4Z0J
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![BU of 4z0j by Molmil](/molmil-images/mine/4z0j) | F96S/S73A Double mutant of Plasmodium Falciparum Triosephosphate Isomerase | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, Triosephosphate isomerase | 著者 | Pareek, V, Balaram, P, Murthy, M.R.N. | 登録日 | 2015-03-26 | 公開日 | 2016-02-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Connecting Active-Site Loop Conformations and Catalysis in Triosephosphate Isomerase: Insights from a Rare Variation at Residue 96 in the Plasmodial Enzyme Chembiochem, 17, 2016
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4ZA4
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![BU of 4za4 by Molmil](/molmil-images/mine/4za4) | Structure of A. niger Fdc1 with the prenylated-flavin cofactor in the iminium form. | 分子名称: | 1-deoxy-5-O-phosphono-1-(3,3,4,5-tetramethyl-9,11-dioxo-2,3,8,9,10,11-hexahydro-7H-quinolino[1,8-fg]pteridin-12-ium-7-y l)-D-ribitol, Fdc1, MANGANESE (II) ION, ... | 著者 | Payne, K.A.P, Leys, D. | 登録日 | 2015-04-13 | 公開日 | 2015-06-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.22 Å) | 主引用文献 | New cofactor supports alpha , beta-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition. Nature, 522, 2015
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4Z0S
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4ZLF
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![BU of 4zlf by Molmil](/molmil-images/mine/4zlf) | Cellobionic acid phosphorylase - cellobionic acid complex | 分子名称: | 4-O-beta-D-glucopyranosyl-D-gluconic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Nam, Y.W, Arakawa, T, Fushinobu, S. | 登録日 | 2015-05-01 | 公開日 | 2015-06-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure and Substrate Recognition of Cellobionic Acid Phosphorylase, Which Plays a Key Role in Oxidative Cellulose Degradation by Microbes. J.Biol.Chem., 290, 2015
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4OP5
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![BU of 4op5 by Molmil](/molmil-images/mine/4op5) | Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S mutation | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, Extended spectrum beta-lactamase TEM-63, ... | 著者 | Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. | 登録日 | 2014-02-05 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
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4OP2
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![BU of 4op2 by Molmil](/molmil-images/mine/4op2) | GKRP bound to AMG-0471 and Sorbitol-6-Phosphate | 分子名称: | (2S)-2-{4'-[(6-aminopyridin-3-yl)sulfonyl]biphenyl-4-yl}-1,1,1-trifluoropropan-2-ol, D-SORBITOL-6-PHOSPHATE, GLYCEROL, ... | 著者 | Jordan, S.R, Chmait, S. | 登録日 | 2014-02-04 | 公開日 | 2014-07-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Small Molecule Disruptors of the Glucokinase-Glucokinase Regulatory Protein Interaction: 5. A Novel Aryl Sulfone Series, Optimization Through Conformational Analysis. J.Med.Chem., 58, 2015
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4OPJ
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![BU of 4opj by Molmil](/molmil-images/mine/4opj) | Bh-RNaseH:tcdA-DNA complex | 分子名称: | 5'-D(*CP*GP*CP*GP*AP*(TCY)P*TP*TP*CP*GP*CP*G)-3', GLYCEROL, Ribonuclease H | 著者 | Pallan, P.S, Egli, M. | 登録日 | 2014-02-05 | 公開日 | 2015-02-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.541 Å) | 主引用文献 | Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes. Methods Mol.Biol., 1320
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4Z2K
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![BU of 4z2k by Molmil](/molmil-images/mine/4z2k) | Serratia marcescens Chitinase B complexed with macrolide inhibitor 32 | 分子名称: | (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {7-[N'-(methylcarbamoyl)carbamimidamido]heptyl}carbamate, Chitinase B, GLYCEROL | 著者 | Maita, N, Sugawara, A, Sunazuka, T. | 登録日 | 2015-03-30 | 公開日 | 2015-07-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase J.Med.Chem., 58, 2015
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4Z2P
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4OQH
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![BU of 4oqh by Molmil](/molmil-images/mine/4oqh) | Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S mutation in complex with boron-based inhibitor EC25 | 分子名称: | 1,2-ETHANEDIOL, 3-[(2R)-2-{[(2R)-2-amino-2-phenylacetyl]amino}-2-(dihydroxyboranyl)ethyl]benzoic acid, CALCIUM ION, ... | 著者 | Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. | 登録日 | 2014-02-09 | 公開日 | 2015-05-20 | 最終更新日 | 2018-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
