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2J49
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Crystal structure of yeast TAF5 N-terminal domain
分子名称: TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5
著者Romier, C, James, N, Birck, C, Cavarelli, J, Vivares, C, Collart, M.A, Moras, D.
登録日2006-08-28
公開日2007-04-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure, Biochemical and Genetic Characterization of Yeast and E. Cuniculi Taf(II)5 N-Terminal Domain: Implications for TFIID Assembly.
J.Mol.Biol., 368, 2007
2J0V
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The crystal structure of Arabidopsis thaliana RAC7-ROP9: the first RAS superfamily GTPase from the plant kingdom
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAC-LIKE GTP-BINDING PROTEIN ARAC7
著者Sormo, C.G, Leiros, I, Brembu, T, Winge, P, Os, V, Bones, A.M.
登録日2006-08-07
公開日2006-10-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献The Crystal Structure of Arabidopsis Thaliana Rac7/Rop9: The First Ras Superfamily Gtpase from the Plant Kingdom.
Phytochemistry, 67, 2006
2J4B
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Crystal structure of Encephalitozoon cuniculi TAF5 N-terminal domain
分子名称: TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 72/90-100 KDA
著者Romier, C, James, N, Birck, C, Cavarelli, J, Vivares, C, Collart, M.A, Moras, D.
登録日2006-08-28
公開日2007-04-10
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure, Biochemical and Genetic Characterization of Yeast and E. Cuniculi Taf(II)5 N-Terminal Domain: Implications for TFIID Assembly.
J.Mol.Biol., 368, 2007
7YVC
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Aplysia californica FaNaC in apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S.
登録日2022-08-19
公開日2023-08-09
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Nat.Chem.Biol., 19, 2023
7YVB
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Aplysia californica FaNaC in ligand bound state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide-gated Na+ channel, ...
著者Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S.
登録日2022-08-19
公開日2023-08-09
最終更新日2023-10-11
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Nat.Chem.Biol., 19, 2023
7YSJ
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GluK1-1a in nanodisc captured in SYM2081 bound desensitized state
分子名称: Glutamate receptor
著者Dhingra, S, Kumar, J.
登録日2022-08-12
公開日2023-08-16
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (5.2 Å)
主引用文献Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors
Elife, 2023
8B0H
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2C9, C5b9-CD59 cryoEM structure
分子名称: CD59 glycoprotein, Complement C5, Complement component C6, ...
著者Couves, E.C, Gardner, S, Bubeck, D.
登録日2022-09-07
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for membrane attack complex inhibition by CD59.
Nat Commun, 14, 2023
8A8K
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PAP phosphatase from Methanothermococcus thermolithotrophicus refined to 3.1 A
分子名称: ADENOSINE MONOPHOSPHATE, GLYCEROL, MANGANESE (II) ION, ...
著者Jespersen, M, Wagner, T.
登録日2022-06-23
公開日2023-04-26
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Assimilatory sulfate reduction in the marine methanogen Methanothermococcus thermolithotrophicus.
Nat Microbiol, 8, 2023
8AW0
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Crystal structure of PksD, the trans-acting acyl hydrolase domain from the bacillaene trans-AT PKS (native)
分子名称: Polyketide biosynthesis acyltransferase homolog PksD, ZINC ION
著者Fage, C.D, Challis, G.L, Lewandowski, J, Jenner, M.
登録日2022-08-28
公開日2023-08-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for acyl hydrolysis in trans-AT polyketide synthases
To Be Published
8AVZ
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Crystal structure of PksD, the trans-acting acyl hydrolase domain from the bacillaene trans-AT PKS (SeMet derivative)
分子名称: Polyketide biosynthesis acyltransferase homolog PksD, ZINC ION
著者Fage, C.D, Challis, G.L, Lewandowski, J, Jenner, M.
登録日2022-08-28
公開日2023-08-09
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural basis for acyl hydrolysis in trans-AT polyketide synthases
To Be Published
8AQR
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Native crystal structure of the N-terminal beta-hairpin docking (bHD) domain of the AerJ halogenase, from the aeruginosin biosynthetic assembly line
分子名称: AerJ, CHLORIDE ION
著者Fage, C.D, Lewandowski, J.R, Challis, G.L.
登録日2022-08-13
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Tandem halogenation and condensation in aeruginosin biosynthesis is directed by docking domain-mediated carrier protein recruitment
To Be Published
8AQQ
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SeMet-derived crystal structure of the N-terminal beta-hairpin docking (bHD) domain of the AerJ halogenase, from the aeruginosin biosynthetic assembly line
分子名称: AerJ, CHLORIDE ION
著者Fage, C.D, Lewandowski, J.R, Challis, G.L.
登録日2022-08-13
公開日2024-03-06
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Tandem halogenation and condensation in aeruginosin biosynthesis is directed by docking domain-mediated carrier protein recruitment
To Be Published
1ZEO
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Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with an Alpha-Aryloxyphenylacetic Acid Agonist
分子名称: (2S)-(4-ISOPROPYLPHENYL)[(2-METHYL-3-OXO-5,7-DIPROPYL-2,3-DIHYDRO-1,2-BENZISOXAZOL-6-YL)OXY]ACETATE, Peroxisome proliferator activated receptor gamma
著者Shi, G.Q, Dropinski, J.F, McKeever, B.M, Adams, A.D, MacNaul, K.L, Elbrecht, A, Berger, J.P, Zhou, G, Doebber, T.W.
