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4O5L
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BU of 4o5l by Molmil
Crystal structure of broadly neutralizing antibody F045-092
分子名称: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5045 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4O5I
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BU of 4o5i by Molmil
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/361/2011 (H3N2) influenza hemagglutinin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab F045-092 heavy chain, ...
著者Lee, P.S, Wilson, I.A.
登録日2013-12-19
公開日2014-04-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (6.501 Å)
主引用文献Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4NPY
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BU of 4npy by Molmil
Crystal structure of germline Fab PGT121, a putative precursor of the broadly reactive and potent HIV-1 neutralizing antibody
分子名称: GLYCEROL, germline PGT121 heavy chain, germline PGT121 light chain
著者Julien, J.-P, Diwanji, D.C, Wilson, I.A.
登録日2013-11-22
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.
Plos Pathog., 9, 2013
2GK0
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BU of 2gk0 by Molmil
Structure of Catalytic Elimination Antibody 13G5 from a twinned crystal in space group C2
分子名称: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain
著者Debler, E.W, Wilson, I.A.
登録日2006-03-31
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
4NHU
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BU of 4nhu by Molmil
The M33 TCR p3M33l/H-2 Ld Complex
分子名称: 2C m33 alpha VmCh chimera, 2C m33 beta VmCh chimera, H-2 class I histocompatibility antigen, ...
著者Birnbaum, M.E, Adams, J.J, Garcia, K.C.
登録日2013-11-05
公開日2015-05-06
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Interrogating TCR Signal Strength and Cross-Reactivity by Yeast Display of pMHC
To be Published
2GSI
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BU of 2gsi by Molmil
Crystal Structure of a Murine Fab in Complex with an 11 Residue Peptide Derived from Staphylococcal Nuclease
分子名称: Immunoglobulin (gamma) heavy chain (VH + CH1 fragment), Immunoglobulin (kappa) light chain, SODIUM ION, ...
著者Armstrong, A.A, Amzel, L.M.
登録日2006-04-26
公開日2006-05-16
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal Structure of a Murine Fab in Complex with an 11 Residue Peptide Derived from Staphylococcal Nuclease
To be Published
4NQC
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BU of 4nqc by Molmil
Crystal structure of TCR-MR1 ternary complex and covalently bound 5-(2-oxopropylideneamino)-6-D-ribitylaminouracil
分子名称: 1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol, Beta-2-microglobulin, Major histocompatibility complex class I-related gene protein, ...
著者Birkinshaw, R.W, Rossjohn, J.
登録日2013-11-25
公開日2014-04-16
最終更新日2014-11-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T-cell activation by transitory neo-antigens derived from distinct microbial pathways.
Nature, 509, 2014
6BJ8
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BU of 6bj8 by Molmil
TCR55 in complex with Pep20/HLA-B35
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Jude, K.M, Sibener, L.V, Yang, X, Garcia, K.C.
登録日2017-11-05
公開日2018-07-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
Cell, 174, 2018
2H32
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BU of 2h32 by Molmil
Crystal structure of the pre-B cell receptor
分子名称: Immunoglobulin heavy chain, Immunoglobulin iota chain, Immunoglobulin omega chain, ...
著者Bankovich, A.J.
登録日2006-05-22
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Insight into Pre-B Cell Receptor Function
Science, 316, 2007
6CQN
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BU of 6cqn by Molmil
Crystal structure of F5 TCR -DR11-RQ13 peptide complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, F5 alpha chain, ...
著者Farenc, C, Gras, S, Rossjohn, J.
登録日2018-03-15
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
Sci Immunol, 3, 2018
6CQQ
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BU of 6cqq by Molmil
Crystal structure of F24 TCR -DR15-RQ13 peptide complex
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, F24 alpha chain, ...
著者Farenc, C, Gras, S, Rossjohn, J.
登録日2018-03-16
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
Sci Immunol, 3, 2018
2FD6
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BU of 2fd6 by Molmil
Structure of Human Urokinase Plasminogen Activator in Complex with Urokinase Receptor and an anti-upar antibody at 1.9 A
分子名称: 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ...
著者Huang, M, Huai, Q, Li, Y.
登録日2005-12-13
公開日2006-02-21
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of human urokinase plasminogen activator in complex with its receptor
Science, 311, 2006
4MNH
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BU of 4mnh by Molmil
Structure of the DP10.7 TCR
分子名称: Human nkt tcr alpha chain, T-cell receptor gamma chain V region PT-gamma-1/2, Human nkt tcr beta chain
著者Luoma, A.M, Adams, E.J.
登録日2013-09-10
公開日2013-12-18
最終更新日2017-06-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells.
