6Z30

Human cation-independent mannose 6-phosphate/ IGF2 receptor domains 9-10

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Cation-independent mannose-6-phosphate receptor	polymer	302	33646.8	1	UniProt (P11717) Pfam (PF00878) In PDB	Homo sapiens (Human)	M6PR,300 kDa mannose 6-phosphate receptor,MPR 300,Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor,IGF-II receptor,M6P/IGF2 receptor,M6P/IGF2R
2	B	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1073.0	1	In PDB GlyTouCan (G09724ZC)
3		water	water		18.0	439	Chemie (HOH)

Sequence modifications

A: 1222 - 1510 (UniProt: P11717)

PDB	External Database	Details
Glu 1217	-	expression tag
Thr 1218	-	expression tag
Gly 1219	-	expression tag
Ala 1220	-	expression tag
Ser 1221	-	expression tag
Thr 1511	-	expression tag
Arg 1512	-	expression tag
His 1513	-	expression tag
His 1514	-	expression tag
His 1515	-	expression tag
His 1516	-	expression tag
His 1517	-	expression tag
His 1518	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33646.8
Branched	Number of molecules	1
	Total formula weight	1073.0
All*	Total formula weight	34719.7

*Water molecules are not included.