登録日2005-04-19
公開日2006-04-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design and Synthesis of alpha-Aryloxyphenylacetic Acid Derivatives: A Novel Class of PPAR alpha/gamma Dual Agonists with Potent Antihyperglycemic and Lipid Modulating Activity
J.Med.Chem., 48, 2005
1ZG8
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Crystal Structure of (R)-2-(3-{[amino(imino)methyl]amino}phenyl)-3-sulfanylpropanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
分子名称: (2R)-2-(3-{[AMINO(IMINO)METHYL]AMINO}PHENYL)-3-SULFANYLPROPANOIC ACID, ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-04-20
公開日2005-07-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
2AIQ
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Crystal structure of benzamidine-inhibited protein C activator from the venom of copperhead snake Agkistrodon contortrix contortrix
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BENZAMIDINE, ...
著者Murakami, M.T, Arni, R.K.
登録日2005-07-30
公開日2005-09-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Thrombomodulin-independent Activation of Protein C and Specificity of Hemostatically Active Snake Venom Serine Proteinases: CRYSTAL STRUCTURES OF NATIVE AND INHIBITED AGKISTRODON CONTORTRIX CONTORTRIX PROTEIN C ACTIVATOR.
J.Biol.Chem., 280, 2005
2AQW
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Structure of putative orotidine-monophosphate-decarboxylase from Plasmodium yoelii (PY01515)
分子名称: IODIDE ION, SULFATE ION, putative orotidine-monophosphate-decarboxylase
著者Dong, A, Vedadi, M, Wasney, G, Zhao, Y, Lew, J, Alam, Z, Melone, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC)
登録日2005-08-18
公開日2005-08-30
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
1RE3
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Crystal Structure of Fragment D of BbetaD398A Fibrinogen with the Peptide Ligand Gly-His-Arg-Pro-Amide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2003-11-06
公開日2004-05-25
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
2BDD
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Crystal Structure of Holo-ACP-synthase from Plasmodium yoelii
分子名称: ACP-synthase
著者Dong, A, Melone, M, Zhao, Y, Lew, J, Koeieradzki, I, Alam, Z, Wasney, G, Vedadi, M, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Amani, M, Structural Genomics Consortium (SGC)
登録日2005-10-20
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007
2C6E
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Aurora A kinase activated mutant (T287D) in complex with a 5- aminopyrimidinyl quinazoline inhibitor
分子名称: N-{5-[(7-{[(2S)-2-HYDROXY-3-PIPERIDIN-1-YLPROPYL]OXY}-6-METHOXYQUINAZOLIN-4-YL)AMINO]PYRIMIDIN-2-YL}BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE 6
著者Pauptit, R.A, Pannifer, A.D, Breed, J, McMiken, H.H.J, Rowsell, S, Anderson, M.
登録日2005-11-09
公開日2006-01-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Sar and Inhibitor Complex Structure Determination of a Novel Class of Potent and Specific Aurora Kinase Inhibitors.
Bioorg.Med.Chem.Lett., 16, 2006
1Z5R
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Crystal Structure of Activated Porcine Pancreatic Carboxypeptidase B
分子名称: ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-03-18
公開日2005-07-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
1ZG9
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Crystal Structure of 5-{[amino(imino)methyl]amino}-2-(sulfanylmethyl)pentanoic acid Bound to Activated Porcine Pancreatic Carboxypeptidase B
分子名称: 5-{[AMINO(IMINO)METHYL]AMINO}-2-(SULFANYLMETHYL)PENTANOIC ACID, ZINC ION, procarboxypeptidase B
著者Adler, M, Bryant, J, Buckman, B, Islam, I, Larsen, B, Finster, S, Kent, L, May, K, Mohan, R, Yuan, S, Whitlow, M.
登録日2005-04-20
公開日2005-07-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
Biochemistry, 44, 2005
2BOH
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Crystal structure of factor Xa in complex with compound "1"
分子名称: 1-{[5-(5-CHLORO-2-THIENYL)ISOXAZOL-3-YL]METHYL}-N-(1-ISOPROPYLPIPERIDIN-4-YL)-1H-INDOLE-2-CARBOXAMIDE, CALCIUM ION, COAGULATION FACTOR XA
著者Nazare, M, Will, D.W, Matter, H, Schreuder, H, Ritter, K, Urmann, M, Essrich, M, Bauer, A, Wagner, M, Czech, J, Laux, V, Wehner, V.
登録日2005-04-11
公開日2006-04-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Probing the Subpockets of Factor Xa Reveals Two Binding Modes for Inhibitors Based on a 2-Carboxyindole Scaffold: A Study Combining Structure-Activity Relationship and X-Ray Crystallography.
J.Med.Chem., 48, 2005
1SDD
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Crystal Structure of Bovine Factor Vai
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ...
著者Adams, T.E, Hockin, M.F, Mann, K.G, Everse, S.J.
登録日2004-02-13
公開日2004-06-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function.
Proc.Natl.Acad.Sci.USA, 101, 2004
1RE4
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Crystal Structure of Fragment D of BbetaD398A Fibrinogen
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha/alpha-E chain, ...
著者Kostelansky, M.S, Betts, L, Gorkun, O.V, Lord, S.T.
登録日2003-11-06
公開日2004-05-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献BbetaGlu397 and BbetaAsp398 but not BbetaAsp432 are required for "B:b" interactions.
Biochemistry, 43, 2004
2B71
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Plasmodium yoelii cyclophilin-like protein
分子名称: CHLORIDE ION, cyclophilin-like protein
著者Dong, A, Finerty, P, Wasney, G, Vedadi, M, Lew, J, Zhao, Y, Kozieradzki, I, Melone, M, Alam, Z, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC)
登録日2005-10-03
公開日2005-10-11
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Mol.Biochem.Parasitol., 151, 2007

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