7DHZ
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8HHL
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![BU of 8hhl by Molmil](/molmil-images/mine/8hhl) | Cryo-EM structure of the Cas12m2-crRNA-target DNA full R-loop complex | 分子名称: | Cas12m2, MAGNESIUM ION, NTS (36-MER), ... | 著者 | Omura, N.S, Nakagawa, R, Wu, Y.W, Sudfeld, C, Warren, V.R, Hirano, H, Kusakizako, T, Kise, Y, Lebbink, H.G.J, Itoh, Y, Oost, V.D.J, Nureki, O. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-08-30 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme. Nat.Struct.Mol.Biol., 30, 2023
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6KW4
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![BU of 6kw4 by Molmil](/molmil-images/mine/6kw4) | The ClassB RSC-Nucleosome Complex | 分子名称: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | 著者 | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | 登録日 | 2019-09-06 | 公開日 | 2019-11-13 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (7.55 Å) | 主引用文献 | Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
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8SOJ
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4V9C
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![BU of 4v9c by Molmil](/molmil-images/mine/4v9c) | Allosteric control of the ribosome by small-molecule antibiotics | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Cate, J.H.D, Pulk, A, Blanchard, S.C, Wang, L, Feldman, M.B, Wasserman, M.R, Altman, R. | 登録日 | 2012-07-25 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Allosteric control of the ribosome by small-molecule antibiotics. Nat.Struct.Mol.Biol., 19, 2012
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7R5V
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![BU of 7r5v by Molmil](/molmil-images/mine/7r5v) | Structure of the human CCAN CENP-A alpha-satellite complex | 分子名称: | Centromere protein H, Centromere protein I, Centromere protein K, ... | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | 登録日 | 2022-02-11 | 公開日 | 2022-04-27 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.55 Å) | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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8BQ2
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![BU of 8bq2 by Molmil](/molmil-images/mine/8bq2) | CryoEM structure of the pre-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ... | 著者 | Appleby, R, Bollschweiler, D, Pellegrini, L. | 登録日 | 2022-11-18 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly. Iscience, 26, 2023
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8BR2
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![BU of 8br2 by Molmil](/molmil-images/mine/8br2) | CryoEM structure of the post-synaptic RAD51 nucleoprotein filament in the presence of ATP and Ca2+ | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*GP*CP*GP*AP*GP*CP*TP*CP*GP*AP*TP*GP*CP*AP*CP*CP*TP*CP*CP*A)-3'), ... | 著者 | Appleby, R, Bollschweiler, D, Pellegrini, L. | 登録日 | 2022-11-22 | 公開日 | 2023-05-03 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | A metal ion-dependent mechanism of RAD51 nucleoprotein filament disassembly. Iscience, 26, 2023
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7R5R
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![BU of 7r5r by Molmil](/molmil-images/mine/7r5r) | Structure of the human CCAN CENP-A alpha-satellite complex | 分子名称: | Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ... | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | 登録日 | 2022-02-11 | 公開日 | 2022-04-27 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.44 Å) | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
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2XE0
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![BU of 2xe0 by Molmil](/molmil-images/mine/2xe0) | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus | 分子名称: | 24MER DNA, ACETATE ION, I-CREI V2V3 VARIANT, ... | 著者 | Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Redondo, P, Villate, M, Merino, N, Marenchino, M, D'Abramo, M, Gervasio, F.L, Grizot, S, Daboussi, F, Smith, J, Chion-Sotine, I, Paques, F, Duchateau, P, Alibes, A, Stricher, F, Serrano, L, Blanco, F.J, Montoya, G. | 登録日 | 2010-05-10 | 公開日 | 2010-09-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Molecular Basis of Engineered Meganuclease Targeting of the Endogenous Human Rag1 Locus Nucleic Acids Res., 39, 2011
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6R64
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![BU of 6r64 by Molmil](/molmil-images/mine/6r64) | N-terminal domain of modification dependent EcoKMcrA restriction endonuclease (NEco) in complex with C5mCGG target sequence | 分子名称: | 5-methylcytosine-specific restriction enzyme A, DNA (5'-D(*GP*AP*AP*CP*(5CM)P*GP*GP*TP*GP*A)-3'), DNA (5'-D(*TP*CP*AP*CP*(5CM)P*GP*GP*TP*TP*C)-3') | 著者 | Slyvka, A, Zagorskaite, E, Czapinska, H, Sasnauskas, G, Bochtler, M. | 登録日 | 2019-03-26 | 公開日 | 2019-10-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Crystal structure of the EcoKMcrA N-terminal domain (NEco): recognition of modified cytosine bases without flipping. Nucleic Acids Res., 47, 2019