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4OQR
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![BU of 4oqr by Molmil](/molmil-images/mine/4oqr) | Structure of a CYP105AS1 mutant in complex with compactin | 分子名称: | CYP105AS1, Mevastatin, Compactin, ... | 著者 | Leys, D. | 登録日 | 2014-02-10 | 公開日 | 2015-02-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proc.Natl.Acad.Sci.USA, 112, 2015
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4OSX
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4OT7
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![BU of 4ot7 by Molmil](/molmil-images/mine/4ot7) | |
4OTQ
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![BU of 4otq by Molmil](/molmil-images/mine/4otq) | Crystal structure of BTK kinase domain complexed with 1-[5-[3-(7-tert-butyl-4-oxo-quinazolin-3-yl)-2-methyl-phenyl]-1-methyl-2-oxo-3-pyridyl]-3-methyl-urea | 分子名称: | 1-{5-[3-(7-tert-butyl-4-oxoquinazolin-3(4H)-yl)-2-methylphenyl]-1-methyl-2-oxo-1,2-dihydropyridin-3-yl}-3-methylurea, DIMETHYL SULFOXIDE, Tyrosine-protein kinase BTK | 著者 | Kuglstatter, A, Wong, A. | 登録日 | 2014-02-14 | 公開日 | 2014-05-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure-Based Drug Design of RN486, a Potent and Selective Bruton's Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis. J.Med.Chem., 58, 2015
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4Z6K
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4Z74
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4Z7X
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![BU of 4z7x by Molmil](/molmil-images/mine/4z7x) | MdbA protein, a thiol-disulfide oxidoreductase from Actinomyces oris. | 分子名称: | (2S)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, MdbA | 著者 | OSIPIUK, J, Reardon-Robinson, M.E, Ton-That, H, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2015-04-08 | 公開日 | 2015-04-22 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | A Disulfide Bond-forming Machine Is Linked to the Sortase-mediated Pilus Assembly Pathway in the Gram-positive Bacterium Actinomyces oris. J.Biol.Chem., 290, 2015
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4OT1
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4Z1N
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![BU of 4z1n by Molmil](/molmil-images/mine/4z1n) | Carbonic anhydrase inhibitors: Design and synthesis of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms (hCA VII, hCA IX, and hCA XIV) | 分子名称: | 4-[(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)carbonyl]benzenesulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Brynda, J, Pospisilova, K, Rezacova, P, Pachl, P. | 登録日 | 2015-03-27 | 公開日 | 2015-08-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. Eur.J.Med.Chem., 102, 2015
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4OVJ
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4Z1U
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4PUS
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![BU of 4pus by Molmil](/molmil-images/mine/4pus) | Crystal Structure of Influenza A Virus Matrix Protein M1 | 分子名称: | Matrix protein 1 | 著者 | Safo, M.K, Musayev, F.N, Mosier, P.D, Xie, H, Desai, U.R. | 登録日 | 2014-03-13 | 公開日 | 2014-10-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of influenza a virus matrix protein m1: variations on a theme. Plos One, 9, 2014
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4Z23
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![BU of 4z23 by Molmil](/molmil-images/mine/4z23) | BspA_C_WT | 分子名称: | 1,2-ETHANEDIOL, Cell wall surface anchor protein | 著者 | Race, P, Rego, S. | 登録日 | 2015-03-28 | 公開日 | 2016-06-29 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | BspA_C_WT To Be Published
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4OW1
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![BU of 4ow1 by Molmil](/molmil-images/mine/4ow1) | Crystal Structure of Resuscitation Promoting Factor C | 分子名称: | 1,2-ETHANEDIOL, Resuscitation-promoting factor RpfC | 著者 | Chauviac, F.X, Quay, D.H.X, Cohen-Gonsaud, M, Keep, N.H. | 登録日 | 2014-01-29 | 公開日 | 2014-06-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The RpfC (Rv1884) atomic structure shows high structural conservation within the resuscitation-promoting factor catalytic domain. Acta Crystallogr.,Sect.F, 70, 2014
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4Z29
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