PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

---

6YUM	CK2 alpha bound to unclosed Macrocycle 分子名称: 4-[5-[2-(2-hydroxyethyloxy)ethyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pyrazolo[1,5-a]pyrimidin-3-yl]-2-oxidanyl-benzoic acid, Casein kinase II subunit alpha, SULFATE ION 著者 Kraemer, A, Hanke, T, Kurz, C, Celik, I, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2020-04-27 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor. Eur.J.Med.Chem., 208, 2020
4YIK	Crystal structure of human cytosolic 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PVU 分子名称: 1-{2-deoxy-3,5-O-[phenyl(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-[(E)-2-phosphonoethenyl]pyrimidine-2,4(1H,3H)-dione, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'(3')-deoxyribonucleotidase, ... 著者 Pachl, P, Rezacova, P, Brynda, J. 登録日 2015-03-02 公開日 2015-09-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.483 Å) 主引用文献 Structure-based design of a bisphosphonate 5'(3')-deoxyribonucleotidase inhibitor Medchemcomm, 6, 2015
1N95	Aryl Tetrahydrophyridine Inhbitors of Farnesyltranferase: Glycine, Phenylalanine and Histidine Derivatives 分子名称: 1-[2-(4-CYANO-BENZYLAMINO)-3-(3-METHYL-3H-IMIDAZOL-4-YL)-PROPIONYL]-5-NAPHTHALEN-1-YL-1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ... 著者 Gwaltney II, S.L, O'Conner, S.J, Nelson, L.T, Sullivan, G.M, Imade, H, Wang, W, Hasvold, L, Li, Q, Cohen, J, Gu, W.Z. 登録日 2002-11-22 公開日 2003-01-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives. Bioorg.Med.Chem.Lett., 13, 2003
7ER3	Crystal structure of beta-lactoglobulin complexed with chloroquine 分子名称: (4S)-N~4~-(7-chloroquinolin-4-yl)-N~1~,N~1~-diethylpentane-1,4-diamine, Major allergen beta-lactoglobulin 著者 Yao, Q, Ma, J, Xing, Y, Zang, J. 登録日 2021-05-05 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.598 Å) 主引用文献 Binding of Chloroquine to Whey Protein Relieves Its Cytotoxicity while Enhancing Its Uptake by Cells. J.Agric.Food Chem., 69, 2021
6Z30	Human cation-independent mannose 6-phosphate/ IGF2 receptor domains 9-10 分子名称: Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Bochel, A.J, Williams, C, Crump, M.P. 登録日 2020-05-19 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9. Structure, 28, 2020
2W88	Plastocyanin variant with N-terminal Methionine - open structure 分子名称: COPPER (II) ION, PLASTOCYANIN, ZINC ION 著者 Crowley, P.B, Matias, P.M, Khan, A.R. 登録日 2009-01-14 公開日 2009-10-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Metal-Mediated Self-Assembly of a Beta-Sandwich Protein. Chemistry, 15, 2009
8AED	Broadly neutralizing DARPin bnD.9 in complex with the HIV-1 envelope variable loop 3 peptide V3 (BG505) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Broadly neutralizing DARPin bnD.9, ... 著者 Mittl, P, Gloegl, M. 登録日 2022-07-13 公開日 2023-08-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.17 Å) 主引用文献 Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization. Nat.Struct.Mol.Biol., 30, 2023
6ZIO	CRYSTAL STRUCTURE OF NRAS (C118S) IN COMPLEX WITH GDP 分子名称: GTPase NRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Kessler, D, Fischer, G, Boettcher, J. 登録日 2020-06-26 公開日 2020-08-19 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Drugging all RAS isoforms with one pocket. Future Med Chem, 12, 2020
4X7I	Crystal Structure of BACE with amino thiazine inhibitor LY2886721 分子名称: Beta-secretase 1, GLYCEROL, N-{3-[(4aS,7aS)-2-amino-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide 著者 Timm, D.E. 登録日 2014-12-09 公開日 2014-12-24 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The Potent BACE1 Inhibitor LY2886721 Elicits Robust Central A beta Pharmacodynamic Responses in Mice, Dogs, and Humans. J.Neurosci., 35, 2015
7BIJ	Crystal Structure of SARS-CoV-2 main protease (Nsp5) in complex with compound 13 分子名称: (3~{S})-3'-(5-fluoranylpyridin-3-yl)spiro[1,2-dihydroindene-3,5'-imidazolidine]-2',4'-dione, 3C-like proteinase nsp5, DIMETHYL SULFOXIDE 著者 Talibov, V.O. 登録日 2021-01-12 公開日 2022-02-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses. J.Am.Chem.Soc., 144, 2022
1OFF	2Fe-2S Ferredoxin from Synechocystis sp. PCC 6803 分子名称: FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN I 著者 Van Den heuvel, R.H.H, Mattevi, A. 登録日 2003-04-14 公開日 2003-06-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Active Conformation of Glutamate Synthase and its Binding to Ferredoxin J.Mol.Biol., 330, 2003
4X1U	The structure of AhpE from Mycobacterium tuberculosis revisited 分子名称: GLYCEROL, Putative peroxiredoxin MT2298 著者 Pallo, A, Messens, J. 登録日 2014-11-25 公開日 2016-07-27 最終更新日 2016-08-10 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Revisiting sulfur H-bonds in proteins: The example of peroxiredoxin AhpE. Sci Rep, 6, 2016
