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7DRT
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BU of 7drt by Molmil
Human Wntless in complex with Wnt3a
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-O-OCTADECYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Zhong, Q, Zhao, Y, Ye, F, Xiao, Z, Huang, G, Zhang, Y, Lu, P, Xu, W, Zhou, Q, Ma, D.
登録日2020-12-29
公開日2021-07-14
最終更新日2021-09-08
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Cryo-EM structure of human Wntless in complex with Wnt3a.
Nat Commun, 12, 2021
4GC6
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BU of 4gc6 by Molmil
Crystal structure of Dpo4 in complex with N-MC-dAMP opposite dT
分子名称: CALCIUM ION, DNA (5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*C)-3'), DNA (5'-D(*TP*CP*AP*TP*GP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), ...
著者Eoff, R.L, Ketkar, A, Banerjee, S, Zafar, M.K.
登録日2012-07-29
公開日2012-10-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.895 Å)
主引用文献Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues.
Biochemistry, 51, 2012
4FZJ
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BU of 4fzj by Molmil
Pantothenate synthetase in complex with 1,3-DIMETHYL-1H-THIENO[2,3-C]PYRAZOLE-5-CARBOXYLIC ACID
分子名称: 1,2-ETHANEDIOL, 1,3-dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid, ETHANOL, ...
著者Silvestre, H.L, Blundell, T.L, Abell, C, Ciulli, A.
登録日2012-07-06
公開日2013-06-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery.
Proc.Natl.Acad.Sci.USA, 110, 2013
7ZC7
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BU of 7zc7 by Molmil
Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941
分子名称: 2-[4-(3,5-dimethylpyrazol-1-yl)phenyl]-~{N}-(4,5,6,7-tetrahydro-1,2-benzoxazol-3-yl)ethanamide, N-glycosylase/DNA lyase, NICKEL (II) ION
著者Davies, J.R, Scaletti, E, Stenmark, P.
登録日2022-03-25
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH012941
To Be Published
4FZZ
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BU of 4fzz by Molmil
Exonuclease X in complex with 5' overhanging duplex DNA
分子名称: DNA (5'-D(*GP*TP*CP*AP*TP*TP*GP*TP*GP*GP*AP*TP*CP*CP*GP*AP*G)-3'), Exodeoxyribonuclease 10, SODIUM ION
著者Wang, T, Sun, H, Cheng, F, Bi, L, Jiang, T.
登録日2012-07-08
公開日2013-07-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Recognition and processing of double-stranded DNA by ExoX, a distributive 3'-5' exonuclease
Nucleic Acids Res., 41, 2013
5I4O
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BU of 5i4o by Molmil
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate zinc-chelator water-soluble inhibitor (DC28).
分子名称: CALCIUM ION, Macrophage metalloelastase, N-({1-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-1H-1,2,3-triazol-4-yl}methyl)-N-[([1,1'-biphenyl]-4-yl)sulfonyl]-D-valine, ...
著者Stura, E.A, Rosalia, L, Cuffaro, D, Tepshi, L, Ciccone, L, Rossello, A.
登録日2016-02-12
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors.
Chemmedchem, 11, 2016
2GFE
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BU of 2gfe by Molmil
Crystal structure of the GluR2 A476E S673D Ligand Binding Core Mutant at 1.54 Angstroms Resolution
分子名称: GLUTAMIC ACID, Glutamate receptor 2, ZINC ION
著者Mayer, M.L.
登録日2006-03-21
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Interdomain interactions in AMPA and kainate receptors regulate affinity for glutamate.
J.Neurosci., 26, 2006
4HQN
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BU of 4hqn by Molmil
Crystal structure of manganese-loaded Plasmodium vivax TRAP protein
分子名称: CHLORIDE ION, MANGANESE (II) ION, Sporozoite surface protein 2, ...
著者Song, G, Koksal, A.C, Lu, C, Springer, T.A.
