4OSU

Crystal structure of HCMV gB-neutralizing SM5-1 Fab fragment

Summary for 4OSU

• Entry DOI: 10.2210/pdb4osu/pdb
• Related: 4OSN 4OT1
• Descriptor: SM5-1 Fab Heavy Chain, SM5-1 Fab Light Chain, FORMIC ACID, ... (5 entities in total)
• Functional Keywords: immunoglobulin, immune response, hcmv neutralization, hcmv glycoprotein b, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 2
• Total formula weight: 47829.29

Authors

Diestel, U.,Muller, Y.A. (deposition date: 2014-02-13, release date: 2014-08-13, Last modification date: 2014-10-22)

• Primary citation: Spindler, N.,Diestel, U.,Stump, J.D.,Wiegers, A.K.,Winkler, T.H.,Sticht, H.,Mach, M.,Muller, Y.A.; Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody.; Plos Pathog., 10:e1004377-e1004377, 2014; PubMed: 25299639; DOI: 10.1371/journal.ppat.1004377

Experimental method

X-RAY DIFFRACTION (1.87 Å)