6Z30

Human cation-independent mannose 6-phosphate/ IGF2 receptor domains 9-10

Summary for 6Z30

• Entry DOI: 10.2210/pdb6z30/pdb
• Descriptor: Cation-independent mannose-6-phosphate receptor, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: mannose 6-phosphate, cation-independent mannose 6-phosphate receptor, insulin-like growth factor 2 receptor, p-type lectin, sugar binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 34719.72

Authors

Bochel, A.J.,Williams, C.,Crump, M.P. (deposition date: 2020-05-19, release date: 2020-08-19, Last modification date: 2020-12-09)

• Primary citation: Bochel, A.J.,Williams, C.,McCoy, A.J.,Hoppe, H.J.,Winter, A.J.,Nicholls, R.D.,Harlos, K.,Jones, E.Y.,Berger, I.,Hassan, A.B.,Crump, M.P.; Structure of the Human Cation-Independent Mannose 6-Phosphate/IGF2 Receptor Domains 7-11 Uncovers the Mannose 6-Phosphate Binding Site of Domain 9.; Structure, 28:1300-1312.e5, 2020; PubMed: 32877646; DOI: 10.1016/j.str.2020.08.002

Experimental method

X-RAY DIFFRACTION (1.5 Å)