登録日2012-10-25
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.196 Å)
主引用文献Shape change in the receptor for gliding motility in Plasmodium sporozoites.
Proc.Natl.Acad.Sci.USA, 109, 2012
7YW3
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BU of 7yw3 by Molmil
Crystal structure of tRNA 2'-phosphotransferase from Homo sapiens
分子名称: 1,2-ETHANEDIOL, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-3,4-bis(oxidanyl)-5-phosphonooxy-oxolan-2-yl]methyl hydrogen phosphate, tRNA 2'-phosphotransferase 1
著者Yang, X.Y, Liu, X.H.
登録日2022-08-21
公開日2023-07-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Nucleic Acids Res., 51, 2023
7YW4
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BU of 7yw4 by Molmil
Crystal structure of tRNA 2'-phosphotransferase from Saccharomyces cerevisiae
分子名称: D(-)-TARTARIC ACID, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, tRNA 2'-phosphotransferase
著者Yang, X.Y, Liu, X.H.
登録日2022-08-21
公開日2023-07-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Nucleic Acids Res., 51, 2023
2GAG
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BU of 2gag by Molmil
Heteroteterameric sarcosine: structure of a diflavin metaloenzyme at 1.85 a resolution
分子名称: 2-FUROIC ACID, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Chen, Z.W, Hassan-Abdulah, A, Zhao, G, Jorns, M.S, Mathews, F.S.
登録日2006-03-08
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Heterotetrameric sarcosine oxidase: structure of a diflavin metalloenzyme at 1.85 a resolution.
J.Mol.Biol., 360, 2006
7ZCB
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BU of 7zcb by Molmil
Human Pikachurin/EGFLAM N-terminal Fibronectin-III (1-2) domains
分子名称: CHLORIDE ION, Pikachurin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Pantalone, S, Savino, S, Viti, L.V, Forneris, F.
登録日2022-03-26
公開日2023-07-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.
Sci.Signal., 16, 2023
6LXN
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BU of 6lxn by Molmil
Crystal structure of C-terminal DNA-binding domain of Escherichia coli OmpR in complex with F1-DNA
分子名称: DNA (27-MER), SULFATE ION, Transcriptional regulatory protein OmpR
著者Sadotra, S, Chen, C, Hsu, C.H.
登録日2020-02-11
公開日2020-12-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Structural basis for promoter DNA recognition by the response regulator OmpR.
J.Struct.Biol., 213, 2020
2GB8
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BU of 2gb8 by Molmil
Solution structure of the complex between yeast iso-1-cytochrome c and yeast cytochrome c peroxidase
分子名称: Cytochrome c iso-1, Cytochrome c peroxidase, HEME C, ...
著者Volkov, A.N, Worrall, J.A.R, Ubbink, M.
登録日2006-03-10
公開日2006-11-21
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the complex between cytochrome c and cytochrome c peroxidase determined by paramagnetic NMR.
Proc.Natl.Acad.Sci.Usa, 103, 2006
5I23
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BU of 5i23 by Molmil
Crystal Structure of Agd31B, alpha-transglucosylase in Glycoside Hydrolase Family 31, in complex with Cyclophellitol Aziridine probe CF022
分子名称: 1,2-ETHANEDIOL, 1-(8-{[(1S,2R,3S,4S,5R,6R)-2,3,4,5-tetrahydroxy-6-(hydroxymethyl)cyclohexyl]amino}octyl)triaza-1,2-dien-2-ium, Oligosaccharide 4-alpha-D-glucosyltransferase, ...
著者Wu, L, Davies, G.J.
登録日2016-02-08
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Detection of Active Mammalian GH31 alpha-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes.
Acs Cent.Sci., 2, 2016
6LYJ
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BU of 6lyj by Molmil
The crystal structure of SAUGI/EBVUDG complex
分子名称: SAUGI, Uracil-DNA glycosylase
著者Liao, Y.T, Ko, T.P, Wang, H.C.
