRM2 bound to 5'-AGCUUUG-3 分子名称: RNA (5'-R(*AP*GP*CP*UP*UP*UP*G)-3'), RNA-binding protein 39 著者 Campagne, S, Allain, F.H. 登録日 2021-10-26 公開日 2023-02-08 最終更新日 2023-09-20 実験手法 SOLUTION NMR 主引用文献 Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39. Nat Commun, 14, 2023
8GNN	Crystal structure of the human RAD9-RAD1-HUS1-RAD17 complex 分子名称: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1, Cell cycle checkpoint protein RAD17, ... 著者 Hara, K, Nagata, K, Iida, N, Hashimoto, H. 登録日 2022-08-24 公開日 2023-03-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.119 Å) 主引用文献 The 9-1-1 DNA clamp subunit RAD1 forms specific interactions with clamp loader RAD17, revealing functional implications for binding-protein RHINO. J.Biol.Chem., 299, 2023
8FL4	Human nuclear pre-60S ribosomal subunit (State I3) 分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ... 著者 Vanden Broeck, A, Klinge, S. 登録日 2022-12-21 公開日 2023-07-12 最終更新日 2023-07-19 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Principles of human pre-60 S biogenesis. Science, 381, 2023
8FCO	Cryo-EM structure of p97:UBXD1 meta state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 著者 Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. 登録日 2022-12-01 公開日 2023-06-21 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.31 Å) 主引用文献 The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
8GRM	Cryo-EM structure of PRC1 bound to H2AK119-UbcH5b-Ub nucleosome 分子名称: COMMD3 protein, DNA (144-MER), DNA (145-MER), ... 著者 Ai, H.S, Zebin, T, Zhihend, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L. 登録日 2022-09-02 公開日 2023-04-12 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (3.05 Å) 主引用文献 Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination. Chem, 2023
8FCL	Cryo-EM structure of p97:UBXD1 closed state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 著者 Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. 登録日 2022-12-01 公開日 2023-06-21 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.51 Å) 主引用文献 The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
8FCR	Cryo-EM structure of p97:UBXD1 H4-bound state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 著者 Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. 登録日 2022-12-01 公開日 2023-06-21 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (4.12 Å) 主引用文献 The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
5NWG	Crystal structure of TNKS2 in complex with 7-chloro-2-{4-[(2-hydroxyethyl)(methyl)amino]phenyl}-3,4-dihydroquinazolin-4-one 分子名称: 7-chloranyl-2-[4-[2-hydroxyethyl(methyl)amino]phenyl]-3~{H}-quinazolin-4-one, GLYCEROL, SULFATE ION, ... 著者 Nkizinkiko, Y, Haikarainen, T, Lehtio, L. 登録日 2017-05-05 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 2-Phenylquinazolinones as dual-activity tankyrase-kinase inhibitors. Sci Rep, 8, 2018
8FCQ	Cryo-EM structure of p97:UBXD1 PUB-in state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 著者 Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. 登録日 2022-12-01 公開日 2023-06-21 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.93 Å) 主引用文献 The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
6N45	Crystal structure of the cryptic polo box domain of human activated Plk4 variant 1 分子名称: Chimera protein of Serine/threonine-protein kinase PLK4 and DDB1- and CUL4-associated factor 1 著者 Zhang, L, Park, J.-E, Meng, L, Lee, K.S. 登録日 2018-11-17 公開日 2019-09-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.64 Å) 主引用文献 Phase separation of Polo-like kinase 4 by autoactivation and clustering drives centriole biogenesis. Nat Commun, 10, 2019
7SUK	Structure of Bfr2-Lcp5 Complex Observed in the Small Subunit Processome Isolated from R2TP-depleted Yeast Cells 分子名称: 18S pre-rRNA, 40S ribosomal protein S11-A, 40S ribosomal protein S13, ... 著者 Rai, J, Zhao, Y, Li, H. 登録日 2021-11-17 公開日 2022-07-06 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Artificial intelligence-assisted cryoEM structure of Bfr2-Lcp5 complex observed in the yeast small subunit processome. Commun Biol, 5, 2022
8FCM	Cryo-EM structure of p97:UBXD1 open state 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 6 著者 Braxton, J.R, Tucker, M.R, Tse, E, Southworth, D.R. 登録日 2022-12-01 公開日 2023-06-21 最終更新日 2023-12-20 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 The p97/VCP adaptor UBXD1 drives AAA+ remodeling and ring opening through multi-domain tethered interactions. Nat.Struct.Mol.Biol., 30, 2023
6N3V	Human Histidine Triad Nucleotide Binding Protein 1 (Hint1) with Bound 5'-O-[1-Ethyl]Carbamoyl Guanosine 分子名称: 5'-O-(ethylcarbamoyl)guanosine, CHLORIDE ION, Histidine triad nucleotide-binding protein 1 著者 Strom, A.M, Finzel, B.C. 登録日 2018-11-16 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Inhibition of HINT1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chem Neurosci, 10, 2019
6N3E	Structure of HIV Tat-specific factor 1 U2AF Homology Motif bound to U2AF ligand motif 4 分子名称: FORMIC ACID, GLYCEROL, HIV Tat-specific factor 1, ... 著者 Loerch, S, Jenkins, J.L, Kielkopf, C.L. 登録日 2018-11-15 公開日 2019-01-02 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.893 Å) 主引用文献 The pre-mRNA splicing and transcription factor Tat-SF1 is a functional partner of the spliceosome SF3b1 subunit via a U2AF homology motif interface. J. Biol. Chem., 294, 2019
6N7J	BDBV223 Fab bound to synthetic peptide of Bundibugyo virus Glycoprotein Stalk 分子名称: BDBV223 antibody heavy chain, BDBV223 antibody light chain, Envelope glycoprotein 著者 King, L.B, West, B.R, Saphire, E.O. 登録日 2018-11-27 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.684 Å) 主引用文献 Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun, 10, 2019
8GAO	bacteriophage T4 stalled primosome with mutant gp41-E227Q 分子名称: DNA (70-mer), DNA primase, DnaB-like replicative helicase, ... 著者 Feng, X, Li, H. 登録日 2023-02-23 公開日 2023-06-07 最終更新日 2023-08-23 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural basis of the T4 bacteriophage primosome assembly and primer synthesis. Nat Commun, 14, 2023
2YXW	The deletion mutant of Multicopper Oxidase CueO 分子名称: Blue copper oxidase cueO, COPPER (II) ION, CU-O-CU LINKAGE, ... 著者 Higuchi, Y, Komori, H. 登録日 2007-04-27 公開日 2008-01-01 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure and function of the engineered multicopper oxidase CueO from Escherichia coli--deletion of the methionine-rich helical region covering the substrate-binding site J.Mol.Biol., 373, 2007
7U46	Cryo-EM structure of CENP-A nucleosome (palindromic alpha satellite DNA) in complex with CENP-N 分子名称: Centromere protein N, DNA (147-MER), Histone H2A, ... 著者 Zhou, K, Luger, K. 登録日 2022-02-28 公開日 2022-03-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.68 Å) 主引用文献 CENP-N promotes the compaction of centromeric chromatin. Nat.Struct.Mol.Biol., 29, 2022

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