PDB: 31311 件ウェブページステータス検索Chemie searchBIRD

---

7M5I	Endolysin from Escherichia coli O157:H7 phage FAHEc1 分子名称: Endolysin, PHOSPHATE ION 著者 Love, M.J, Coombes, D, Billington, C, Dobson, R.C.J. 登録日 2021-03-24 公開日 2021-08-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 The Molecular Basis for Escherichia coli O157:H7 Phage FAHEc1 Endolysin Function and Protein Engineering to Increase Thermal Stability. Viruses, 13, 2021
8T94	Influenza PAN endonuclease with 6-(4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl)-3-hydroxy-4-oxo-1,4-dihydropyridine-2-carboxylic acid 分子名称: (6M)-3-hydroxy-4-oxo-6-[(4M)-4-(1H-tetrazol-5-yl)-2-(trifluoromethyl)phenyl]-1,4-dihydropyridine-2-carboxylic acid, MANGANESE (II) ION, Polymerase acidic protein 著者 Kohlbrand, A.J, Cohen, S.M. 登録日 2023-06-23 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural Studies of Inhibitors with Clinically Relevant Influenza Endonuclease Variants. Biochemistry, 63, 2024
7P9T	Crystal structure of CD73 in complex with dCMP in the open form 分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 5'-nucleotidase, CALCIUM ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-07-27 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
7MDS	Crystal structure of AtDHDPS1 in complex with MBDTA-2 分子名称: 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ... 著者 Hall, C.J, Soares da Costa, T.P, Panjikar, S. 登録日 2021-04-06 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.295 Å) 主引用文献 Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants. Elife, 10, 2021
7P46	Crystal Structure of Xanthomonas campestris Tryptophan 2,3-dioxygenase (TDO) 分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, CYANIDE ION, GLYCEROL, ... 著者 Kwon, H, Basran, J, Booth, E.S, Campbell, L.P, Thackray, S.J, Moody, P.C.E, Mowat, C.G, Raven, E.L. 登録日 2021-07-09 公開日 2021-10-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Binding of l-kynurenine to X. campestris tryptophan 2,3-dioxygenase. J.Inorg.Biochem., 225, 2021
7MLR	X-ray crystal structure of human BRD4(D1) in complex with 2-(4-{5-[6-(3,5-dimethylphenoxy)pyridin-2-yl]-4-methyl-1H-1,2,3-triazol-1- yl}piperidin-1-yl)-N,N-dimethylethan-1-amine (DW34) 分子名称: 1,2-ETHANEDIOL, 2-(4-{5-[6-(3,5-dimethylphenoxy)pyridin-2-yl]-4-methyl-1H-1,2,3-triazol-1-yl}piperidin-1-yl)-N,N-dimethylethan-1-amine, Bromodomain-containing protein 4, ... 著者 Cui, H, Shi, K, Aihara, H, Pomerantz, W.C.K. 登録日 2021-04-28 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 4-Methyl-1,2,3-Triazoles as N -Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity. J.Med.Chem., 64, 2021
7TSX	Structure of Enterobacter cloacae Cap2 bound to CdnD02 C-terminus, Apo state 分子名称: Cap2, Cyclic AMP-AMP-GMP synthase 著者 Ye, Q, Gu, Y, Ledvina, H.E, Quan, Y, Lau, R.K, Zhou, H, Whiteley, A.T, Corbett, K.D. 登録日 2022-01-31 公開日 2023-01-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 An E1-E2 fusion protein primes antiviral immune signalling in bacteria. Nature, 616, 2023
6LOL	The crystal structure of full length IpaH9.8 分子名称: E3 ubiquitin-protein ligase ipaH9.8 著者 Ye, Y, Huang, H. 登録日 2020-01-06 公開日 2020-12-23 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Substrate-binding destabilizes the hydrophobic cluster to relieve the autoinhibition of bacterial ubiquitin ligase IpaH9.8. Commun Biol, 3, 2020
8QA8	Crystal structure of the C-terminally truncated transcriptional repressor protein KorB from the RK2 plasmid complexed with CTP-gamma-S 分子名称: CHLORIDE ION, CYTIDINE-5'-TRIPHOSPHATE, Transcriptional repressor protein KorB 著者 McLean, T.C, Mundy, J.E.A, Lawson, D.M, Le, T.B.K. 登録日 2023-08-22 公開日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the C-terminally truncated transcriptional repressor protein KorB from the RK2 plasmid complexed with CTP-gamma-S To Be Published
7TND	The crystal structure of CYP199A4 bound to 4-phenoxybenzoic acid 分子名称: 4-phenoxybenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-20 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.825 Å) 主引用文献 Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
5FJC	SAM-I riboswitch bearing the H. marismortui Kt-7 variant C-2bU 分子名称: BARIUM ION, MAGNESIUM ION, POTASSIUM ION, ... 著者 Huang, L, Lilley, D.M.J. 登録日 2015-10-07 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
7M1C	Crystal structure of the HCMV pentamer-specific antibody 1-32 分子名称: 1-32 Fab Heavy Chain, 1-32 Fab Light Chain 著者 Wrapp, D, McLellan, J.S. 登録日 2021-03-12 公開日 2021-08-11 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies. Sci Adv, 8, 2022
5FJL	Crystal structure of raptor adenovirus 1 fibre head, wild-type form 分子名称: CHLORIDE ION, FIBER PROTEIN 著者 Nguyen, T.H, van Raaij, M.J. 登録日 2015-10-09 公開日 2016-06-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Crystal Structure of Raptor Adenovirus 1 Fibre Head and Role of the Beta-Hairpin in Siadenovirus Fibre Head Domains Virol.J., 13, 2016
7MFK	Structure of the Clostridium perfringens GH89 in complex with alpha-HNJNAc 分子名称: 1,2-ETHANEDIOL, Alpha-N-acetylglucosaminidase family protein, CALCIUM ION, ... 著者 Boraston, A.B. 登録日 2021-04-09 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Iminosugar C-Glycosides Work as Pharmacological Chaperones of NAGLU, a Glycosidase Involved in MPS IIIB Rare Disease*. Chemistry, 27, 2021
7P53	Crystal Structure of Human gamma-D-crystallin mutant C110M at 1.57 Angstroms resolution 分子名称: Gamma-crystallin D 著者 Strofaldi, A, Khan, A.R, McManus, J. 登録日 2021-07-14 公開日 2021-10-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Surface Exposed Free Cysteine Suppresses Crystallization of Human gamma D-Crystallin. J.Mol.Biol., 433, 2021
7MLQ	X-ray crystal structure of human BRD4(D1) in complex with 2-(4-{5-[6-(2,5-dibromophenoxy)pyridin-2-yl]-4-methyl-1H-1,2,3-triazol-1-yl}piperidin-1-yl)-N,N-dimethylethan-1-amine (compound 26) 分子名称: 1,2-ETHANEDIOL, 2-(4-{5-[6-(2,5-dibromophenoxy)pyridin-2-yl]-4-methyl-1H-1,2,3-triazol-1-yl}piperidin-1-yl)-N,N-dimethylethan-1-amine, Bromodomain-containing protein 4, ... 著者 Cui, H, Johnson, J.A, Vail, N.R, Shi, K, Aihara, H, Pomerantz, W.C.K. 登録日 2021-04-28 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 4-Methyl-1,2,3-Triazoles as N -Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity. J.Med.Chem., 64, 2021
7PA4	Crystal structure of CD73 in complex with CMP in the open form 分子名称: 5'-nucleotidase, CALCIUM ION, CHLORIDE ION, ... 著者 Scaletti, E.R, Strater, N. 登録日 2021-07-28 公開日 2021-10-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signal, 17, 2021