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8S94
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8S91
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8SPO
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![BU of 8spo by Molmil](/molmil-images/mine/8spo) | Tetramerized activation of MapSPARTA bound with NAD+ | 分子名称: | MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Piwi domain-containing protein, ... | 著者 | Shen, Z.F, Yang, X.Y, Fu, T.M. | 登録日 | 2023-05-03 | 公開日 | 2023-08-23 | 最終更新日 | 2023-09-20 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Oligomerization-mediated activation of a short prokaryotic Argonaute. Nature, 621, 2023
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6X59
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![BU of 6x59 by Molmil](/molmil-images/mine/6x59) | The mouse cGAS catalytic domain binding to human assembled nucleosome | 分子名称: | Cyclic GMP-AMP synthase, DNA, Histone H2A type 1, ... | 著者 | Pengbiao, X, Pingwei, L, Baoyu, Z. | 登録日 | 2020-05-25 | 公開日 | 2020-09-16 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | The molecular basis of tight nuclear tethering and inactivation of cGAS. Nature, 587, 2020
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8HAL
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![BU of 8hal by Molmil](/molmil-images/mine/8hal) | Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 1 | 分子名称: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAM
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![BU of 8ham by Molmil](/molmil-images/mine/8ham) | Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 2 | 分子名称: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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8HAN
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![BU of 8han by Molmil](/molmil-images/mine/8han) | Cryo-EM structure of the CBP catalytic core bound to the H4K12acK16ac nucleosome, class 3 | 分子名称: | CREB-binding protein, DNA (180-mer), Histone H2A type 1-B/E, ... | 著者 | Kikuchi, M, Morita, S, Wakamori, M, Shin, S, Uchikubo-Kamo, T, Shirouzu, M, Umehara, T. | 登録日 | 2022-10-26 | 公開日 | 2023-05-17 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Epigenetic mechanisms to propagate histone acetylation by p300/CBP. Nat Commun, 14, 2023
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2FU4
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![BU of 2fu4 by Molmil](/molmil-images/mine/2fu4) | Crystal Structure of the DNA binding domain of E.coli FUR (Ferric Uptake Regulator) | 分子名称: | CADMIUM ION, CHLORIDE ION, Ferric uptake regulation protein, ... | 著者 | Pecqueur, L, D'Autreaux, B, Dupuy, J, Nicolet, Y, Jacquamet, L, Brutscher, B, Michaud-Soret, I, Bersch, B. | 登録日 | 2006-01-26 | 公開日 | 2006-05-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural changes of Escherichia coli ferric uptake regulator during metal-dependent dimerization and activation explored by NMR and X-ray crystallography J.Biol.Chem., 281, 2006
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3KZ9
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![BU of 3kz9 by Molmil](/molmil-images/mine/3kz9) | Crystal structure of the master transcriptional regulator, SmcR, in Vibrio vulnificus provides insight into its DNA recognition mechanism | 分子名称: | SULFATE ION, SmcR | 著者 | Kim, M.H, Kim, Y, Choi, W.-C, Hwang, J. | 登録日 | 2009-12-08 | 公開日 | 2010-03-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The crystal structure of SmcR, a quorum-sensing master regulator of Vibrio vulnificus, provides insight into its regulation of transcription J.Biol.Chem., 285, 2010
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4UUS
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![BU of 4uus by Molmil](/molmil-images/mine/4uus) | CRYSTAL STRUCTURE OF A UBX-EXD-DNA COMPLEX INCLUDING THE UBDA MOTIF | 分子名称: | 5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3', 5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3', HOMEOTIC PROTEIN EXTRADENTICLE, ... | 著者 | Foos, N, Mate, M.J, Ortiz-Lombardia, M. | 登録日 | 2014-07-31 | 公開日 | 2015-02-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/Pbc Interaction Mode. Structure, 23, 2015
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6L9Z
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![BU of 6l9z by Molmil](/molmil-images/mine/6l9z) | 338 bp di-nucleosome assembled with linker histone H1.X | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (338-MER), ... | 著者 | Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A. | 登録日 | 2019-11-11 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Engineering nucleosomes for generating diverse chromatin assemblies. Nucleic Acids Res., 49, 2021
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8GAM
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![BU of 8gam by Molmil](/molmil-images/mine/8gam) | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | 分子名称: | Cas11, Cas5, Cas7, ... | 著者 | Hu, C, Nam, K.H, Ke, A. | 登録日 | 2023-02-23 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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3KXB
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6L25
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