8FIT

Multi-state design of two-state switchable hinge proteins

Summary for 8FIT

• Entry DOI: 10.2210/pdb8fit/pdb
• Descriptor: cs074A (2 entities in total)
• Functional Keywords: de novo protein, metamorphic proteins, switchable hinge proteins, protein dynamics
• Biological source: synthetic construct
• Total number of polymer chains: 4
• Total formula weight: 117462.40

Authors

Bera, A.K.,Praetorius, F.,Baker, D. (deposition date: 2022-12-16, release date: 2023-08-16, Last modification date: 2024-03-06)

• Primary citation: Praetorius, F.,Leung, P.J.Y.,Tessmer, M.H.,Broerman, A.,Demakis, C.,Dishman, A.F.,Pillai, A.,Idris, A.,Juergens, D.,Dauparas, J.,Li, X.,Levine, P.M.,Lamb, M.,Ballard, R.K.,Gerben, S.R.,Nguyen, H.,Kang, A.,Sankaran, B.,Bera, A.K.,Volkman, B.F.,Nivala, J.,Stoll, S.,Baker, D.; Design of stimulus-responsive two-state hinge proteins.; Science, 381:754-760, 2023; PubMed: 37590357; DOI: 10.1126/science.adg7731

Experimental method

X-RAY DIFFRACTION (2.75 Å)