8Q7K

IRGQ LIR2 peptide in complex with LC3B

Summary for 8Q7K

Entry DOI	10.2210/pdb8q7k/pdb
Descriptor	Microtubule-associated proteins 1A/1B light chain 3B, Immunity-related GTPase family Q protein, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	autophagy, lc3b, lir, irgq, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	31780.44
Authors	Misra, M.,Bailey, H.J.,Pomirska, J.,Dikic, I. (deposition date: 2023-08-16, release date: 2024-08-28)
Primary citation	Herhaus, L.,Gestal-Mato, U.,Eapen, V.V.,Macinkovic, I.,Bailey, H.J.,Prieto-Garcia, C.,Misra, M.,Jacomin, A.,Covarrubias-Pinto, A.,Bagaric, I.,Vollrath, J.,Bhaskara, R.M.,Husnjak, K.,Zoellner, J.,Gikandi, A.,Heden van Noort, G.J.,Langer, J.,Weigert, A.,Harper, J.W.,Mancias, J.D.,Dikic, I. Tumor immune evasion through IRGQ-directed autophagy To Be Published,
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation