7MFK
Structure of the Clostridium perfringens GH89 in complex with alpha-HNJNAc
Summary for 7MFK
Entry DOI | 10.2210/pdb7mfk/pdb |
Descriptor | Alpha-N-acetylglucosaminidase family protein, 1,2-ETHANEDIOL, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | naglu, clostridium perfringens, mps iiib, inhibitor, gh89, glycoside hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) |
Total number of polymer chains | 1 |
Total formula weight | 104007.87 |
Authors | Boraston, A.B. (deposition date: 2021-04-09, release date: 2021-07-28, Last modification date: 2023-10-18) |
Primary citation | Zhu, S.,Jagadeesh, Y.,Tran, A.T.,Imaeda, S.,Boraston, A.,Alonzi, D.S.,Poveda, A.,Zhang, Y.,Desire, J.,Charollais-Thoenig, J.,Demotz, S.,Kato, A.,Butters, T.D.,Jimenez-Barbero, J.,Sollogoub, M.,Bleriot, Y. Iminosugar C-Glycosides Work as Pharmacological Chaperones of NAGLU, a Glycosidase Involved in MPS IIIB Rare Disease*. Chemistry, 27:11291-11297, 2021 Cited by PubMed: 34106504DOI: 10.1002/chem.202101408 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.13 Å) |
Structure validation
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