5VL4
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![BU of 5vl4 by Molmil](/molmil-images/mine/5vl4) | Accidental minimum contact crystal lattice formed by a redesigned protein oligomer | 分子名称: | T33-53H-B | 著者 | Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T. | 登録日 | 2017-04-24 | 公開日 | 2018-05-23 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering. Protein Sci., 29, 2020
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5IEN
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![BU of 5ien by Molmil](/molmil-images/mine/5ien) | Structure of CDL2.2, a computationally designed Vitamin-D3 binder | 分子名称: | 3-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANOL, CDL2.2, GLYCEROL | 著者 | Stoddard, B.L, Doyle, L.A. | 登録日 | 2016-02-25 | 公開日 | 2017-03-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.089 Å) | 主引用文献 | Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold. Protein Eng.Des.Sel., 31, 2018
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7BQS
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![BU of 7bqs by Molmil](/molmil-images/mine/7bqs) | Solution NMR structure of fold-U Nomur; de novo designed protein with an asymmetric all-alpha topology | 分子名称: | Nomur | 著者 | Kobayashi, N, Nagashima, T, Sakuma, K, Kosugi, T, Koga, R, Koga, N. | 登録日 | 2020-03-25 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design of complicated all-alpha protein structures Nat.Struct.Mol.Biol., 2024
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8T6C
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![BU of 8t6c by Molmil](/molmil-images/mine/8t6c) | Crystal structure of T33-18.2: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles | 分子名称: | T33-18.2 : A, T33-18.2 : B | 著者 | Bera, A.K, de Haas, R.J, Kang, A, Sankaran, B, King, N.P. | 登録日 | 2023-06-15 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UTK
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![BU of 8utk by Molmil](/molmil-images/mine/8utk) | IL-23R minibinder - 23R-B04dslf02IB | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 23R-B04dslf02IB, ... | 著者 | Bera, A.K, Berger, S.A, Kang, A, Baker, D. | 登録日 | 2023-10-31 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell, 2024
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6XSS
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![BU of 6xss by Molmil](/molmil-images/mine/6xss) | CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900 | 分子名称: | C4_nat_HFuse-7900 | 著者 | Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G. | 登録日 | 2020-07-16 | 公開日 | 2020-12-23 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun, 12, 2021
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6XT4
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![BU of 6xt4 by Molmil](/molmil-images/mine/6xt4) | |
6XNS
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![BU of 6xns by Molmil](/molmil-images/mine/6xns) | C3_crown-05 | 分子名称: | C3_crown-05 | 著者 | Bick, M.J, Hsia, Y, Sankaran, B, Baker, D. | 登録日 | 2020-07-04 | 公開日 | 2020-12-23 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun, 12, 2021
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8FIQ
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![BU of 8fiq by Molmil](/molmil-images/mine/8fiq) | |
8FVT
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![BU of 8fvt by Molmil](/molmil-images/mine/8fvt) | |
8FIH
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![BU of 8fih by Molmil](/molmil-images/mine/8fih) | |
8FIT
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![BU of 8fit by Molmil](/molmil-images/mine/8fit) | |
8FIN
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![BU of 8fin by Molmil](/molmil-images/mine/8fin) | |
7MWQ
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![BU of 7mwq by Molmil](/molmil-images/mine/7mwq) | Structure of De Novo designed beta sheet heterodimer LHD29A53/B53 | 分子名称: | LHD29A53, LHD29B53 | 著者 | Bera, A.K, Sahtoe, D.D, Kang, A, Praetorius, F, Baker, D. | 登録日 | 2021-05-17 | 公開日 | 2022-01-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Reconfigurable asymmetric protein assemblies through implicit negative design. Science, 375, 2022
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7MWR
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![BU of 7mwr by Molmil](/molmil-images/mine/7mwr) | Structure of De Novo designed beta sheet heterodimer LHD101A53/B4 | 分子名称: | LHD101A54, LHD101B4, MALONATE ION | 著者 | Bera, A.K, Sahtoe, D.D, Kang, A, Praetorius, F, Baker, D. | 登録日 | 2021-05-17 | 公開日 | 2022-01-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Reconfigurable asymmetric protein assemblies through implicit negative design. Science, 375, 2022
