4DN4
 
 | | Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a | | 分子名称: | ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ... | | 著者 | Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. | | 登録日 | 2012-02-08 | | 公開日 | 2012-10-03 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
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8WA5
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5N7G
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5NCQ
 | | Structure of the (SR) Ca2+-ATPase bound to a Tetrahydrocarbazole and TNP-ATP | | 分子名称: | (1~{S})-~{N}-[(4-bromophenyl)methyl]-7-(trifluoromethyloxy)-2,3,4,9-tetrahydro-1~{H}-carbazol-1-amine, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM ION, ... | | 著者 | Bublitz, M, Kjellerup, L, O'Hanlon Cohrt, K, Gordon, S, Mortensen, A.L, Clausen, J.D, Pallin, D, Hansen, J.B, Brown, W.D, Fuglsang, A, Winther, A.-M.L. | | 登録日 | 2017-03-06 | | 公開日 | 2018-01-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Tetrahydrocarbazoles are a novel class of potent P-type ATPase inhibitors with antifungal activity.
PLoS ONE, 13, 2018
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4ZKH
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5N60
 | | Cryo-EM structure of RNA polymerase I in complex with Rrn3 and Core Factor (Orientation I) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Engel, C, Gubbey, T, Neyer, S, Sainsbury, S, Oberthuer, C, Baejen, C, Bernecky, C, Cramer, P. | | 登録日 | 2017-02-14 | | 公開日 | 2017-04-05 | | 最終更新日 | 2018-10-03 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | Structural Basis of RNA Polymerase I Transcription Initiation.
Cell, 169, 2017
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2HJJ
 | | Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397. | | 分子名称: | Hypothetical protein ykfF | | 著者 | Swapna, G.V.T, Aramini, J.M, Zhao, L, Cunningham, K, Janjua, H, Ma, L.-C, Xiao, R, Baran, M.C, Acton, T.B, Liu, J, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2006-06-30 | | 公開日 | 2006-08-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397.
To be Published
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4ZKX
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4ZN0
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5NFT
 | | Glucocorticoid Receptor in complex with AZD5423 | | 分子名称: | 1,2-ETHANEDIOL, 2,2,2-tris(fluoranyl)-~{N}-[(1~{R},2~{S})-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]ethanamide, Glucocorticoid receptor, ... | | 著者 | Edman, K, Wissler, L. | | 登録日 | 2017-03-15 | | 公開日 | 2017-10-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases.
J. Med. Chem., 60, 2017
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2HMB
 | | THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN MUSCLE FATTY ACID-BINDING PROTEIN | | 分子名称: | MUSCLE FATTY ACID BINDING PROTEIN, PALMITIC ACID | | 著者 | Zanotti, G, Scapin, G, Spadon, P, Veerkamp, J.H, Sacchettini, J.C. | | 登録日 | 1992-09-11 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three-dimensional structure of recombinant human muscle fatty acid-binding protein.
J.Biol.Chem., 267, 1992
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4ZWI
 | | Surface Lysine Acetylated Human Carbonic Anhydrase II in Complex with a Sulfamate-Based Inhibitor | | 分子名称: | (6R)-1-O-acetyl-2,6-anhydro-6-{[4-(sulfamoyloxy)piperidin-1-yl]sulfonyl}-L-glucitol, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... | | 著者 | Lomelino, C.L, Mahon, B.P, McKenna, M. | | 登録日 | 2015-05-19 | | 公開日 | 2015-08-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Observed surface lysine acetylation of human carbonic anhydrase II expressed in Escherichia coli.
Protein Sci., 24, 2015
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2Q1F
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2HN7
 | | HLA-A*1101 in complex with HBV peptide homologue | | 分子名称: | Beta-2-microglobulin, DNA polymerase PEPTIDE HOMOLOGUE, HLA class I histocompatibility antigen, ... | | 著者 | Blicher, T. | | 登録日 | 2006-07-12 | | 公開日 | 2006-11-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of HLA-A*1101 in complex with a hepatitis B peptide homologue.
