4OT1

Structural Basis for the Recognition of Human Cytomegalovirus Glycoprotein B by the Neutralizing Human Antibody SM5-1

Summary for 4OT1

• Entry DOI: 10.2210/pdb4ot1/pdb
• Related: 4OSN 4OSU
• Descriptor: Envelope glycoprotein B, SM5-1 Fab Heavy Chain, SM5-1 Fab Light Chain, ... (6 entities in total)
• Functional Keywords: immunoglobulin, ph domain, antibody-antigen recognition, viral protein-immune system complex, viral protein/immune system
• Biological source: Human Cytomegalovirus (HHV-5); More
• Cellular location: Virion membrane ; Single-pass type I membrane protein : P13201
• Total number of polymer chains: 3
• Total formula weight: 62298.68

Authors

Diestel, U.,Muller, Y.A. (deposition date: 2014-02-13, release date: 2014-08-13, Last modification date: 2017-08-23)

• Primary citation: Spindler, N.,Diestel, U.,Stump, J.D.,Wiegers, A.K.,Winkler, T.H.,Sticht, H.,Mach, M.,Muller, Y.A.; Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody.; Plos Pathog., 10:e1004377-e1004377, 2014; PubMed: 25299639; DOI: 10.1371/journal.ppat.1004377

Experimental method

X-RAY DIFFRACTION (2.11 Å)