6LPC

Crystal Structure of rat Munc18-1 with K332E/K333E mutation

Summary for 6LPC

• Entry DOI: 10.2210/pdb6lpc/pdb
• Descriptor: Syntaxin-binding protein 1 (1 entity in total)
• Functional Keywords: synaptic exocytosis, membrane fusion, snares-binding, exocytosis
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 2
• Total formula weight: 135331.14

Authors

Wang, X.P.,Gong, J.H.,Wang, S.,Zhu, L.,Yang, X.Y.,Xu, Y.Y.,Yang, X.F.,Ma, C. (deposition date: 2020-01-09, release date: 2020-07-15, Last modification date: 2023-11-29)

• Primary citation: Wang, X.,Gong, J.,Zhu, L.,Wang, S.,Yang, X.,Xu, Y.,Yang, X.,Ma, C.; Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assembly.; Embo J., 39:e103631-e103631, 2020; PubMed: 32643828; DOI: 10.15252/embj.2019103631

Experimental method

X-RAY DIFFRACTION (3.402 Å)