PDB: 31311 件ウェブページステータス検索Chemie searchBIRD

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6M8T	Crystal structure of UbiX-like FMN prenyltransferase AF1214 from Archaeoglobus fulgidus, FMN complex 分子名称: FLAVIN MONONUCLEOTIDE, Flavin prenyltransferase UbiX, PHOSPHATE ION 著者 Stogios, P.J, Skarina, T, Khusnutidnova, A, Wawrzak, Z, Yakunin, A.F, Savchenko, A. 登録日 2018-08-22 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Crystal structure of UbiX-like FMN prenyltransferase AF1214 from Archaeoglobus fulgidus, FMN complex To Be Published
7OKL	Crystal structure of human BCL6 BTB domain in complex with compound 13e 分子名称: 1,2-ETHANEDIOL, 2-chloranyl-4-[[1-methyl-2-oxidanylidene-4-[[(1R)-1-pyrimidin-2-ylethyl]amino]quinolin-6-yl]amino]pyridine-3-carbonitrile, ALA-TRP-VAL-ILE-PRO-ALA, ... 著者 Rodrigues, M.J, Le Bihan, Y.-V, van Montfort, R.L.M. 登録日 2021-05-17 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket. J.Med.Chem., 64, 2021
8JQ4	Crystal structure of Lactobacillus rhamnosus L-rhamnose isomerase in complex with L-rhamnose 分子名称: L-rhamnose isomerase, MANGANESE (II) ION, alpha-L-rhamnopyranose, ... 著者 Yoshida, H, Yoshihara, A. 登録日 2023-06-13 公開日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 X-ray structure and characterization of a probiotic Lactobacillus rhamnosus Probio-M9 L-rhamnose isomerase. Appl.Microbiol.Biotechnol., 108, 2024
5CMT	Fic protein from Neisseria meningitidis (NmFic) mutant E156R Y183F in dimeric form 分子名称: Adenosine monophosphate-protein transferase NmFic, CHLORIDE ION, GLYCEROL 著者 Stanger, F.V, Schirmer, T. 登録日 2015-07-17 公開日 2016-01-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (0.99 Å) 主引用文献 Intrinsic regulation of FIC-domain AMP-transferases by oligomerization and automodification. Proc.Natl.Acad.Sci.USA, 113, 2016
5FX5	Novel inhibitors of human rhinovirus 3C protease 分子名称: GLYCEROL, RHINOVIRUS 3C PROTEASE, TETRAETHYLENE GLYCOL, ... 著者 Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q. 登録日 2016-02-24 公開日 2016-06-22 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease. Bioorg.Med.Chem.Lett., 26, 2016
7OTA	HIV-1 REVERSE TRANSCRIPTASE COMPLEX WITH DNA AND INHIBITOR RMC-230 分子名称: ((2-(6-amino-9H-purin-9-yl)ethyl)-L-seryl)phosphoramidic acid, DNA (5'-D(*CP*AP*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*(MRG)*CP*GP*CP*CP*(DDG))-3'), DNA (5'-D(P*GP*GP*TP*CP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*CP*TP*G)-3'), ... 著者 Martinez, S.E, Singh, A.K, Gu, W, Das, K. 登録日 2021-06-09 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Exploring the dNTP -binding site of HIV-1 reverse transcriptase for inhibitor design. Eur.J.Med.Chem., 225, 2021
5TCS	Crystal structure of a Dwarf Ndc80 Tetramer 分子名称: Kinetochore protein NDC80, Kinetochore protein NUF2, Kinetochore protein SPC24, ... 著者 Valverde, R, Harrison, S.C. 登録日 2016-09-15 公開日 2016-11-23 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (2.8313 Å) 主引用文献 Conserved Tetramer Junction in the Kinetochore Ndc80 Complex. Cell Rep, 17, 2016
5BZ7	X-ray crystal structure of a continuously hydrogen bonded 14mer DNA lattice. 分子名称: DNA (5'-D(*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*GP*AP*GP*A)-3'), MAGNESIUM ION 著者 Saoji, M, Paukstelis, P.J. 登録日 2015-06-11 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Sequence-dependent structural changes in a self-assembling DNA oligonucleotide. Acta Crystallogr.,Sect.D, 71, 2015
6MA3	Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26) and inhibitor 2a 分子名称: 4-{2-[(1R)-2-{(carboxymethyl)[(thiophen-2-yl)methyl]amino}-2-oxo-1-{[(2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]amino}ethyl]phenoxy}butanoic acid, Host Cell Factor 1 peptide, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit 著者 Martin, S.E.S, Lazarus, M.B, Walker, S. 登録日 2018-08-25 公開日 2018-10-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure-Based Evolution of Low Nanomolar O-GlcNAc Transferase Inhibitors. J. Am. Chem. Soc., 140, 2018
5BZB	NavMs voltage-gated sodium channel pore and C-terminal domain 分子名称: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ... 著者 Naylor, C.E, Bagneris, C, Wallace, B.A. 登録日 2015-06-11 公開日 2016-02-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular basis of ion permeability in a voltage-gated sodium channel. Embo J., 35, 2016
8TFW	FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, boronic acid-based compound N34 bound 分子名称: Fluorophosphonate-binding serine hydrolase E, MAGNESIUM ION, [5-(trifluoromethyl)thiophen-2-yl]boronic acid 著者 Fellner, M. 登録日 2023-07-12 公開日 2024-07-24 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, boronic acid-based compound N34 bound To Be Published
6MAC	Ternary structure of GDF11 bound to ActRIIB-ECD and Alk5-ECD 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2B, Growth/differentiation factor 11, ... 著者 Goebel, E.J, Thompson, T.B. 登録日 2018-08-27 公開日 2019-07-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity. Proc.Natl.Acad.Sci.USA, 116, 2019
