PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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7MP7	Rules for designing protein fold switches and their implications for the folding code 分子名称: Sb3 著者 He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. 登録日 2021-05-04 公開日 2022-05-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
7MN1	Rules for designing protein fold switches and their implications for the folding code 分子名称: Sa1 著者 He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. 登録日 2021-04-30 公開日 2022-05-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
7MQ4	Rules for designing protein fold switches and their implications for the folding code 分子名称: Sb1 著者 He, Y, Chen, Y, Ruan, B, Choi, J, Chen, Y, Motabar, D, Solomon, T, Simmerman, R, Kauffman, T, Gallagher, T, Bryan, P, Orban, J. 登録日 2021-05-05 公開日 2022-05-18 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Design and characterization of a protein fold switching network. Nat Commun, 14, 2023
5HHD	Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21 分子名称: D-Peptide RFX037.D, D-Vascular endothelial growth factor, DI(HYDROXYETHYL)ETHER, ... 著者 Uppalapati, M, LEE, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. 登録日 2016-01-10 公開日 2016-03-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. Acs Chem.Biol., 11, 2016
8UTK	IL-23R minibinder - 23R-B04dslf02IB 分子名称: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 23R-B04dslf02IB, ... 著者 Bera, A.K, Berger, S.A, Kang, A, Baker, D. 登録日 2023-10-31 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell, 2024
4UOT	Thermodynamic hyperstability in parametrically designed helical bundles 分子名称: DESIGNED HELICAL BUNDLE 5H2L 著者 Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. 登録日 2014-06-09 公開日 2014-11-05 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 High Thermodynamic Stability of Parametrically Designed Helical Bundles Science, 346, 2014
4UOS	Thermodynamic hyperstability in parametrically designed helical bundles 分子名称: DESIGNED HELICAL BUNDLE 著者 Oberdorfer, G, Huang, P, Pei, X.Y, Xu, C, Gonen, T, Nannenga, B, DiMaio, D, Rogers, J, Luisi, B.F, Baker, D. 登録日 2014-06-09 公開日 2014-11-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 High Thermodynamic Stability of Parametrically Designed Helical Bundles Science, 346, 2014
8TL7	CryoEM Structure of a Computationally Designed T3 Tetrahedral Nanocage 分子名称: Computationally designed protein 著者 Weidle, C, Borst, A.J. 登録日 2023-07-26 公開日 2024-03-13 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 Blueprinting extendable nanomaterials with standardized protein blocks. Nature, 627, 2024
4PQ8	Crystal Structure of Engineered Protein, Northeast Structural Genomics Consortium Target OR465 分子名称: CHLORIDE ION, DESIGNED PROTEIN OR465 著者 Vorobiev, S, Parmeggiani, F, Seetharaman, J, Janjua, H, Xiao, R, Maglaqui, M, Park, K, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J, Northeast Structural Genomics Consortium (NESG) 登録日 2014-02-28 公開日 2014-03-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.833 Å) 主引用文献 Crystal Structure of Engineered Protein OR465. To be Published
8V9O	Imaging scaffold engineered to bind the therapeutic protein target BARD1 分子名称: CALCIUM ION, Tetrahedral Nanocage Cage Component Fused to Anti-BARD1 Darpin, Tetrahedral Nanocage Cage, ... 著者 Agdanowski, M.P, Castells-Graells, R, Sawaya, M.R, Yeates, T.O, Arbing, M.A. 登録日 2023-12-08 公開日 2024-05-15 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (3.81 Å) 主引用文献 X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta Crystallogr.,Sect.F, 80, 2024
8VE7	A DARPin displayed on a designed tetrahedral protein scaffold 分子名称: DARPin protein scaffold 著者 Suder, D.S, Gonen, S. 登録日 2023-12-18 公開日 2024-06-05 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Mitigating the Blurring Effect of CryoEM Averaging on a Flexible and Highly Symmetric Protein Complex through Sub-Particle Reconstruction. Int J Mol Sci, 25, 2024
4R6F	Crystal structure of computational designed protein DLRR_I 分子名称: Leucine rich repeat DLRR_I 著者 Shen, B.W, Stoddard, B.L. 登録日 2014-08-25 公開日 2015-01-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Control of repeat-protein curvature by computational protein design. Nat.Struct.Mol.Biol., 22, 2015
5KAY	Structure of Spelter bound to Zn2+ 分子名称: SODIUM ION, Spelter, ZINC ION 著者 Guffy, S.L, Der, B.S, Kuhlman, B. 登録日 2016-06-02 公開日 2016-08-03 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Probing the minimal determinants of zinc binding with computational protein design. Protein Eng.Des.Sel., 29, 2016
6VEH	Computationally designed C3-symmetric homotrimer from HEAT repeat protein 分子名称: HEAT repeat domain-containing protein 著者 Bick, M.J, Ueda, G, Baker, D. 登録日 2020-01-02 公開日 2020-08-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. Elife, 9, 2020
