4OSX

STRUCTURE of UNCLEAVED GLYCINE-BOUND HUMAN L-ASPARAGINASE PROTEIN

Replaces:  4HLO

Summary for 4OSX

• Entry DOI: 10.2210/pdb4osx/pdb
• Related: 4OSY
• Descriptor: Isoaspartyl peptidase/L-asparaginase, SODIUM ION, GLYCINE, ... (4 entities in total)
• Functional Keywords: ntn enzyme, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q7L266
• Total number of polymer chains: 2
• Total formula weight: 64886.59

Authors

Nomme, J.,Lavie, A. (deposition date: 2014-02-13, release date: 2014-03-05, Last modification date: 2023-09-20)

• Primary citation: Su, Y.,Karamitros, C.S.,Nomme, J.,Mcsorley, T.,Konrad, M.,Lavie, A.; Free Glycine Accelerates the Autoproteolytic Activation of Human Asparaginase.; Chem.Biol., 20:533-, 2013; PubMed: 23601642; DOI: 10.1016/J.CHEMBIOL.2013.03.006

Experimental method

X-RAY DIFFRACTION (1.95 Å)