Acta Crystallogr.,Sect.F, 62, 2006
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4ZWZ
 | | Engineered Carbonic Anhydrase IX mimic in complex with a glucosyl sulfamate inhibitor | | 分子名称: | Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ZINC ION, ... | | 著者 | Mahon, B.P, Lomelino, C.L, Driscoll, J.M, McKenna, R. | | 登録日 | 2015-05-19 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Mapping Selective Inhibition of the Cancer-Related Carbonic Anhydrase IX Using Structure-Activity Relationships of Glucosyl-Based Sulfamates.
J.Med.Chem., 58, 2015
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5N0Z
 | | hPAD4 crystal complex with AFM-41a | | 分子名称: | 2-ethyl-~{N}-[(1~{S})-4-(2-fluoranylethanimidoylamino)-1-(4-methoxy-1-methyl-benzimidazol-2-yl)butyl]-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, CALCIUM ION, Protein-arginine deiminase type-4, ... | | 著者 | Beaumont, E, Kerry, P, Thompson, P, Muth, A, Subramanian, V, Nagar, M, Srinath, H, Clancy, K, Parelkar, S. | | 登録日 | 2017-02-03 | | 公開日 | 2017-05-24 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | Development of a Selective Inhibitor of Protein Arginine Deiminase 2.
J. Med. Chem., 60, 2017
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7K3I
 | | Cellular retinol-binding protein 2 (CRBP2) in complex with 2-lauroylglycerol | | 分子名称: | 1,3-dihydroxypropan-2-yl dodecanoate, Retinol-binding protein 2 | | 著者 | Adams, C, Silvaroli, J.A, Banarjee, S, Golczak, M. | | 登録日 | 2020-09-11 | | 公開日 | 2021-03-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands.
J.Lipid Res., 62, 2021
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7JX2
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5N1B
 | | hPAD4 crystal complex with AFM-14a | | 分子名称: | CALCIUM ION, Protein-arginine deiminase type-4, SULFATE ION, ... | | 著者 | Beaumont, E, Kerry, P, Thompson, P, Muth, A, Subramanian, V, Nagar, M, Srinath, H, Clancy, K, Parelkar, S. | | 登録日 | 2017-02-06 | | 公開日 | 2017-05-24 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Development of a Selective Inhibitor of Protein Arginine Deiminase 2.
J. Med. Chem., 60, 2017
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2HLA
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4F7T
 | | Crystal Structure of HLA-A*2402 Complexed with a Newly Identified Peptide from 2009 H1N1 PB1 (498-505) | | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | | 著者 | Liu, J, Zhang, S, Tan, S, Yi, Y, Wu, B, Zhu, F, Wang, H, Qi, J, Gao, G.F. | | 登録日 | 2012-05-16 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cross-Allele Cytotoxic T Lymphocyte Responses against 2009 Pandemic H1N1 Influenza A Virus among HLA-A24 and HLA-A3 Supertype-Positive Individuals.
J.Virol., 86, 2012
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5NN3
 | | Crystal structure of human lysosomal acid-alpha-glucosidase, GAA | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Roig-Zamboni, V, Cobucci-Ponzano, B, Iacono, R, Ferrara, M.C, Germany, S, Parenti, G, Bourne, Y, Moracci, M. | | 登録日 | 2017-04-08 | | 公開日 | 2017-10-25 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of human lysosomal acid alpha-glucosidase-a guide for the treatment of Pompe disease.
Nat Commun, 8, 2017
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5N6O
 | | Wild type human Rac1-GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 | | 著者 | Cherfils, J, Ferrandez, Y. | | 登録日 | 2017-02-15 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule.
Sci Rep, 7, 2017
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4ZS3
 | | Structural complex of 5-aminofluorescein bound to the FTO protein | | 分子名称: | 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | | 著者 | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | | 登録日 | 2015-05-13 | | 公開日 | 2015-11-04 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
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4XLS
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