1OFD	Glutamate Synthase from Synechocystis sp in complex with 2-Oxoglutarate at 2.0 Angstrom resolution 分子名称: 2-OXOGLUTARIC ACID, FE3-S4 CLUSTER, FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE 2, ... 著者 Van Den heuvel, R.H.H, Mattevi, A. 登録日 2003-04-14 公開日 2003-06-11 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Active Conformation of Glutamate Synthase and its Binding to Ferredoxin J.Mol.Biol., 330, 2003
6Z9H	Escherichia coli D-2-deoxyribose-5-phosphate aldolase - C47V/G204A/S239D mutant 分子名称: 1,2-ETHANEDIOL, Deoxyribose-phosphate aldolase, FORMIC ACID, ... 著者 Paakkonen, J, Hakulinen, N, Rouvinen, J. 登録日 2020-06-04 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Substrate specificity of 2-deoxy-D-ribose 5-phosphate aldolase (DERA) assessed by different protein engineering and machine learning methods. Appl.Microbiol.Biotechnol., 104, 2020
6Z1V	Structure of the EC2 domain of CD9 in complex with nanobody 4E8 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CD9 antigen, ... 著者 Oosterheert, W, Pearce, N.M, Gros, P. 登録日 2020-05-14 公開日 2020-09-23 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F. Life Sci Alliance, 3, 2020
6Z20	Structure of the EC2 domain of CD9 in complex with nanobody 4C8 分子名称: CD9 antigen, CHLORIDE ION, GLYCEROL, ... 著者 Oosterheert, W, Manshande, J, Pearce, N.M, Lutz, M, Gros, P. 登録日 2020-05-14 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F. Life Sci Alliance, 3, 2020
6ZCV	Crystal structure of lanthanide-dependent alcohol dehydrogenase PedH from Pseudomonas putida KT2440 分子名称: CALCIUM ION, GLYCEROL, PRASEODYMIUM ION, ... 著者 Bange, G, Lepak, A, Elsayed, E.M. 登録日 2020-06-12 公開日 2020-07-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Engineered PQQ-Dependent Alcohol Dehydrogenase for the Oxidation of 5-(Hydroxymethyl)furoic Acid Acs Catalysis, 2020
6Z31	Human cation-independent mannose 6-phosphate/ IGF2 receptor domain 8 分子名称: CHLORIDE ION, Cation-independent mannose-6-phosphate receptor, SODIUM ION 著者 Bochel, A.J, Williams, C, Crump, M.P. 登録日 2020-05-19 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9. Structure, 28, 2020
5TUK	Crystal structure of tetracycline destructase Tet(51) 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Tetracycline destructase Tet(51) 著者 Park, J, Tolia, N.H. 登録日 2016-11-06 公開日 2017-05-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Plasticity, dynamics, and inhibition of emerging tetracycline resistance enzymes. Nat. Chem. Biol., 13, 2017
6ZJB	Crystal structure of human adenylate kinase 3, AK3, in complex with inhibitor Gp5A 分子名称: GTP:AMP phosphotransferase AK3, mitochondrial, MAGNESIUM ION, ... 著者 Grundstrom, C, Rogne, P, Wolf-Watz, M, Sauer-Eriksson, A.E. 登録日 2020-06-28 公開日 2020-09-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.822 Å) 主引用文献 Structural Basis for GTP versus ATP Selectivity in the NMP Kinase AK3. Biochemistry, 59, 2020
6Z7Z	Porcine insulin in complex with the analytical antibody OXI-005 Fab 分子名称: Insulin, MAGNESIUM ION, OXI-005 Fab Heavy chain, ... 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
4WPE	Crystal Structure of Hof1p F-BAR domain 分子名称: Cytokinesis protein 2 著者 Lemmon, M.A, Moravcevic, K. 登録日 2014-10-17 公開日 2014-12-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site. Structure, 23, 2015
6Z7W	Human insulin in complex with the analytical antibody HUI-018 Fab 分子名称: HUI-018 Fab Heavy Chain, Insulin, MAb 6H10 light chain 著者 Johansson, E. 登録日 2020-06-02 公開日 2020-12-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 Insulin binding to the analytical antibody sandwich pair OXI-005 and HUI-018: Epitope mapping and binding properties. Protein Sci., 30, 2021
4WX1	Structure of Aspergillus fumigatus UDP-Galactopyranose mutase mutant F66A determined from a crystal soaked with UDP-Galactopyranose 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, SULFATE ION, ... 著者 Qureshi, I.A, Chaudhary, R. 登録日 2014-11-13 公開日 2014-12-03 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Contributions of Unique Active Site Residues of Eukaryotic UDP-Galactopyranose Mutases to Substrate Recognition and Active Site Dynamics. Biochemistry, 53, 2014
2X52	CRYSTAL STRUCTURE OF WHEAT GERM AGGLUTININ ISOLECTIN 3 IN COMPLEX WITH A SYNTHETIC DIVALENT CARBOHYDRATE LIGAND 分子名称: AGGLUTININ ISOLECTIN 3, BIS-(2-ACETAMIDO-2-DEOXY-ALPHA-D-GLUCOPYRANOSYLOXYCARBONYL)-4,7,10-TRIOXA-1,13-TRIDECANEDIAMINE, GLYCEROL 著者 Schwefel, D, Maierhofer, C, Wittmann, V, Diederichs, K, Welte, W. 登録日 2010-02-05 公開日 2010-02-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis of Multivalent Binding to Wheat Germ Agglutinin. J.Am.Chem.Soc., 132, 2010

<526527528529530531532533534535536537538539540541>