PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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7ZR0	CryoEM structure of HSP90-CDC37-BRAF(V600E) complex. 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-14 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
8A01	Bacteriophage phiCjT23 major capsid protein trimer type 1 分子名称: Major capsid protein P5 著者 Rissanen, I, Kejzar, N, Huiskonen, J.T. 登録日 2022-05-26 公開日 2022-12-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
8A04	Bacteriophage phiCjT23 major capsid protein trimer type 4 分子名称: Major capsid protein P5 著者 Rissanen, I, Kejzar, N, Huiskonen, J.T. 登録日 2022-05-26 公開日 2022-12-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
8A03	Bacteriophage phiCjT23 major capsid protein trimer type 3 分子名称: Major capsid protein P5 著者 Rissanen, I, Kejzar, N, Huiskonen, J.T. 登録日 2022-05-26 公開日 2022-12-14 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of ssDNA bacteriophage Phi CjT23 provides insight into early virus evolution. Nat Commun, 13, 2022
8A8R	Crystal structure of TEAD4 in complex with YAP peptide 分子名称: Isoform 7 of Transcriptional coactivator YAP1, MYRISTIC ACID, Transcriptional enhancer factor TEF-3 著者 Scheufler, C, Kallen, J. 登録日 2022-06-23 公開日 2022-12-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.696 Å) 主引用文献 N-terminal beta-strand in YAP is critical for stronger binding to scalloped relative to TEAD transcription factor. Protein Sci., 32, 2023
183L	SPECIFICITY OF LIGAND BINDING IN A BURIED NON-POLAR CAVITY OF T4 LYSOZYME: LINKAGE OF DYNAMICS AND STRUCTURAL PLASTICITY 分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, INDENE, ... 著者 Morton, A, Matthews, B.W. 登録日 1995-04-19 公開日 1995-07-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Specificity of ligand binding in a buried nonpolar cavity of T4 lysozyme: linkage of dynamics and structural plasticity. Biochemistry, 34, 1995
1N9A	Farnesyltransferase complex with tetrahydropyridine inhibitors 分子名称: 1-{2-[3-(4-CYANO-BENZYL)-3H-IMIDAZOL-4-YL]-ACETYL}-5-NAPHTHALEN-1-YL-1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBONITRILE, ALPHA-HYDROXYFARNESYLPHOSPHONIC ACID, Protein farnesyltransferase alpha subunit, ... 著者 Gwaltney II, S.L, O'Conner, S.J, Nelson, L.T, Sullivan, G.M, Imade, H, Wang, W, Hasvold, L, Li, Q, Cohen, J, Gu, W.Z. 登録日 2002-11-22 公開日 2003-01-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Aryl tetrahydropyridine inhibitors of farnesyltransferase: bioavailable analogues with improved cellular potency. Bioorg.Med.Chem.Lett., 13, 2003
8A8Q	Crystal structure of Protein Scalloped in complex with YAP peptide 分子名称: ACETATE ION, Isoform 7 of Transcriptional coactivator YAP1, Protein scalloped 著者 Scheufler, C, Villard, F. 登録日 2022-06-23 公開日 2022-12-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.465 Å) 主引用文献 N-terminal beta-strand in YAP is critical for stronger binding to scalloped relative to TEAD transcription factor. Protein Sci., 32, 2023
7ZQY	Chaetomium thermophilum Rad50 Zn hook 分子名称: DH domain-containing protein, ZINC ION 著者 Lammens, K, Rotheneder, M, Stakyte, K. 登録日 2022-05-03 公開日 2022-12-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
7ZR6	CryoEM structure of HSP90-CDC37-BRAF(V600E)-PP5(open) complex 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, Hsp90 co-chaperone Cdc37, ... 著者 Oberoi, J, Pearl, L.H. 登録日 2022-05-03 公開日 2022-12-28 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. Nat Commun, 13, 2022
7ZR1	Chaetomium thermophilum Mre11-Rad50-Nbs1 complex bound to ATPyS (composite structure) 分子名称: DH domain-containing protein, Double-strand break repair protein, FHA domain-containing protein, ... 著者 Bartho, J.D, Rotheneder, M, Stakyte, K, Lammens, K, Hopfner, K.P. 登録日 2022-05-03 公開日 2023-01-11 最終更新日 2023-12-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions. Mol.Cell, 83, 2023
1WUT	Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes 分子名称: 7-[2,6-DICHLORO-4-({[(2-CHLOROBENZOYL)AMINO]CARBONYL}AMINO)PHENOXY]HEPTANOIC ACID, Glycogen phosphorylase, muscle form, ... 著者 Klabunde, T, Wendt, K.U, Kadereit, D, Brachvogel, V, Burger, H.-J, Herling, A.W, Oikonomakos, N.G, Kosmopoulou, M.N, Schmoll, D, Sarubbi, E, von Roedern, E, Schonafinger, K, Defossa, E. 登録日 2004-12-08 公開日 2005-12-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Crystallographic studies on acyl ureas, a new class of glycogen phosphorylase inhibitors, as potential antidiabetic drugs Protein Sci., 14, 2005