6Y7N	The crystal structure of the eight-bladed symmetrical designer protein Tako8 in the presence of tellurotungstic Anderson-Evans (TEW) 分子名称: Tako8 著者 Vandebroek, L, Noguchi, H, Parac-Vogt, T.N, Van Meervelt, L, Voet, A.R.D. 登録日 2020-03-02 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Shape and Size Complementarity-Induced Formation of Supramolecular Protein Assemblies with Metal-Oxo Clusters Cryst.Growth Des., 2021
6Y7P	The complex between the eight-bladed symmetrical designer protein Tako8 and 1:2 zirconium(IV) Wells-Dawson (ZrWD) 分子名称: Tako8, W-Zr-cluster 著者 Vandebroek, L, Noguchi, H, Parac-Vogt, T.N, Van Meervelt, L, Voet, A.R.D. 登録日 2020-03-02 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Shape and Size Complementarity-Induced Formation of Supramolecular Protein Assemblies with Metal-Oxo Clusters Cryst.Growth Des., 2021
6Y7O	The complex between the eight-bladed symmetrical designer protein Tako8 and the silicotungstic acid Keggin (STA) 分子名称: Keggin (STA), Tako8 著者 Vandebroek, L, Noguchi, H, Parac-Vogt, T.N, Van Meervelt, L, Voet, A.R.D. 登録日 2020-03-02 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Shape and Size Complementarity-Induced Formation of Supramolecular Protein Assemblies with Metal-Oxo Clusters Cryst.Growth Des., 2021
6N4N	Crystal structure of the designed protein DNCR2/danoprevir/NS3a complex 分子名称: (2R,6S,12Z,13aS,14aR,16aS)-6-[(tert-butoxycarbonyl)amino]-14a-[(cyclopropylsulfonyl)carbamoyl]-5,16-dioxo-1,2,3,5,6,7,8 ,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclopropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-2-yl 4-fluoro-2H-isoindole-2-carboxylate, NS3 protease, Rosetta-designed danoprevir/NS3a complex reader 2, ... 著者 Wang, Z, Foight, G.W, Baker, D, Maly, D.J. 登録日 2018-11-19 公開日 2019-09-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Multi-input chemical control of protein dimerization for programming graded cellular responses. Nat.Biotechnol., 37, 2019
5IEP	Structure of CDL2.3b, a computationally designed Vitamin-D3 binder 分子名称: 3-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANOL, CDL2.3b 著者 Stoddard, B.L, Doyle, L.A. 登録日 2016-02-25 公開日 2017-03-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.893 Å) 主引用文献 Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold. Protein Eng.Des.Sel., 31, 2018
7KUW	High-throughput design and refinement of stable proteins using sequence-only models 分子名称: Sequence-Based Designed Protein nmt_0994_guided_02 著者 Bera, A.K, Stewart, L, Kang, A.S, Baker, D. 登録日 2020-11-25 公開日 2021-12-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Large-scale design and refinement of stable proteins using sequence-only models. Plos One, 17, 2022
5VL4	Accidental minimum contact crystal lattice formed by a redesigned protein oligomer 分子名称: T33-53H-B 著者 Cannon, K.A, Cascio, D, Sawaya, M.R, Park, R, Boyken, S, King, N, Yeates, T. 登録日 2017-04-24 公開日 2018-05-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Design and structure of two new protein cages illustrate successes and ongoing challenges in protein engineering. Protein Sci., 29, 2020
5HHC	Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21/n 分子名称: D- Vascular endothelial growth factor-A, GLYCEROL, Vascular endothelial growth factor A 著者 Uppalapati, M, Lee, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. 登録日 2016-01-10 公開日 2016-03-09 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. Acs Chem.Biol., 11, 2016
8T6C	Crystal structure of T33-18.2: Deep-learning sequence design of co-assembling tetrahedron protein nanoparticles 分子名称: T33-18.2 : A, T33-18.2 : B 著者 Bera, A.K, de Haas, R.J, Kang, A, Sankaran, B, King, N.P. 登録日 2023-06-15 公開日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Rapid and automated design of two-component protein nanomaterials using ProteinMPNN. Proc.Natl.Acad.Sci.USA, 121, 2024
1N09	A minimal beta-hairpin peptide scaffold for beta-turn display 分子名称: bhpW, disulfide cyclized beta-hairpin peptide 著者 Russell, S.J, Blandl, T, Skelton, N.J, Cochran, A.G. 登録日 2002-10-11 公開日 2003-02-04 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Stability of cyclic beta-hairpins: asymmetric contributions from side chains of a hydrogen-bonded cross-strand residue pair J.Am.Chem.Soc., 125, 2003
1N0D	Stability of cyclic beta-hairpins: Asymmetric contibutions from side chains of hydrogen bonded cross-strand residue pair 分子名称: bhp_VWLH, disulfide cyclized beta-hairpin peptide 著者 Russell, S.J, Blandl, T, Skelton, N.J, Cochran, A.G. 登録日 2002-10-11 公開日 2003-02-04 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Stability of Cyclic Beta-Hairpins: Asymmetric Contributions From Side Chains of Hydrogen Bonded Cross-Strand Residue Pair J.Am.Chem.Soc., 125, 2003

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