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8FG6
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7BQR
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![BU of 7bqr by Molmil](/molmil-images/mine/7bqr) | Solution NMR structure of fold-K Mussoc; de novo designed protein with an asymmetric all-alpha topology | 分子名称: | Mussoc | 著者 | Kobayashi, N, Nagashima, T, Sakuma, K, Kosugi, T, Koga, R, Koga, N. | 登録日 | 2020-03-25 | 公開日 | 2021-04-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Design of complicated all-alpha protein structures Nat.Struct.Mol.Biol., 2024
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8T6E
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![BU of 8t6e by Molmil](/molmil-images/mine/8t6e) | Crystal structure of T33-28.3: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles | 分子名称: | T33-28.3: A, T33-28.3: B | 著者 | Bera, A.K, de Haas, R.J, Kang, A, Sankaran, B, King, N.P. | 登録日 | 2023-06-15 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proc.Natl.Acad.Sci.USA, 121, 2024
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8T6N
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![BU of 8t6n by Molmil](/molmil-images/mine/8t6n) | Crystal structure of T33-27.1: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles | 分子名称: | T33-27.1 : A, T33-27.1 : B | 著者 | Bera, A.K, de Haas, R.J, Kang, A, Sankaran, B, King, N.P. | 登録日 | 2023-06-16 | 公開日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3.63 Å) | 主引用文献 | Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proc.Natl.Acad.Sci.USA, 121, 2024
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5HHC
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![BU of 5hhc by Molmil](/molmil-images/mine/5hhc) | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21/n | 分子名称: | D- Vascular endothelial growth factor-A, GLYCEROL, Vascular endothelial growth factor A | 著者 | Uppalapati, M, Lee, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | 登録日 | 2016-01-10 | 公開日 | 2016-03-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. Acs Chem.Biol., 11, 2016
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5HHD
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![BU of 5hhd by Molmil](/molmil-images/mine/5hhd) | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21 | 分子名称: | D-Peptide RFX037.D, D-Vascular endothelial growth factor, DI(HYDROXYETHYL)ETHER, ... | 著者 | Uppalapati, M, LEE, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | 登録日 | 2016-01-10 | 公開日 | 2016-03-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. Acs Chem.Biol., 11, 2016
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7ONE
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![BU of 7one by Molmil](/molmil-images/mine/7one) | Crystal structure of the self-assembled SAKe6BE designer protein | 分子名称: | SAKe6BE | 著者 | Wouters, S.M.L, Noguchi, H, Velpula, G, Clarke, D.E, Voet, A.R.D, De Feyter, S. | 登録日 | 2021-05-25 | 公開日 | 2022-12-14 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | SAKe: Computationally Designed Modular Protein Building Blocks for Macromolecular Assemblies To be published
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1ZSZ
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![BU of 1zsz by Molmil](/molmil-images/mine/1zsz) | Crystal structure of a computationally designed SspB heterodimer | 分子名称: | MAGNESIUM ION, Stringent starvation protein B homolog | 著者 | Bolon, D.N, Grant, R.A, Baker, T.A, Sauer, R.T. | 登録日 | 2005-05-25 | 公開日 | 2005-08-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Specificity versus stability in computational protein design. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1EIX
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![BU of 1eix by Molmil](/molmil-images/mine/1eix) | STRUCTURE OF OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE FROM E. COLI, CO-CRYSTALLISED WITH THE INHIBITOR BMP | 分子名称: | 1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID, OROTIDINE 5'-MONOPHOSPHATE DECARBOXYLASE | 著者 | Harris, P, Poulsen, J.C.N, Jensen, K.F, Larsen, S. | 登録日 | 2000-02-29 | 公開日 | 2000-03-15 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for the catalytic mechanism of a proficient enzyme: orotidine 5'-monophosphate decarboxylase. Biochemistry, 39, 2000
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1UAO
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![BU of 1uao by Molmil](/molmil-images/mine/1uao) | |