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8VFO
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BU of 8vfo by Molmil
Crystal Structure of L117G Variant of D-Dopachrome Tautomerase (D-DT)
分子名称: CITRIC ACID, D-dopachrome decarboxylase
著者Parkins, A, Pilien, A, Thompson, M.C, Pantouris, G.
登録日2023-12-21
公開日2024-05-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献The C-terminal Region of D-DT Regulates Molecular Recognition for Protein-Ligand Complexes.
J.Med.Chem., 67, 2024
8XF2
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BU of 8xf2 by Molmil
Crystal structure of the reassembled C-phycocyanin hexamer from Thermoleptolyngbya sp. O-77
分子名称: C-phycocyanin alpha chain, C-phycocyanin beta chain, PHOSPHATE ION, ...
著者Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S.
登録日2023-12-13
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
8XEJ
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BU of 8xej by Molmil
Cryo-EM structure of human XKR8-basigin complex in lipid nanodisc
分子名称: 1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab heavy chain, Fab light chain, ...
著者Sakuragi, T.S, Kanai, R.K, Kikkawa, M.K, Toyoshima, C.T, Nagata, S.N.
登録日2023-12-12
公開日2024-02-28
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献The role of the C-terminal tail region as a plug to regulate XKR8 lipid scramblase.
J.Biol.Chem., 300, 2024
8XF0
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BU of 8xf0 by Molmil
Crystal structure of the dissociated C-phycocyanin alpha-chain from Thermoleptolyngbya sp. O-77
分子名称: C-phycocyanin alpha chain, MAGNESIUM ION, PHYCOCYANOBILIN
著者Nguyen, H.K, Teramoto, T, Kakuta, Y, Yoon, K.S.
登録日2023-12-13
公開日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Disassembly and reassembly of the non-conventional thermophilic C-phycocyanin.
J.Biosci.Bioeng., 137, 2024
6OSJ
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BU of 6osj by Molmil
Cryo-EM structure of the N-terminally acetylated full length alpha-synuclein fibrils (Ac1-140)
分子名称: Alpha-synuclein
著者Xiaodan, N, Ryan, P.M, Jiansen, J, Jennifer, C.L.
登録日2019-05-01
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural Insights into alpha-Synuclein Fibril Polymorphism: Effects of Parkinson's Disease-Related C-Terminal Truncations.
J.Mol.Biol., 431, 2019
6V59
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BU of 6v59 by Molmil
Crystal structure of the diheme peroxidase BthA Y463M variant from Burkholderia thailandensis E264
分子名称: CHLORIDE ION, Di-haem cytochrome c peroxidase family protein, GLYCEROL, ...
著者Cohen, S.E, Drennan, C.L.
登録日2019-12-03
公開日2020-07-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.593 Å)
主引用文献A Stable Ferryl Porphyrin at the Active Site of Y463M BthA.
J.Am.Chem.Soc., 142, 2020
7ST8
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BU of 7st8 by Molmil
Crystal structure of 7H2.2 Fab in complex with SAS1B C-terminal region
分子名称: 7H2.2 Fab Heavy Chain, 7H2.2 Fab Light Chain, Astacin-like metalloendopeptidase
著者Legg, M.S.G, Evans, S.V.
登録日2021-11-12
公開日2022-05-11
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Monoclonal antibody 7H2.2 binds the C-terminus of the cancer-oocyte antigen SAS1B through the hydrophilic face of a conserved amphipathic helix corresponding to one of only two regions predicted to be ordered
Acta Crystallogr.,Sect.D, 78, 2022
6Y2M
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BU of 6y2m by Molmil
Streptavidin mutant S112R with a biotC4-1 cofactor - an artificial iron hydroxylase
分子名称: Streptavidin, biotC4-1 cofactor
著者Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R.
登録日2020-02-17
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology.