登録日2020-02-14
公開日2020-06-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insight into the differential interactions between the DNA mimic protein SAUGI and two gamma herpesvirus uracil-DNA glycosylases.
Int.J.Biol.Macromol., 160, 2020
7YW2
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BU of 7yw2 by Molmil
Crystal structure of tRNA 2'-phosphotransferase from Mus musculus
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, GLYCINE, ...
著者Yang, X.Y, Liu, X.H.
登録日2022-08-21
公開日2023-07-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural and biochemical insights into the molecular mechanism of TRPT1 for nucleic acid ADP-ribosylation.
Nucleic Acids Res., 51, 2023
2G2B
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BU of 2g2b by Molmil
NMR structure of the human allograft inflammatory factor 1
分子名称: Allograft inflammatory factor 1
著者Song, J, Tyler, R.C, Newman, C.L, Vinarov, D, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-02-15
公開日2006-02-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献NMR structure of the human allograft inflammatory factor 1
To be published
7YNQ
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BU of 7ynq by Molmil
PiB-bound alpha-synuclein fibrils conformation 2
分子名称: 2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献PiB-bound alpha-synuclein fibrils conformation 2
To Be Published
2GE5
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BU of 2ge5 by Molmil
EcoRV Restriction Endonuclease C-terminal deletion mutant/GATATC/Ca2+
分子名称: 5'-D(*AP*AP*AP*GP*AP*TP*AP*TP*CP*TP*T)-3', CALCIUM ION, Type II restriction enzyme EcoRV
著者Hiller, D.A, Perona, J.J.
登録日2006-03-17
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Positively Charged C-Terminal Subdomains of EcoRV Endonuclease: Contributions to DNA Binding, Bending, and Cleavage.
Biochemistry, 45, 2006
7DEG
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BU of 7deg by Molmil
Cryo-EM structure of a heme-copper terminal oxidase dimer provides insights into its catalytic mechanism
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-[(2~{E},6~{E},10~{Z},14~{Z},18~{Z},23~{R})-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18-pentaenyl]naphthalene-1,4-dione, ...
著者Fei, S, Hartmut, M, Yun, Z, Guoliang, Z, Shuangbo, Z.
登録日2020-11-04
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献The Unusual Homodimer of a Heme-Copper Terminal Oxidase Allows Itself to Utilize Two Electron Donors.
Angew.Chem.Int.Ed.Engl., 60, 2021
6LPC
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BU of 6lpc by Molmil
Crystal Structure of rat Munc18-1 with K332E/K333E mutation
分子名称: Syntaxin-binding protein 1
著者Wang, X.P, Gong, J.H, Wang, S, Zhu, L, Yang, X.Y, Xu, Y.Y, Yang, X.F, Ma, C.
登録日2020-01-09
公開日2020-07-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.402 Å)
主引用文献Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assembly.
Embo J., 39, 2020
7YNT
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BU of 7ynt by Molmil
pFTAA-bound alpha-synuclein fibrils
分子名称: Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献pFTAA-bound alpha-synuclein fibrils
To Be Published
7YNM
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BU of 7ynm by Molmil
ThT-bound alpha-synuclein fibrils conformation 1
分子名称: 2-[4-(dimethylamino)phenyl]-3,6-dimethyl-1,3-benzothiazol-3-ium, Alpha-synuclein
著者Tao, Y.Q, Zhao, Q.Y, Liu, C, Li, D.
登録日2022-07-31
公開日2023-08-02
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献ThT-bound alpha-synuclein fibrils conformation 1
To Be Published
4L5I
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BU of 4l5i by Molmil
Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition
分子名称: Transcriptional regulator LsrR
著者Ryu, K.S, Ha, J.H, Eo, Y.
登録日2013-06-11
公開日2013-11-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition.
J.Am.Chem.Soc., 135, 2013

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