3IIY	Crystal structure of Eed in complex with a trimethylated histone H1K26 peptide 分子名称: Histone H1K26 peptide, Polycomb protein EED 著者 Justin, N, Sharpe, M.L, Martin, S, Taylor, W.R, De Marco, V, Gamblin, S.J. 登録日 2009-08-03 公開日 2009-09-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Role of the polycomb protein EED in the propagation of repressive histone marks. Nature, 461, 2009
3IML	Crystal Structure Of S-Adenosylmethionine Synthetase From Burkholderia Pseudomallei 分子名称: S-adenosylmethionine synthetase 著者 Staker, B.L, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-08-10 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
8A16	Human PTPRM domains FN3-4, in spacegroup P212121 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Caroe, E, Graham, S.C, Sharpe, H.J, Deane, J.E. 登録日 2022-05-31 公開日 2023-03-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.89 Å) 主引用文献 Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
8A1F	Human PTPRK N-terminal domains MAM-Ig-FN1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Hay, I.M, Graham, S.C, Sharpe, H.J, Deane, J.E. 登録日 2022-06-01 公開日 2023-03-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
8A17	Human PTPRM domains FN3-4, in spacegroup P3221 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-type tyrosine-protein phosphatase mu, ... 著者 Shamin, M, Graham, S.C, Sharpe, H.J, Deane, J.E. 登録日 2022-05-31 公開日 2023-03-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.09 Å) 主引用文献 Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains. J.Biol.Chem., 299, 2023
4XI1	Crystal structure of U-box 2 of LubX / LegU2 / Lpp2887 from Legionella pneumophila str. Paris, wild-type 分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase LubX, GLYCEROL, ... 著者 Stogios, P.J, Quaile, T, Skarina, T, Cuff, M, Di Leo, R, Yim, V, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2015-01-06 公開日 2015-01-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.983 Å) 主引用文献 Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila. Structure, 23, 2015
4XGU	Structure of C. elegans PCH-2 分子名称: ADENOSINE-5'-DIPHOSPHATE, Putative pachytene checkpoint protein 2, SULFATE ION 著者 Ye, Q, Corbett, K.D. 登録日 2015-01-02 公開日 2015-05-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. Elife, 4, 2015
4XKX	Crystal structure of BACE1 in complex with 2-aminooxazoline 3-azaxanthene inhibitor 28 分子名称: (5S)-7-(2-fluoropyridin-3-yl)-3-(2-fluoropyridin-4-yl)spiro[chromeno[2,3-c]pyridine-5,4'-[1,3]oxazol]-2'-amine, Beta-secretase 1, GLYCEROL, ... 著者 Whittington, D.A, Long, A.M. 登録日 2015-01-12 公開日 2015-02-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious beta-secretase inhibitors for the potential treatment of Alzheimer's disease. Bioorg.Med.Chem.Lett., 25, 2015
4XL8	Crystal Structure of Human Adenovirus 52 Short Fiber Knob in Complex with 2-O-Methyl-5-N-Acetylneuraminic Acid 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-O-methyl-5-N-acetyl-alpha-D-neuraminic acid, ... 著者 Stehle, T, Liaci, A.M. 登録日 2015-01-13 公開日 2015-01-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Human Adenovirus 52 Uses Sialic Acid-containing Glycoproteins and the Coxsackie and Adenovirus Receptor for Binding to Target Cells. Plos Pathog., 11, 2015
3I9G	Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate 分子名称: (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, CALCIUM ION, MAGNESIUM ION, ... 著者 Huxford, T. 登録日 2009-07-10 公開日 2009-09-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen. Proc.Natl.Acad.Sci.USA, 106, 2009
3VZ7	Crystal Structure Analysis of the mini-chaperonin variant with Pro 187 Gly 分子名称: 60 kDa chaperonin 著者 Saijo, S, Sato, T. 登録日 2012-10-09 公開日 2013-11-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Binding Energy(BE) from Crystal Packing of Mini-chaperones (mcpn) Provided Insights into the Allosteric Interaction of GroEL/ES Complex To be Published
1O63	Crystal structure of an ATP phosphoribosyltransferase 分子名称: ATP phosphoribosyltransferase 著者 Structural GenomiX 登録日 2003-10-23 公開日 2003-11-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005
1O6C	Crystal structure of UDP-N-acetylglucosamine 2-epimerase 分子名称: UDP-N-acetylglucosamine 2-epimerase 著者 Structural GenomiX 登録日 2003-11-03 公開日 2003-11-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural analysis of a set of proteins resulting from a bacterial genomics project Proteins, 60, 2005

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