J.Am.Chem.Soc., 142, 2020
6Y2T
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BU of 6y2t by Molmil
Streptavidin wildtype with a biotC4-1 cofactor - an artificial iron hydroxylase
分子名称: GLYCEROL, Streptavidin, biotC4-1 cofactor
著者Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R.
登録日2020-02-17
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology.
J.Am.Chem.Soc., 142, 2020
6Y3Q
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BU of 6y3q by Molmil
Streptavidin mutant S112R_K121E with a biotC5-1 cofactor - an artificial iron hydroxylase
分子名称: SULFATE ION, Streptavidin, biotC5-1 cofactor
著者Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R.
登録日2020-02-18
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology.
J.Am.Chem.Soc., 142, 2020
6Y25
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BU of 6y25 by Molmil
Streptavidin mutant S112R,K121E with a biotC4-1 cofactor - an artificial iron hydroxylase
分子名称: Streptavidin, biotC4-1 cofactor
著者Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R.
登録日2020-02-14
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology.
J.Am.Chem.Soc., 142, 2020
6Y34
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BU of 6y34 by Molmil
Streptavidin wildtype with a biotC5-1 cofactor - an artificial iron hydroxylase
分子名称: GLYCEROL, Streptavidin, biotC5-1 cofactor
著者Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R.
登録日2020-02-17
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.307 Å)
主引用文献Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology.
J.Am.Chem.Soc., 142, 2020
8AN8
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BU of 8an8 by Molmil
Crystal structure of wild-type c-MET bound by compound 7.
分子名称: 3-[bis(fluoranyl)methyl]-~{N}-methyl-~{N}-[(1~{R})-8-methyl-5-(3-methyl-1~{H}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide, Hepatocyte growth factor receptor, SULFATE ION
著者Collie, G.W.
登録日2022-08-04
公開日2022-08-31
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Discovery of a selective c-MET inhibitor with a novel binding mode.
Bioorg.Med.Chem.Lett., 75, 2022
8ANS
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BU of 8ans by Molmil
Crystal structure of D1228V c-MET bound by compound 1.
分子名称: 3-[bis(fluoranyl)methyl]-~{N}-methyl-~{N}-[(1~{R})-8-methyl-5-(3-methyl-1~{H}-indazol-6-yl)-1,2,3,4-tetrahydronaphthalen-1-yl]pyridine-2-carboxamide, GLYCEROL, Hepatocyte growth factor receptor
著者Collie, G.W.
登録日2022-08-05
公開日2022-08-31
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Discovery of a selective c-MET inhibitor with a novel binding mode.
Bioorg.Med.Chem.Lett., 75, 2022
6TNT
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BU of 6tnt by Molmil
SUMOylated apoAPC/C with repositioned APC2 WHB domain
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Barford, D, Yatskevich, S.
登録日2019-12-10
公開日2021-01-13
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.
Cell Rep, 34, 2021
1FCD
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BU of 1fcd by Molmil
THE STRUCTURE OF FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE FROM A PURPLE PHOTOTROPHIC BACTERIUM CHROMATIUM VINOSUM AT 2.5 ANGSTROMS RESOLUTION
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (CYTOCHROME SUBUNIT), FLAVOCYTOCHROME C SULFIDE DEHYDROGENASE (FLAVIN-BINDING SUBUNIT), ...
著者Chen, Z.W, Koh, M, Van Driessche, G, Van Beeumen, J.J, Bartsch, R.G, Meyer, T.E, Cusanovich, M.A, Mathews, F.S.
登録日1994-08-18
公開日1994-11-01
最終更新日2021-03-10
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium.
Science, 266, 1994
8DQW
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BU of 8dqw by Molmil
Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction
分子名称: DDC1 isoform 1, DNA (5'-D(P*CP*GP*TP*CP*CP*CP*TP*TP*CP*C)-3'), DNA (50-MER), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8AP5
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BU of 8ap5 by Molmil
Cadmium-loaded form of Caenorhabditis elegans MTL-2
分子名称: CADMIUM ION, Metallothionein-2
著者Leszczyszyn, O.I, Sturzenbaum, S.R, Blindauer, C.A.