7TNF	The crystal structure of F298V CYP199A4 bound to 4-phenylbenzoic acid 分子名称: CHLORIDE ION, Cytochrome P450, MAGNESIUM ION, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-21 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.539 Å) 主引用文献 Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
5BZ3	CRYSTAL STRUCTURE OF SODIUM PROTON ANTIPORTER NAPA IN OUTWARD-FACING CONFORMATION. 分子名称: (2R)-2,3-DIHYDROXYPROPYL (7Z)-TETRADEC-7-ENOATE, Na(+)/H(+) antiporter 著者 Coincon, M, Uzdavinys, P, Emmanuel, N, Cameron, A, Drew, D. 登録日 2015-06-11 公開日 2016-01-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures reveal the molecular basis of ion translocation in sodium/proton antiporters. Nat.Struct.Mol.Biol., 23, 2016
7TNU	The crystal structure of F298V CYP199A4 bound to 4-cyclohexylbenzoic acid 分子名称: 4-cyclohexylbenzoic acid, CHLORIDE ION, Cytochrome P450, ... 著者 Podgorski, M, Bell, S.G. 登録日 2022-01-21 公開日 2023-01-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.584 Å) 主引用文献 Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry, 28, 2022
5TJE	Murine class I major histocompatibility complex H-2Db in complex with LCMV-derived gp33 and T cell receptor P14 分子名称: ALPHA CHAIN OF MURINE T CELL RECEPTOR p14, BETA CHAIN OF MURINE T CELL RECEPTOR p14, Beta-2-microglobulin, ... 著者 Achour, A, Sandalova, T, Allerbring, E, Popov, A. 登録日 2016-10-04 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Thernary complexes of TCR P14 give insights into the mechanisms behind reestablishment of CTL responses against a viral escape mutant to be published
5FK6	SAM-I riboswitch bearing the H. marismortui Kt-7 variant 3bn is CA 分子名称: BARIUM ION, POTASSIUM ION, S-ADENOSYLMETHIONINE, ... 著者 Huang, L, Lilley, D.M.J. 登録日 2015-10-14 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Critical Base Pair in K-Turns Determines the Conformational Class Adopted, and Correlates with Biological Function. Nucleic Acids Res., 44, 2016
8Q9U	S-methylthiourocanate hydratase, variant R450A, from Variovorax sp. RA8 in complex with NAD+ 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, urocanate hydratase 著者 Vasseur, C.M, Seebeck, F.P. 登録日 2023-08-21 公開日 2024-03-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and Substrate Specificity of S -Methyl Thiourocanate Hydratase. Acs Chem.Biol., 19, 2024
5BZY	X-ray crystal structure of a continuously hydrogen bonded 14mer DNA lattice. 分子名称: DNA (5'-D(*GP*GP*AP*AP*AP*TP*AP*TP*TP*GP*GP*AP*GP*A)-3'), MAGNESIUM ION 著者 Saoji, M, Paukstelis, P.J. 登録日 2015-06-11 公開日 2015-11-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Sequence-dependent structural changes in a self-assembling DNA oligonucleotide. Acta Crystallogr.,Sect.D, 71, 2015
5FLP	Native state mass spectrometry, surface plasmon resonance and X-ray crystallography correlate strongly as a fragment screening combination 分子名称: 5-[(2-chloranylphenoxy)methyl]-1H-1,2,3,4-tetrazole, CARBONIC ANHYDRASE 2, DIMETHYL SULFOXIDE, ... 著者 Woods, L.A, Dolezal, O, Ren, B, Ryan, J.H, Peat, T.S, Poulsen, S.A. 登録日 2015-10-28 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Native State Mass Spectrometry, Surface Plasmon Resonance and X-Ray Crystallography Correlate Strongly as a Fragment Screening Combination. J.Med.Chem., 59, 2016

<512513514515516517518519520521522523524525526527>