Immunity, 39, 2013
6C5H
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BU of 6c5h by Molmil
S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Evans, S.V, Haji-Ghassemi, O.
登録日2018-01-16
公開日2019-01-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019
4MYW
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BU of 4myw by Molmil
Structure of HSV-2 gD bound to nectin-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein D, ...
著者Lu, G, Zhang, N, Qi, J, Li, Y, Chen, Z, Zheng, C, Yan, J, Gao, G.F.
登録日2013-09-28
公開日2014-10-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.189 Å)
主引用文献Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition.
J.Virol., 88, 2014
6CBJ
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BU of 6cbj by Molmil
Crystal Structure of DH270.3 Fab in complex with Man9
分子名称: DH270.3 Fab heavy chain, DH270.3 Fab light chain, PHOSPHATE ION, ...
著者Fera, D, Harrison, S.C.
登録日2018-02-03
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope.
Nat Commun, 9, 2018
6ARU
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BU of 6aru by Molmil
Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab mutant heavy chain Fab fragment,Immunoglobulin gamma-1 heavy chain, ...
著者Christie, M, Christ, D.
登録日2017-08-23
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Cetuximab Fab mutant in complex with EGFR extracellular domain
To Be Published
6AXP
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BU of 6axp by Molmil
Structure of cetuximab with aminoheptanoic acid-linked n-octylarginine meditope variant
分子名称: SULFATE ION, cetuximab Fab heavy chain, cetuximab Fab light chain, ...
著者Bzymek, K.P, Williams, J.C.
登録日2017-09-07
公開日2017-12-13
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.484 Å)
主引用文献Meditope-Fab interaction: threading the hole.
Acta Crystallogr F Struct Biol Commun, 73, 2017
4N0C
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BU of 4n0c by Molmil
42F3 TCR pCPE3/H-2Ld complex
分子名称: 42F3 VmCh alpha, 42F3 VmCh beta, H-2 class I histocompatibility antigen, ...
著者Birnbaum, M.E, Adams, J.J, Garcia, K.C.
登録日2013-10-01
公開日2015-08-19
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
2G5B
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BU of 2g5b by Molmil
Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide.
分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6A7 Fab Heavy Chain, 6A7 Fab Light Chain, ...
著者Peyerl, F.W, Dai, S, Murphy, G.A, Marrack, P, Kappler, J.W.
登録日2006-02-22
公開日2006-07-25
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex.
Cell Death Differ., 14, 2007
4N5E
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BU of 4n5e by Molmil
42F3 TCR pCPA12/H-2Ld complex
分子名称: 42F3 alpha VmCh, 42F3 beta VmCh, H-2 class I histocompatibility antigen, ...
著者Birnbaum, M.E, Adams, J.J, Garcia, K.C.
登録日2013-10-09
公開日2015-08-19
最終更新日2018-09-26
実験手法X-RAY DIFFRACTION (3.059 Å)
主引用文献Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.
Nat. Immunol., 17, 2016
2H2S
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BU of 2h2s by Molmil
Crystal Structure of E148A mutant of CLC-ec1 in SeCN-
分子名称: CLC Cl transporter, FAB fragment, heavy chain, ...
著者Nguitragool, W, Miller, C.
登録日2006-05-19
公開日2006-05-30
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions
J.Mol.Biol., 362, 2006
6CPH
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BU of 6cph by Molmil
Crystal structure of the F24 TCR
分子名称: ACETATE ION, SULFATE ION, TCR alpha chain, ...
著者Farenc, C, Gras, S, Rossjohn, J.
登録日2018-03-13
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献CD4+T cell-mediated HLA class II cross-restriction in HIV controllers.
Sci Immunol, 3, 2018
2H8P
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BU of 2h8p by Molmil
Structure of a K channel with an amide to ester substitution in the selectivity filter
分子名称: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB heavy chain, FAB light chain, ...
著者Valiyaveetil, F.I, MacKinnon, R, Muir, T.W.
登録日2006-06-07
公開日2006-09-12
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
J.Am.Chem.Soc., 128, 2006
6CW6
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Structure of alpha-GC[8,18] bound by CD1d and in complex with the Va14Vb8.2 TCR
分子名称: (2S,3S,4R)-N-OCTANOYL-1-[(ALPHA-D-GALACTOPYRANOSYL)OXY]-2-AMINO-OCTADECANE-3,4-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, J, Zajonc, D.
登録日2018-03-29
公開日2019-04-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A molecular switch in mouse CD1d modulates natural killer T cell activation by alpha-galactosylsphingamides.
J.Biol.Chem., 294, 2019

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