登録日2022-08-09
公開日2024-01-17
実験手法SOLUTION NMR
主引用文献Juggling cadmium detoxification and zinc homeostasis: A division of labour between the two C. elegans metallothioneins.
Chemosphere, 350, 2023
8AQ9
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BU of 8aq9 by Molmil
Domain 2 of zinc-loaded Caenorhabditis elegans MTL-1
分子名称: Metallothionein-1, ZINC ION
著者Leszczyszyn, O.I, Sturzenbaum, S.R, Blindauer, C.A.
登録日2022-08-11
公開日2024-01-17
実験手法SOLUTION NMR
主引用文献Juggling cadmium detoxification and zinc homeostasis: A division of labour between the two C. elegans metallothioneins.
Chemosphere, 350, 2023
6NSV
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BU of 6nsv by Molmil
Crystal structure of the human CHIP TPR domain in complex with a 5mer acetylated optimized peptide
分子名称: ACE-LEU-TRP-TRP-PRO-ASP, CHLORIDE ION, E3 ubiquitin-protein ligase CHIP, ...
著者Basu, K, Ravalin, M, Bohn, M.-F, Craik, C.S, Gestwicki, J.E.
登録日2019-01-25
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.305 Å)
主引用文献Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.
Nat.Chem.Biol., 15, 2019
8FX4
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BU of 8fx4 by Molmil
GC-C-Hsp90-Cdc37 regulatory complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Guanylyl cyclase C, Heat shock protein HSP 90-beta, ...
著者Caveney, N.A, Garcia, K.C.
登録日2023-01-23
公開日2023-07-12
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insight into guanylyl cyclase receptor hijacking of the kinase-Hsp90 regulatory mechanism.
Elife, 12, 2023
1G96
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BU of 1g96 by Molmil
HUMAN CYSTATIN C; DIMERIC FORM WITH 3D DOMAIN SWAPPING
分子名称: CHLORIDE ION, CYSTATIN C, GLYCEROL
著者Janowski, R, Kozak, M, Jankowska, E, Grzonka, Z, Grubb, A, Abrahamson, M, Jaskolski, M.
登録日2000-11-22
公開日2001-04-06
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping.
Nat.Struct.Biol., 8, 2001
5KLI
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BU of 5kli by Molmil
Rhodobacter sphaeroides bc1 with stigmatellin and antimycin
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (2R,3S,6S,7R,8R)-3-{[3-(FORMYLAMINO)-2-HYDROXYBENZOYL]AMINO}-8-HEXYL-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL (2S)-2-METHYLBUTANOATE, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-24
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
1GMI
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BU of 1gmi by Molmil
Structure of the c2 domain from novel protein kinase C epsilon
分子名称: MAGNESIUM ION, PROTEIN KINASE C, EPSILON TYPE
著者Ochoa, W.F, Garcia-Garcia, J, Fita, I, Corbalan-Garcia, S, Verdaguer, N, Gomez-Fernandez, J.C.
登録日2001-09-14
公開日2001-10-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the C2 Domain from Novel Protein Kinase Cepsilon. A Membrane Binding Model for Ca(2+ )-Independent C2 Domains
J.Mol.Biol., 311, 2001
6Y33
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BU of 6y33 by Molmil
Streptavidin mutant S112R with a biotC5-1 cofactor - an artificial iron hydroxylase
分子名称: GLYCEROL, Streptavidin, biotC5-1 cofactor
著者Serrano-Plana, J, Rumo, C, Rebelein, J.G, Peterson, R.L, Barnet, M, Ward, T.R.
登録日2020-02-17
公開日2020-07-01
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Enantioselective Hydroxylation of Benzylic C(sp3)-H Bonds by an Artificial Iron Hydroxylase Based on the Biotin-Streptavidin Technology.
J.Am.Chem.Soc., 142, 2020

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