6MFV
 
 | | Crystal structure of the Signal Transduction ATPase with Numerous Domains (STAND) protein with a tetratricopeptide repeat sensor PH0952 from Pyrococcus horikoshii | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, tetratricopeptide repeat sensor PH0952 | | 著者 | Lisa, M.N, Alzari, P.M, Haouz, A, Danot, O. | | 登録日 | 2018-09-12 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Double autoinhibition mechanism of signal transduction ATPases with numerous domains (STAND) with a tetratricopeptide repeat sensor.
Nucleic Acids Res., 47, 2019
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7UZD
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5CH8
 | | Crystal structure of MDLA N225Q mutant form Penicillium cyclopium | | 分子名称: | CHLORIDE ION, GLYCEROL, Mono- and diacylglycerol lipase, ... | | 著者 | Xu, J, Xu, H, Hou, S, Liu, J. | | 登録日 | 2015-07-10 | | 公開日 | 2016-04-20 | | 最終更新日 | 2017-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | Lipase-Driven Epoxidation Is A Two-Stage Synergistic Process
ChemistrySelect, 4, 2016
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7OJZ
 | | SaFtsZ complexed with GMPCP | | 分子名称: | 1,2-ETHANEDIOL, Cell division protein FtsZ, PHOSPHOMETHYLPHOSPHONIC ACID GUANOSYL ESTER, ... | | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | | 登録日 | 2021-05-17 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
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7UU6
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8Q6W
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7MEE
 | | CDD-1 beta-lactamase in imidazole/MPD 6 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7OL9
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6LW8
 | | Structural basis for domain rotation during adenylation of active site K123 and fragment library screening against NAD+ -dependent DNA ligase from Mycobacterium tuberculosis | | 分子名称: | (4R)-4-(4-fluorophenyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine, DNA ligase A, GLYCEROL, ... | | 著者 | Ramachandran, R, Afsar, M, Shukla, A. | | 登録日 | 2020-02-07 | | 公開日 | 2021-02-10 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | | 主引用文献 | Structure based identification of first-in-class fragment inhibitors that target the NMN pocket of M. tuberculosis NAD + -dependent DNA ligase A.
J.Struct.Biol., 213, 2021
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8KG2
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8TA1
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7MEC
 | | CDD-1 beta-lactamase in imidazole/MPD 4 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7UDQ
 | | Crystal structure of COQ8A-CA157 inhibitor complex in space group P1 | | 分子名称: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial, ... | | 著者 | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | | 登録日 | 2022-03-20 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Small-molecule inhibition of the archetypal UbiB protein COQ8.
Nat.Chem.Biol., 19, 2023
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7XQK
 | | The Crystal Structure of CDK3 and CyclinE1 Complex from Biortus. | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, G1/S-specific cyclin-E1, GLYCEROL, ... | | 著者 | Gui, W, Wang, F, Cheng, W, Gao, J, Huang, Y. | | 登録日 | 2022-05-07 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The Crystal Structure of CDK3 and CyclinE1 Complex from Biortus.
To Be Published
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7MDJ
 | | The structure of KcsA in complex with a synthetic Fab | | 分子名称: | Fab heavy chain, Fab light chain, POTASSIUM ION, ... | | 著者 | Rohaim, A, Slezak, T, Blackowicz, L, Kossiakoff, A, Roux, B. | | 登録日 | 2021-04-05 | | 公開日 | 2022-02-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
J.Gen.Physiol., 154, 2022
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7UU8
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8TY3
 | | MI-31 ligand bound to SARS-CoV-2 Mpro | | 分子名称: | (1S,3aR,6aS)-2-[(3,4-dichlorophenoxy)acetyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}octahydrocyclopenta[c]pyrrole-1-carboxamide, 3C-like proteinase nsp5 | | 著者 | Blankenship, L.R, Liu, W.R. | | 登録日 | 2023-08-24 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | MI-31 bound to SARS-CoV-2 Mpro
To Be Published
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7MEF
 | | CDD-1 beta-lactamase in imidazole/MPD 10 minute avibactam complex | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | | 著者 | Smith, C.A, Vakulenko, S.B. | | 登録日 | 2021-04-06 | | 公開日 | 2022-02-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | In Crystallo Time-Resolved Interaction of the Clostridioides difficile CDD-1 enzyme with Avibactam Provides New Insights into the Catalytic Mechanism of Class D beta-lactamases.
Acs Infect Dis., 7, 2021
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7M23
 | | Human carbonic anhydrase II in complex with troglitazone | | 分子名称: | (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE, Carbonic anhydrase 2, ZINC ION | | 著者 | Mueller, S.L, Peat, T.S. | | 登録日 | 2021-03-16 | | 公開日 | 2022-02-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The Glitazone Class of Drugs as Carbonic Anhydrase Inhibitors-A Spin-Off Discovery from Fragment Screening.
Molecules, 26, 2021
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8KB0
 | | Crystal structure of 01JD-AEAIIVAMV | | 分子名称: | Beta2-microglobulin, MHC class I antigen alpha chain, peptide of AIV | | 著者 | Tang, Z, Zhang, N. | | 登録日 | 2023-08-03 | | 公開日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | The impact of micropolymorphism in Anpl-UAA on structural stability and peptide presentation.
Int.J.Biol.Macromol., 267, 2024
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8Q7K
 | | IRGQ LIR2 peptide in complex with LC3B | | 分子名称: | 1,2-ETHANEDIOL, Immunity-related GTPase family Q protein, Microtubule-associated proteins 1A/1B light chain 3B | | 著者 | Misra, M, Bailey, H.J, Pomirska, J, Dikic, I. | | 登録日 | 2023-08-16 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Tumor immune evasion through IRGQ-directed autophagy
To Be Published
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7UUC
 | | Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI19 | | 分子名称: | 3C-like proteinase nsp5, N-[(benzyloxy)carbonyl]-3-methyl-L-valyl-3-cyclopropyl-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-alaninamide | | 著者 | Yang, K.S, Liu, W.R. | | 登録日 | 2022-04-28 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Novel Y-Shaped, S-O-N-O-S-Bridged Cross-Link between Three Residues C22, C44, and K61 Is Frequently Observed in the SARS-CoV-2 Main Protease.
Acs Chem.Biol., 18, 2023
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7MO6
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7UU7
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8QPT
 | | Crystal structure of pyrophosphatase from Ogataea parapolymorpha | | 分子名称: | GLYCEROL, MAGNESIUM ION, inorganic diphosphatase | | 著者 | Matyuta, I.O, Rodina, E.V, Vorobyeva, N.N, Kurilova, S.A, Bezpalaya, E.Y, Boyko, K.M. | | 登録日 | 2023-10-03 | | 公開日 | 2024-09-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The crystal structure of yeast mitochondrial type pyrophosphatase provides a model to study pathological mutations in its human ortholog.
Biochem.Biophys.Res.Commun., 738, 2024
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