5G0J	Crystal structure of Danio rerio HDAC6 CD1 and CD2 (linker intact) in complex with Nexturastat A 分子名称: CHLORIDE ION, HDAC6, NEXTURASTAT A, ... 著者 Miyake, Y, Keusch, J.J, Wang, L, Saito, M, Hess, D, Wang, X, Melancon, B.J, Helquist, P, Gut, H, Matthias, P. 登録日 2016-03-18 公開日 2016-07-27 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structural Insights Into Hdac6 Tubulin Deacetylation and its Selective Inhibition Nat.Chem.Biol., 12, 2016
5G0U	InhA in complex with a DNA encoded library hit 分子名称: 5-[(4-fluoranyl-3-phenoxy-phenyl)methylamino]-~{N}-methyl-6-[(1-pyridin-2-ylpiperidin-4-yl)amino]pyridine-3-carboxamide, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Read, J.A, Breed, J. 登録日 2016-03-22 公開日 2016-11-30 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Discovery of Cofactor-Specific, Bactericidal Mycobacterium Tuberculosis Inha Inhibitors Using DNA-Encoded Library Technology Proc.Natl.Acad.Sci.USA, 113, 2016
7MP8	Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 in the non-phosphorylated state 分子名称: SULFATE ION, Serine/threonine-protein kinase PINK1, mitochondrial-like Protein 著者 Rasool, S, Veyron, S, Trempe, J.F. 登録日 2021-05-04 公開日 2021-12-01 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex. Mol.Cell, 82, 2022
5FQA	Crystal Structure of Bacillus cereus Metallo-Beta-Lactamase II 分子名称: 1,2-ETHANEDIOL, BETA-LACTAMASE 2, FE (III) ION, ... 著者 Cahill, S.T, Brem, J, McDonough, M.A, Schofield, C.J. 登録日 2015-12-08 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Use of ferrous iron by metallo-beta-lactamases. J. Inorg. Biochem., 163, 2016
6MAK	HBO1 is required for the maintenance of leukaemia stem cells 分子名称: ACETYL COENZYME *A, BRD1 protein, Histone acetyltransferase KAT7, ... 著者 Ren, B, Peat, T.S, Monahan, B, Dawson, M, Street, I. 登録日 2018-08-27 公開日 2019-12-25 最終更新日 2020-01-22 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 HBO1 is required for the maintenance of leukaemia stem cells. Nature, 577, 2020
8TMW	HTLV-1 capsid protein N-terminal domain triclinic crystal form with sulphate ion 分子名称: SULFATE ION, capsid protein p24 著者 Yu, R.J, Li, N, Jacques, D.A. 登録日 2023-07-31 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 HTLV-1 capsid protein N-terminal domain triclinic crystal form with sulphate ion To Be Published
5FRM	Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ384 (compound 4a) 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-azanylidene-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide, 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP *TP*CP*GP*CP*A)-3', ... 著者 Maskell, D.P, Pye, V.E, Cherepanov, P. 登録日 2015-12-18 公開日 2016-02-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 HIV-1 Integrase Strand Transfer Inhibitors with Reduced Susceptibility to Drug Resistant Mutant Integrases. Acs Chem.Biol., 11, 2016
8JNU	Crystal structure of V30G mutated human transthyretin 分子名称: MAGNESIUM ION, Transthyretin 著者 Mizuguchi, M, Yamada, S, Obita, T. 登録日 2023-06-06 公開日 2024-04-17 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Trypsin-induced aggregation of transthyretin Valine 30 variants associated with hereditary amyloidosis. Febs J., 291, 2024
8QIX	Structure of Mycobacterium abscessus Phosphopantetheine adenylyltransferase in complex with inhibitor 分子名称: 3-(3-methylindol-1-yl)-~{N}-(4-phenoxyphenyl)sulfonyl-propanamide, Phosphopantetheine adenylyltransferase 著者 Thomas, S.E, McCarthy, W.J, Coyne, A.G, Blundell, T.L. 登録日 2023-09-12 公開日 2024-07-24 最終更新日 2024-09-11 実験手法 X-RAY DIFFRACTION (1.579 Å) 主引用文献 A Fragment-Based Competitive 19 F LB-NMR Platform For Hotspot-Directed Ligand Profiling. Angew.Chem.Int.Ed.Engl., 63, 2024
7MPY	Crystal structure of cytosolic HPPK-DHPS from A.thaliana 分子名称: Folate synthesis bifunctional protein 著者 Vadlamani, G, Bond, C.S. 登録日 2021-05-05 公開日 2021-12-08 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of Arabidopsis thaliana HPPK/DHPS, a bifunctional enzyme and target of the herbicide asulam. Plant Commun., 3, 2022
8U1I	Crystal structure of SyoA bound to 4-methylsyringol 分子名称: 2,6-dimethoxy-4-methylphenol, Cytochrome P450, NITRATE ION, ... 著者 Harlington, A.C, Shearwin, K.E, Bell, S.G, Whelan, F. 登録日 2023-09-01 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.12 Å) 主引用文献 Structural insights into the S-lignin O-demethylase SyoA To Be Published
5C12	Nuclease domain of the large terminase subunit gp2 of bacterial virus Sf6 分子名称: Gene 2 protein, MAGNESIUM ION 著者 Zhao, H, Tang, L. 登録日 2015-06-12 公開日 2015-10-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.517 Å) 主引用文献 Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism. Nucleic Acids Res., 43, 2015
6MBI	Crystal Structure of SNX15 PX domain in domain swapped conformation form 2 分子名称: Sorting nexin-15 著者 Chandra, M, Collins, B.M. 登録日 2018-08-29 公開日 2018-09-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.834 Å) 主引用文献 Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities. Nat Commun, 10, 2019

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